BrainRegionLPC SC PH UMG

Upper Marginal Nucleus

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This page covers biological details of component Upper Marginal Nucleus. Region is part of aHuman target integrated biological model.

• Top-down path to region: Spinal Cord -> Posterior/Dorsal Horn (BMA.SC.PH) -> Lamina I (LPC.SC.PH.L1) -> Marginal Nucleus (LPC.SC.PH.MG) -> Upper Marginal Nucleus (LPC.SC.PH.UMG) (see Mind Maps)
• Type: nucleus
• Quality: L0
• Brain area: Lower Brain - Peripheral Control Area
• Role: sensory.nucleus
• Function: Relay information related to pain and temperature sensation - C1-C8,T1-T6

(generated)

Components

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• no child items defined

Connectivity

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Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
LMC	LMC.HL.RP.PL	Raphe Pallidus Nucleus	modulatory-5ht	(unknown reference)
LPC	LPC.PN.SG.UDRG	Upper Dorsal Root Ganglion	excitatory-glu	(unknown reference)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
NCP	NCP.FD.TH.LI	Limitans Nucleus of Thalamus	excitatory-glu	Afferent pain pathways (SC -> Thalamus, abstract)
	NCP.FD.TH.VPI	Ventral Posteroinferior Nucleus	excitatory-glu	Afferent pain pathways (SC -> Thalamus, abstract)
	NCP.FD.TH.VPL	Ventral Posterolateral Nucleus	excitatory-glu	Afferent pain pathways (SC -> Thalamus, abstract)
NDM	NDM.FD.TH.SM	Submedial Nucleus of Thalamus	excitatory-glu	Afferent pain pathways (SC -> Thalamus, abstract)

Thirdparty Circuits

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• Afferent pain pathways - see Reference (CF.PAIN-PATH)

ACC=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area)
AMY=Amygdala,FAM.FT.AM
BG=Basal Ganglia,FEC.FT.BG
Cerebellum=Cerebellar Complex,LLC.HT.CRC
Insula=Insular Cortex,NC.INS
PAG=Periaqueductal Gray Matter,LMC.MM.PAG
PB=Parabrachial Nucleus,LPC.HT.PRF.PB
PFC=Prefrontal Cortex,NC.AL.PFC
S1=Primary Somatosensory Cortex,NCP.NC.PG.S1
S2=Secondary Somatosensory Cortex,NCP.NC.PG.S2
SC=Posterior/Dorsal Horn,BMA.SC.PH
Thalamus=Sensory Thalamus,FD.TH.SR

References

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• http://www.nature.com/nrn/journal/v14/n7/fig_tab/nrn3516_F2.html