Revision as of 19:04, 28 November 2018

Wernicke's area A4

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This page covers biological details of component Wernicke's area A4. Region is part of aHuman target integrated biological model.

Top-down path to region: Cerebral Cortex -> Temporal Lobe (NC.LOBE.TEMP) -> Superior Temporal Gyrus (NC.STG) -> Wernicke's area A4 (NSA.NC.STG.A4) (see Mind Maps)
Type: cortex
Brain area: Neocortical Brain - Sensory Aggregation Area
Brodmann ID: 22
Role: cortex.generic
Function: Coordinate the activation or deactivation of grammar areas
Notes to function: 22b, Grammatical areas, phonemic sequences, word comprehension

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Components

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no child items defined

Connectivity

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NSA.NC.STG.A4.dot.png

Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
NSA	NSA.NC.OCC.MT	Middle Temporal Area	feedforward-glu	Category-Selectivity Paradigm (IOG -> STS, abstract)
	NSA.NC.TTG.A1	Primary Auditory Cortex	feedforward-glu	Vocal Control (A1 -> Wernike)
	NSA.NC.TTG.A2	Auditory Association Area	feedforward-glu	Cortical Auditory System (Belt42 -> AC22)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
FMM	FMM.NC.PH.LEC	Lateral Entorhinal Cortex	feedforward-glu	(unknown reference)
NMA	NMA.NC.PMC.F4	Ventral Caudal Premotor Cortex	feedforward-glu	Language-Related Regions (pSTC -> PMC, abstract)
NPE	NPE.NC.BRA.PT	Broca's Area Pars Triangularis	feedforward-glu	Language-Related Regions (pSTC -> BA44, abstract)
	NPE.NC.IPL.SMW	Supramarginal Wernike Cortex	feedforward-glu	Cortical Auditory System (AC22 -> IPL40, abstract)
NSA	NSA.NC.STG.A3	Wernicke's area A3	feedforward-glu	Cortical Auditory System (AC22 -> STS22)

Thirdparty Circuits

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Language-Related Regions - see Reference

map: 
BA44=Broca's Area,NPE.NC.PFC.BRA (see Lateral Prefrontal Cortex)
BA45=Broca's Area,NPE.NC.PFC.BRA (see Lateral Prefrontal Cortex)
IFG=Broca's Area,NPE.NC.PFC.BRA (see Lateral Prefrontal Cortex)
MTG21=Preoccipital Inferotemporal Area,NSA.NC.IT.TEO
PMC=Premotor Cortex,NC.PMC
STG22a=Wernicke's area A3,NSA.NC.STG.A3
STG22b=Wernicke's area A4,NSA.NC.STG.A4
TC=Temporopolar Cortex,NCP.NC.TPC
pSTC=Wernicke's area A4,NSA.NC.STG.A4
vIFC=Inferior Prefrontal Gyrus,NDM.NC.AL.IPG

Directed Effort Network - see Reference

map: 
AC22=Wernicke's area A4,NSA.NC.STG.A4
ACA=Auditory Association Area,NSA.NC.TTG.A2
AM=Amygdala,FAM.FT.AM
DLPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex)
HC=Hippocampus,FMM.FT.HC (see Hippocampal Formation)
Insula=Insular Cortex,NC.INS
OPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)
PPC=Inferior Parietal Lobule,NC.IPL
dACC=Dorsal Anterior Cingulate Area,NDM.NC.AL.DACG
fPole=Inferior Prefrontal Gyrus,NDM.NC.AL.IPG
tPole=Temporopolar Cortex,NCP.NC.TPC
vACC=Ventral Anterior Cingulate Area,NDM.NC.AL.VACG

Cortical Auditory System - see Reference

map: 
AC22=Wernicke's area A4,NSA.NC.STG.A4
Belt42=Auditory Association Area,NSA.NC.TTG.A2
Core41=Primary Auditory Cortex,NSA.NC.TTG.A1
IFC44=Broca's Area,NPE.NC.PFC.BRA (see Lateral Prefrontal Cortex)
IFC45=Broca's Area,NPE.NC.PFC.BRA (see Lateral Prefrontal Cortex)
IPL40=Supramarginal Gyrus,NC.IPL.SMG (see Inferior Parietal Lobule)
PMC6=Ventral Premotor Cortex,MCA.NC.VPMC (see Premotor Cortex)
PMC8=Anterior Frontal Eye Field,NPE.NC.PMC.AFEF
STS22=Wernicke's area A3,NSA.NC.STG.A3

Vocal Control - see Reference

map: 
A1=Primary Auditory Cortex,NSA.NC.TTG.A1
Broca=Broca's Area,NPE.NC.PFC.BRA (see Lateral Prefrontal Cortex)
M2=Supplementary Motor Cortex,NMA.NC.SMC
MotorV=Trigeminal Motor Nucleus,LPC.HT.TRM
MotorVII=Facial Motor Nucleus,LPC.HT.FCM
NucleusAmbiguus=Ambiguus Nucleus,LPC.HL.AMB
NucleusXII=Hypoglossal Motor Nucleus,LPC.HL.HYG
Premotor24=Ventral Anterior Cingulate Area,NDM.NC.AL.VACG
RF=Pontine Reticular Formation,HT.RF
Wernike=Wernicke's area A4,NSA.NC.STG.A4

References

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@@ Line 1: / Line 1: @@
 <pre style="color: green">Wernicke's area A4</pre>
 @@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainAreaNSA]] -> [[BrainRegionNSA_NC_STG_A4]]
@@ Line 60: / Line 59: @@
 * [http://ars.els-cdn.com/content/image/1-s2.0-S1364661312002823-gr2.jpg Language-Related Regions] - see [http://www.sciencedirect.com/science/article/pii/S1364661312002823 Reference]
-map: BA44=Broca's Area,NPE.NC.PFC.BRA ([[BrainRegionNPE_NC_BRA_PO|Broca's Area Pars Opercularis]] (NPE.NC.BRA.PO), [[BrainRegionNPE_NC_BRA_PT|Broca's Area Pars Triangularis]] (NPE.NC.BRA.PT)), BA45=Broca's Area,NPE.NC.PFC.BRA ([[BrainRegionNPE_NC_BRA_PO|Broca's Area Pars Opercularis]] (NPE.NC.BRA.PO), [[BrainRegionNPE_NC_BRA_PT|Broca's Area Pars Triangularis]] (NPE.NC.BRA.PT)), IFG=Broca's Area,NPE.NC.PFC.BRA ([[BrainRegionNPE_NC_BRA_PO|Broca's Area Pars Opercularis]] (NPE.NC.BRA.PO), [[BrainRegionNPE_NC_BRA_PT|Broca's Area Pars Triangularis]] (NPE.NC.BRA.PT)), MTG21=[[BrainRegionNSA_NC_IT_TEO|Preoccipital Inferotemporal Area,NSA.NC.IT.TEO]], PMC=[[BrainCenter|Premotor Cortex,NC.PMC]], STG22a=[[BrainRegionNSA_NC_STG_A3|Wernicke's area A3,NSA.NC.STG.A3]], STG22b=[[BrainRegionNSA_NC_STG_A4|Wernicke's area A4,NSA.NC.STG.A4]], TC=[[BrainRegionNCP_NC_TPC|Temporopolar Cortex,NCP.NC.TPC]], pSTC=[[BrainRegionNSA_NC_STG_A4|Wernicke's area A4,NSA.NC.STG.A4]], vIFC=[[BrainRegionNDM_NC_AL_IPG|Inferior Prefrontal Gyrus,NDM.NC.AL.IPG]]
+ map:
-<img src="http://ahuman.org/svn/ahwiki/images/ext/e470d01e8c2325c44b4856d7480d408c.jpg" alt="unavailable" style="max-width: 100%;">
+ BA44=Broca's Area,NPE.NC.PFC.BRA (see [[BrainCenterNC_AL_LPFC|Lateral Prefrontal Cortex]])
+ BA45=Broca's Area,NPE.NC.PFC.BRA (see [[BrainCenterNC_AL_LPFC|Lateral Prefrontal Cortex]])
+ IFG=Broca's Area,NPE.NC.PFC.BRA (see [[BrainCenterNC_AL_LPFC|Lateral Prefrontal Cortex]])
+ MTG21=[[BrainRegionNSA_NC_IT_TEO|Preoccipital Inferotemporal Area,NSA.NC.IT.TEO]]
+ PMC=[[BrainCenterNC_PMC|Premotor Cortex,NC.PMC]]
+ STG22a=[[BrainRegionNSA_NC_STG_A3|Wernicke's area A3,NSA.NC.STG.A3]]
+ STG22b=[[BrainRegionNSA_NC_STG_A4|Wernicke's area A4,NSA.NC.STG.A4]]
+ TC=[[BrainRegionNCP_NC_TPC|Temporopolar Cortex,NCP.NC.TPC]]
+ pSTC=[[BrainRegionNSA_NC_STG_A4|Wernicke's area A4,NSA.NC.STG.A4]]
+ vIFC=[[BrainRegionNDM_NC_AL_IPG|Inferior Prefrontal Gyrus,NDM.NC.AL.IPG]]
+<img src="http://ahuman.org/svn/ahwiki/images/ext/e470d01e8c2325c44b4856d7480d408c.jpg" alt=alt="unavailable" style="max-width: 100%;">
 * [http://c431376.r76.cf2.rackcdn.com/18691/fnhum-06-00184-HTML/image_m/fnhum-06-00184-g001.jpg Directed Effort Network] - see [http://www.frontiersin.org/Human_Neuroscience/10.3389/fnhum.2012.00184/full Reference]
-map: AC22=[[BrainRegionNSA_NC_STG_A4|Wernicke's area A4,NSA.NC.STG.A4]], ACA=[[BrainRegionNSA_NC_TTG_A2|Auditory Association Area,NSA.NC.TTG.A2]], AM=[[BrainCenter|Amygdala,FAM.FT.AM]], DLPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC ([[BrainRegionNDM_NC_AL_DLPFCR|Rostral Mid-Dorsolateral Prefrontal Cortex]] (NDM.NC.AL.DLPFCR), [[BrainRegionNDM_NC_AL_DLPFCL|Lateral Mid-Dorsolateral Prefrontal Cortex]] (NDM.NC.AL.DLPFCL)), HC=Hippocampus,FMM.FT.HC ([[BrainRegionFMM_FT_HC_DG|Dentate Gyrus]] (FMM.FT.HC.DG), [[BrainRegionFMM_FT_HC_CA1P|Proximal CA1 of Hippocampus]] (FMM.FT.HC.CA1P), [[BrainRegionFMM_FT_HC_CA1M|Middle CA1 of Hippocampus]] (FMM.FT.HC.CA1M), [[BrainRegionFMM_FT_HC_CA1D|Distal CA1 of Hippocampus]] (FMM.FT.HC.CA1D), [[BrainRegionFMM_FT_HC_CA2|Dorsolateral Cornu Ammonis of Hippocampus]] (FMM.FT.HC.CA2), [[BrainRegionFMM_FT_HC_CA3P|Proximal CA3 of Hippocampus]] (FMM.FT.HC.CA3P), [[BrainRegionFMM_FT_HC_CA3M|Middle CA3 of Hippocampus]] (FMM.FT.HC.CA3M), [[BrainRegionFMM_FT_HC_CA3D|Distal CA3 of Hippocampus]] (FMM.FT.HC.CA3D)), Insula=[[BrainCenter|Insular Cortex,NC.INS]], OPFC=Orbitofrontal Cortex,NC.AL.OPFC ([[BrainRegionNDM_NC_AL_FPC|Lateral Frontopolar Cortex]] (NDM.NC.AL.FPC), [[BrainRegionNDM_NC_AL_ROFCR|Most Rostral Orbitofrontal Cortex]] (NDM.NC.AL.ROFCR), [[BrainRegionNDM_NC_AL_ROFCS|Sulcal Rostral Orbitofrontal Cortex]] (NDM.NC.AL.ROFCS), [[BrainRegionNDM_NC_AL_ROFCM|Medial Rostral Orbitofrontal Cortex]] (NDM.NC.AL.ROFCM), [[BrainRegionNDM_NC_AL_ROFCL|Lateral Rostral Orbitofrontal Cortex]] (NDM.NC.AL.ROFCL)), PPC=[[BrainCenter|Inferior Parietal Lobule,NC.IPL]], dACC=[[BrainRegionNDM_NC_AL_DACG|Dorsal Anterior Cingulate Area,NDM.NC.AL.DACG]], fPole=[[BrainRegionNDM_NC_AL_IPG|Inferior Prefrontal Gyrus,NDM.NC.AL.IPG]], tPole=[[BrainRegionNCP_NC_TPC|Temporopolar Cortex,NCP.NC.TPC]], vACC=[[BrainRegionNDM_NC_AL_VACG|Ventral Anterior Cingulate Area,NDM.NC.AL.VACG]]
+ map:
-<img src="http://ahuman.org/svn/ahwiki/images/ext/4770740a2066720a5b5aa9ee4cb2f3bc.jpg" alt="unavailable" style="max-width: 100%;">
+ AC22=[[BrainRegionNSA_NC_STG_A4|Wernicke's area A4,NSA.NC.STG.A4]]
+ ACA=[[BrainRegionNSA_NC_TTG_A2|Auditory Association Area,NSA.NC.TTG.A2]]
+ AM=[[BrainCenterFAM_FT_AM|Amygdala,FAM.FT.AM]]
+ DLPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see [[BrainCenterNC_AL_LPFC|Lateral Prefrontal Cortex]])
+ HC=Hippocampus,FMM.FT.HC (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]])
+ Insula=[[BrainCenterNC_INS|Insular Cortex,NC.INS]]
+ OPFC=Orbitofrontal Cortex,NC.AL.OPFC (see [[BrainCenterNC_AL_OMPFC|Orbitomedial Prefrontal Cortex]])
+ PPC=[[BrainCenterNC_IPL|Inferior Parietal Lobule,NC.IPL]]
+ dACC=[[BrainRegionNDM_NC_AL_DACG|Dorsal Anterior Cingulate Area,NDM.NC.AL.DACG]]
+ fPole=[[BrainRegionNDM_NC_AL_IPG|Inferior Prefrontal Gyrus,NDM.NC.AL.IPG]]
+ tPole=[[BrainRegionNCP_NC_TPC|Temporopolar Cortex,NCP.NC.TPC]]
+ vACC=[[BrainRegionNDM_NC_AL_VACG|Ventral Anterior Cingulate Area,NDM.NC.AL.VACG]]
+<img src="http://ahuman.org/svn/ahwiki/images/ext/4770740a2066720a5b5aa9ee4cb2f3bc.jpg" alt=alt="unavailable" style="max-width: 100%;">
 * [http://www.nature.com/neuro/journal/v12/n6/images/nn.2331-F5.jpg Cortical Auditory System] - see [http://www.nature.com/neuro/journal/v12/n6/fig_tab/nn.2331_F5.html Reference]
-map: AC22=[[BrainRegionNSA_NC_STG_A4|Wernicke's area A4,NSA.NC.STG.A4]], Belt42=[[BrainRegionNSA_NC_TTG_A2|Auditory Association Area,NSA.NC.TTG.A2]], Core41=[[BrainRegionNSA_NC_TTG_A1|Primary Auditory Cortex,NSA.NC.TTG.A1]], IFC44=Broca's Area,NPE.NC.PFC.BRA ([[BrainRegionNPE_NC_BRA_PO|Broca's Area Pars Opercularis]] (NPE.NC.BRA.PO), [[BrainRegionNPE_NC_BRA_PT|Broca's Area Pars Triangularis]] (NPE.NC.BRA.PT)), IFC45=Broca's Area,NPE.NC.PFC.BRA ([[BrainRegionNPE_NC_BRA_PO|Broca's Area Pars Opercularis]] (NPE.NC.BRA.PO), [[BrainRegionNPE_NC_BRA_PT|Broca's Area Pars Triangularis]] (NPE.NC.BRA.PT)), IPL40=Supramarginal Gyrus,NC.IPL.SMG ([[BrainRegionNPE_NC_IPL_SMW|Supramarginal Wernike Cortex]] (NPE.NC.IPL.SMW)), PMC6=Ventral Premotor Cortex,MCA.NC.VPMC ([[BrainRegionNMA_NC_PMC_F4|Ventral Caudal Premotor Cortex]] (NMA.NC.PMC.F4), [[BrainRegionNMA_NC_PMC_F5|Ventral Rostral Premotor Cortex]] (NMA.NC.PMC.F5)), PMC8=[[BrainRegionNPE_NC_PMC_AFEF|Anterior Frontal Eye Field,NPE.NC.PMC.AFEF]], STS22=[[BrainRegionNSA_NC_STG_A3|Wernicke's area A3,NSA.NC.STG.A3]]
+ map:
-<img src="http://ahuman.org/svn/ahwiki/images/ext/93dc9c466b42f33ebd6a47d33a42313f.jpg" alt="unavailable" style="max-width: 100%;">
+ AC22=[[BrainRegionNSA_NC_STG_A4|Wernicke's area A4,NSA.NC.STG.A4]]
+ Belt42=[[BrainRegionNSA_NC_TTG_A2|Auditory Association Area,NSA.NC.TTG.A2]]
+ Core41=[[BrainRegionNSA_NC_TTG_A1|Primary Auditory Cortex,NSA.NC.TTG.A1]]
+ IFC44=Broca's Area,NPE.NC.PFC.BRA (see [[BrainCenterNC_AL_LPFC|Lateral Prefrontal Cortex]])
+ IFC45=Broca's Area,NPE.NC.PFC.BRA (see [[BrainCenterNC_AL_LPFC|Lateral Prefrontal Cortex]])
+ IPL40=Supramarginal Gyrus,NC.IPL.SMG (see [[BrainCenterNC_IPL|Inferior Parietal Lobule]])
+ PMC6=Ventral Premotor Cortex,MCA.NC.VPMC (see [[BrainCenterNC_PMC|Premotor Cortex]])
+ PMC8=[[BrainRegionNPE_NC_PMC_AFEF|Anterior Frontal Eye Field,NPE.NC.PMC.AFEF]]
+ STS22=[[BrainRegionNSA_NC_STG_A3|Wernicke's area A3,NSA.NC.STG.A3]]
+<img src="http://ahuman.org/svn/ahwiki/images/ext/93dc9c466b42f33ebd6a47d33a42313f.jpg" alt=alt="unavailable" style="max-width: 100%;">
 * [http://c431376.r76.cf2.rackcdn.com/10053/fnana-05-00034-r1/image_m/fnana-05-00034-g002.jpg Vocal Control] - see [http://www.frontiersin.org/neuroanatomy/10.3389/fnana.2011.00034/full Reference]
-map: A1=[[BrainRegionNSA_NC_TTG_A1|Primary Auditory Cortex,NSA.NC.TTG.A1]], Broca=Broca's Area,NPE.NC.PFC.BRA ([[BrainRegionNPE_NC_BRA_PO|Broca's Area Pars Opercularis]] (NPE.NC.BRA.PO), [[BrainRegionNPE_NC_BRA_PT|Broca's Area Pars Triangularis]] (NPE.NC.BRA.PT)), M2=[[BrainCenter|Supplementary Motor Cortex,NMA.NC.SMC]], MotorV=[[BrainRegionLPC_HT_TRM|Trigeminal Motor Nucleus,LPC.HT.TRM]], MotorVII=[[BrainRegionLPC_HT_FCM|Facial Motor Nucleus,LPC.HT.FCM]], NucleusAmbiguus=[[BrainRegionLPC_HL_AMB|Ambiguus Nucleus,LPC.HL.AMB]], NucleusXII=[[BrainRegionLPC_HL_HYG|Hypoglossal Motor Nucleus,LPC.HL.HYG]], Premotor24=[[BrainRegionNDM_NC_AL_VACG|Ventral Anterior Cingulate Area,NDM.NC.AL.VACG]], RF=[[BrainCenter|Pontine Reticular Formation,HT.RF]], Wernike=[[BrainRegionNSA_NC_STG_A4|Wernicke's area A4,NSA.NC.STG.A4]]
+ map:
-<img src="http://ahuman.org/svn/ahwiki/images/ext/d7ea49d94cfa13f82767b076295ae18c.jpg" alt="unavailable" style="max-width: 100%;">
+ A1=[[BrainRegionNSA_NC_TTG_A1|Primary Auditory Cortex,NSA.NC.TTG.A1]]
+ Broca=Broca's Area,NPE.NC.PFC.BRA (see [[BrainCenterNC_AL_LPFC|Lateral Prefrontal Cortex]])
+ M2=[[BrainCenterNMA_NC_SMC|Supplementary Motor Cortex,NMA.NC.SMC]]
+ MotorV=[[BrainRegionLPC_HT_TRM|Trigeminal Motor Nucleus,LPC.HT.TRM]]
+ MotorVII=[[BrainRegionLPC_HT_FCM|Facial Motor Nucleus,LPC.HT.FCM]]
+ NucleusAmbiguus=[[BrainRegionLPC_HL_AMB|Ambiguus Nucleus,LPC.HL.AMB]]
+ NucleusXII=[[BrainRegionLPC_HL_HYG|Hypoglossal Motor Nucleus,LPC.HL.HYG]]
+ Premotor24=[[BrainRegionNDM_NC_AL_VACG|Ventral Anterior Cingulate Area,NDM.NC.AL.VACG]]
+ RF=[[BrainCenterHT_RF|Pontine Reticular Formation,HT.RF]]
+ Wernike=[[BrainRegionNSA_NC_STG_A4|Wernicke's area A4,NSA.NC.STG.A4]]
+<img src="http://ahuman.org/svn/ahwiki/images/ext/d7ea49d94cfa13f82767b076295ae18c.jpg" alt=alt="unavailable" style="max-width: 100%;">

Difference between revisions of "BrainRegionNSA NC STG A4"

Revision as of 19:04, 28 November 2018

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