Revision as of 18:56, 28 November 2018

Arcuate Nucleus of Hypothalamus

@@Home -> BiologicalLifeResearch -> BrainAreaLAC -> BrainRegionLAC_FD_HT_AR

This page covers biological details of component Arcuate Nucleus of Hypothalamus. Region is part of aHuman target integrated biological model.

Top-down path to region: Forebrain Diencephalon -> Hypothalamus (FD.HT) -> Anterior Hypothalamus Area (LAC.FD.HT.AHT) -> Tuberal Area (LAC.FD.HT.TUB) -> Arcuate Nucleus of Hypothalamus (LAC.FD.HT.AR) (see Mind Maps)
Type: nucleus
Brain area: Lower Brain - Autonomous Control Area
Role: processor.autonomic
Function: Regulation of growth, appetite and body weight
Notes to function: lateral of tuberlulum, TIDA - releases dopamine to regulate secretion of prolactin hormone, GHRH - stimulate growth hormone secretion (ventrolateral)

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Components

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no child items defined

Connectivity

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LAC.FD.HT.AR.dot.png

Inbound Region Connections:

no connections

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
LAC	LAC.FD.HT.DM	Dorsomedial Hypothalamic Nucleus	excitatory-glu	Intrahypothalamic connections important for neural control of food intake and energy balance (ARC -> DMN)
	LAC.FD.HT.LTN	Lateral Hypothalamic Nucleus	excitatory-glu	Intrahypothalamic connections important for neural control of food intake and energy balance (ARC -> LHA)
	LAC.FD.HT.PV	Paraventricular Nucleus	excitatory-glu	Intrahypothalamic connections important for neural control of food intake and energy balance (ARC -> PA)
	LAC.FD.HT.VM	Ventromedial Hypothalamic Nucleus	excitatory-glu	Schematic of hypothalamic circuitry underlying satiety (ARC -> VMH)
TEA	TARGET.TEA.ENDOCRINE	Endocrine Glands	endocrine-adenohypophysis	(unknown reference)

Thirdparty Circuits

(generated)

Intrahypothalamic connections important for neural control of food intake and energy balance - see Reference

map: 
AH=Anterior Hypothalamic Nucleus,LAC.FD.HT.AH
ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR
DMN=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM
LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN
MPOA=Median Preoptic Nucleus,LAC.FD.HT.MPO
PA=Paraventricular Nucleus,LAC.FD.HT.PV
SCH=Suprachiasmatic Nucleus,LAC.FD.HT.SCN
SON=Supraoptic Nucleus,LAC.FD.HT.SO
VMN=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM

Schematic of hypothalamic circuitry underlying satiety - see Reference

map: 
ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR
DMH=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM
LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN
NTS=Solitary Nucleus,LPC.HL.SOL
PVN=Paraventricular Nucleus,LAC.FD.HT.PV
VMH=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM

Glucose-sensing neural network - see Reference

map: 
ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR
DMN=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM
LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN
PVH=Paraventricular Nucleus,LAC.FD.HT.PV
VMH=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM

Eating and sleeping to survive - see Reference

map: 
ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR
DMH=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM
LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN
MPO=Median Preoptic Nucleus,LAC.FD.HT.MPO
PVH=Paraventricular Nucleus,LAC.FD.HT.PV
SCN=Suprachiasmatic Nucleus,LAC.FD.HT.SCN
VLPO=Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO
VMH=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM

Bowels control brain: gut hormones and obesity - see Reference

map: 
AMY=Amygdala,FAM.FT.AM
ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR
DS=Dorsal Striatum,FEC.FT.DST (see Basal Ganglia)
LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN
ME=Endocrine Glands,TARGET.TEA.ENDOCRINE
NAc=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia)
NTS=Solitary Nucleus,LPC.HL.SOL
OFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)
PBN=Parabrachial Nucleus,LPC.HT.PRF.PB
PVN=Paraventricular Nucleus,LAC.FD.HT.PV
VMN=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM
VTA=Ventral Tegmental Area,LMC.MM.VTA

References

(generated)

@@ Line 1: / Line 1: @@
 <pre style="color: green">Arcuate Nucleus of Hypothalamus</pre>
 @@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainAreaLAC]] -> [[BrainRegionLAC_FD_HT_AR]]
@@ Line 50: / Line 49: @@
 * [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/intrahypothalamic.png Intrahypothalamic connections important for neural control of food intake and energy balance] - see [http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf Reference]
-map: AH=[[BrainRegionLAC_FD_HT_AH|Anterior Hypothalamic Nucleus,LAC.FD.HT.AH]], ARC=[[BrainRegionLAC_FD_HT_AR|Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR]], DMN=[[BrainRegionLAC_FD_HT_DM|Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM]], LHA=[[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]], MPOA=[[BrainRegionLAC_FD_HT_MPO|Median Preoptic Nucleus,LAC.FD.HT.MPO]], PA=[[BrainRegionLAC_FD_HT_PV|Paraventricular Nucleus,LAC.FD.HT.PV]], SCH=[[BrainRegionLAC_FD_HT_SCN|Suprachiasmatic Nucleus,LAC.FD.HT.SCN]], SON=[[BrainRegionLAC_FD_HT_SO|Supraoptic Nucleus,LAC.FD.HT.SO]], VMN=[[BrainRegionLAC_FD_HT_VM|Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM]]
+ map:
-<img src="http://ahuman.org/svn/ahwiki/images/ext/812cda92ff47d048aeb22ce670a9a9fb.png" alt="unavailable" style="max-width: 100%;">
+ AH=[[BrainRegionLAC_FD_HT_AH|Anterior Hypothalamic Nucleus,LAC.FD.HT.AH]]
+ ARC=[[BrainRegionLAC_FD_HT_AR|Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR]]
+ DMN=[[BrainRegionLAC_FD_HT_DM|Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM]]
+ LHA=[[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]]
+ MPOA=[[BrainRegionLAC_FD_HT_MPO|Median Preoptic Nucleus,LAC.FD.HT.MPO]]
+ PA=[[BrainRegionLAC_FD_HT_PV|Paraventricular Nucleus,LAC.FD.HT.PV]]
+ SCH=[[BrainRegionLAC_FD_HT_SCN|Suprachiasmatic Nucleus,LAC.FD.HT.SCN]]
+ SON=[[BrainRegionLAC_FD_HT_SO|Supraoptic Nucleus,LAC.FD.HT.SO]]
+ VMN=[[BrainRegionLAC_FD_HT_VM|Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM]]
+<img src="http://ahuman.org/svn/ahwiki/images/ext/812cda92ff47d048aeb22ce670a9a9fb.png" alt=alt="unavailable" style="max-width: 100%;">
 * [http://neuroscience.uth.tmc.edu/s4/images/dougherty/pdougherty4_3.jpg Schematic of hypothalamic circuitry underlying satiety] - see [http://neuroscience.uth.tmc.edu/s4/chapter04.html Reference]
-map: ARC=[[BrainRegionLAC_FD_HT_AR|Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR]], DMH=[[BrainRegionLAC_FD_HT_DM|Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM]], LHA=[[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]], NTS=[[BrainRegionLPC_HL_SOL|Solitary Nucleus,LPC.HL.SOL]], PVN=[[BrainRegionLAC_FD_HT_PV|Paraventricular Nucleus,LAC.FD.HT.PV]], VMH=[[BrainRegionLAC_FD_HT_VM|Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM]]
+ map:
-<img src="http://ahuman.org/svn/ahwiki/images/ext/6f1f0e26e147b046d3567a72e62038bb.jpg" alt="unavailable" style="max-width: 100%;">
+ ARC=[[BrainRegionLAC_FD_HT_AR|Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR]]
+ DMH=[[BrainRegionLAC_FD_HT_DM|Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM]]
+ LHA=[[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]]
+ NTS=[[BrainRegionLPC_HL_SOL|Solitary Nucleus,LPC.HL.SOL]]
+ PVN=[[BrainRegionLAC_FD_HT_PV|Paraventricular Nucleus,LAC.FD.HT.PV]]
+ VMH=[[BrainRegionLAC_FD_HT_VM|Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM]]
+<img src="http://ahuman.org/svn/ahwiki/images/ext/6f1f0e26e147b046d3567a72e62038bb.jpg" alt=alt="unavailable" style="max-width: 100%;">
 * [http://dkqlgfb5sk2dk.cloudfront.net/content/ajpregu/302/2/R215/F1.large.jpg Glucose-sensing neural network] - see [http://ajpregu.physiology.org/content/302/2/R215 Reference]
-map: ARC=[[BrainRegionLAC_FD_HT_AR|Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR]], DMN=[[BrainRegionLAC_FD_HT_DM|Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM]], LHA=[[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]], PVH=[[BrainRegionLAC_FD_HT_PV|Paraventricular Nucleus,LAC.FD.HT.PV]], VMH=[[BrainRegionLAC_FD_HT_VM|Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM]]
+ map:
-<img src="http://ahuman.org/svn/ahwiki/images/ext/0cd27888f0cfd10857510d32768c3815.jpg" alt="unavailable" style="max-width: 100%;">
+ ARC=[[BrainRegionLAC_FD_HT_AR|Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR]]
+ DMN=[[BrainRegionLAC_FD_HT_DM|Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM]]
+ LHA=[[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]]
+ PVH=[[BrainRegionLAC_FD_HT_PV|Paraventricular Nucleus,LAC.FD.HT.PV]]
+ VMH=[[BrainRegionLAC_FD_HT_VM|Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM]]
+<img src="http://ahuman.org/svn/ahwiki/images/ext/0cd27888f0cfd10857510d32768c3815.jpg" alt=alt="unavailable" style="max-width: 100%;">
 * [http://www.dana.org/uploadedImages/Images/Content_Images/SenBodyFunc2_PR2007_cont.jpg Eating and sleeping to survive] - see [http://www.dana.org/Publications/ReportDetails.aspx?id=44217 Reference]
-map: ARC=[[BrainRegionLAC_FD_HT_AR|Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR]], DMH=[[BrainRegionLAC_FD_HT_DM|Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM]], LHA=[[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]], MPO=[[BrainRegionLAC_FD_HT_MPO|Median Preoptic Nucleus,LAC.FD.HT.MPO]], PVH=[[BrainRegionLAC_FD_HT_PV|Paraventricular Nucleus,LAC.FD.HT.PV]], SCN=[[BrainRegionLAC_FD_HT_SCN|Suprachiasmatic Nucleus,LAC.FD.HT.SCN]], VLPO=[[BrainRegionLAC_FD_HT_VLPO|Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO]], VMH=[[BrainRegionLAC_FD_HT_VM|Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM]]
+ map:
-<img src="http://ahuman.org/svn/ahwiki/images/ext/aaf05c2cb0453d5f112754ade7c03956.jpg" alt="unavailable" style="max-width: 100%;">
+ ARC=[[BrainRegionLAC_FD_HT_AR|Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR]]
+ DMH=[[BrainRegionLAC_FD_HT_DM|Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM]]
+ LHA=[[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]]
+ MPO=[[BrainRegionLAC_FD_HT_MPO|Median Preoptic Nucleus,LAC.FD.HT.MPO]]
+ PVH=[[BrainRegionLAC_FD_HT_PV|Paraventricular Nucleus,LAC.FD.HT.PV]]
+ SCN=[[BrainRegionLAC_FD_HT_SCN|Suprachiasmatic Nucleus,LAC.FD.HT.SCN]]
+ VLPO=[[BrainRegionLAC_FD_HT_VLPO|Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO]]
+ VMH=[[BrainRegionLAC_FD_HT_VM|Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM]]
+<img src="http://ahuman.org/svn/ahwiki/images/ext/aaf05c2cb0453d5f112754ade7c03956.jpg" alt=alt="unavailable" style="max-width: 100%;">
 * [http://www.nature.com/nrendo/journal/v6/n8/images/nrendo.2010.93-f1.jpg Bowels control brain: gut hormones and obesity] - see [http://www.nature.com/nrendo/journal/v6/n8/fig_tab/nrendo.2010.93_F1.html Reference]
-map: AMY=[[BrainCenter|Amygdala,FAM.FT.AM]], ARC=[[BrainRegionLAC_FD_HT_AR|Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR]], DS=Dorsal Striatum,FEC.FT.DST ([[BrainRegionFEC_FT_CN_HD|Caudate Nucleus Head]] (FEC.FT.CN.HD), [[BrainRegionFEC_FT_CN_BD|Caudate Nucleus Body]] (FEC.FT.CN.BD), [[BrainRegionFEC_FT_CN_TL|Caudate Nucleus Tail]] (FEC.FT.CN.TL), [[BrainRegionFEC_FT_PU_LT|Dorsal Putamen Lateral]] (FEC.FT.PU.LT), [[BrainRegionFEC_FT_PU_MED|Dorsal Putamen Medial]] (FEC.FT.PU.MED)), LHA=[[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]], ME=[[BrainRegionTARGET_TEA_ENDOCRINE|Endocrine Glands,TARGET.TEA.ENDOCRINE]], NAc=Accumbens Nucleus,FEC.FT.ACC ([[BrainRegionFEC_FT_ACC_CORE|Nucleus Accumbens Core]] (FEC.FT.ACC.CORE), [[BrainRegionFEC_FT_ACC_SH|Nucleus Accumbens Shell]] (FEC.FT.ACC.SH)), NTS=[[BrainRegionLPC_HL_SOL|Solitary Nucleus,LPC.HL.SOL]], OFC=Orbitofrontal Cortex,NC.AL.OPFC ([[BrainRegionNDM_NC_AL_FPC|Lateral Frontopolar Cortex]] (NDM.NC.AL.FPC), [[BrainRegionNDM_NC_AL_ROFCR|Most Rostral Orbitofrontal Cortex]] (NDM.NC.AL.ROFCR), [[BrainRegionNDM_NC_AL_ROFCS|Sulcal Rostral Orbitofrontal Cortex]] (NDM.NC.AL.ROFCS), [[BrainRegionNDM_NC_AL_ROFCM|Medial Rostral Orbitofrontal Cortex]] (NDM.NC.AL.ROFCM), [[BrainRegionNDM_NC_AL_ROFCL|Lateral Rostral Orbitofrontal Cortex]] (NDM.NC.AL.ROFCL)), PBN=[[BrainRegionLPC_HT_PRF_PB|Parabrachial Nucleus,LPC.HT.PRF.PB]], PVN=[[BrainRegionLAC_FD_HT_PV|Paraventricular Nucleus,LAC.FD.HT.PV]], VMN=[[BrainRegionLAC_FD_HT_VM|Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM]], VTA=[[BrainRegionLMC_MM_VTA|Ventral Tegmental Area,LMC.MM.VTA]]
+ map:
-<img src="http://ahuman.org/svn/ahwiki/images/ext/1550acf4cfac7352ce9d8ba11a39c4e6.jpg" alt="unavailable" style="max-width: 100%;">
+ AMY=[[BrainCenterFAM_FT_AM|Amygdala,FAM.FT.AM]]
+ ARC=[[BrainRegionLAC_FD_HT_AR|Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR]]
+ DS=Dorsal Striatum,FEC.FT.DST (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
+ LHA=[[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]]
+ ME=[[BrainRegionTARGET_TEA_ENDOCRINE|Endocrine Glands,TARGET.TEA.ENDOCRINE]]
+ NAc=Accumbens Nucleus,FEC.FT.ACC (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
+ NTS=[[BrainRegionLPC_HL_SOL|Solitary Nucleus,LPC.HL.SOL]]
+ OFC=Orbitofrontal Cortex,NC.AL.OPFC (see [[BrainCenterNC_AL_OMPFC|Orbitomedial Prefrontal Cortex]])
+ PBN=[[BrainRegionLPC_HT_PRF_PB|Parabrachial Nucleus,LPC.HT.PRF.PB]]
+ PVN=[[BrainRegionLAC_FD_HT_PV|Paraventricular Nucleus,LAC.FD.HT.PV]]
+ VMN=[[BrainRegionLAC_FD_HT_VM|Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM]]
+ VTA=[[BrainRegionLMC_MM_VTA|Ventral Tegmental Area,LMC.MM.VTA]]
+<img src="http://ahuman.org/svn/ahwiki/images/ext/1550acf4cfac7352ce9d8ba11a39c4e6.jpg" alt=alt="unavailable" style="max-width: 100%;">

Difference between revisions of "BrainRegionLAC FD HT AR"

Revision as of 18:56, 28 November 2018

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