BrainRegionNDM NC AL VMPFC

Ventromedial Prefrontal Cortex

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This page covers biological details of component Ventromedial Prefrontal Cortex. Region is part of aHuman target integrated biological model.

• Top-down path to region: Cerebral Cortex -> Anterior Lobe (NC.LOBE.ANT) -> Prefrontal Cortex (NC.AL.PFC) -> Orbitomedial Prefrontal Cortex (NC.AL.OMPFC) -> Medial Prefrontal Cortex (NC.AL.MPFC) -> Ventromedial Prefrontal Cortex (NDM.NC.AL.VMPFC) (see Mind Maps)
• Type: cortex
• Quality: L0
• Brain area: Neocortical Brain - Decision Making Area (NDM)
• Area circuit: Motivatory Associations (MAS)
• Brodmann ID: 11
• Role: cortex.generic
• Function: Ongoing Introverted Attention with Regard to Emotions and Feelings, Reward or Punishment
• Notes to function:
  • lower MPFC, primary connections to limbic and sensory cortices
  • Reward mediated behaviours

(generated)

Components

(generated)

• no child items defined

Connectivity

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Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Role	Reference
FAM	FAM.FT.SEP.DBB	Diagonal Band of Broca	inhibitory-gaba	uncertain	(unknown reference)
FMM	FMM.FT.HC.CA1D	Distal CA1 of Hippocampus	excitatory-glu	uncertain	Gating of medial prefrontal activity by the entorhinal cortex (HC -> MPFC, abstract)
NDM	NDM.FD.TH.PV	Paraventricular Nucleus of Thalamus	excitatory-glu	uncertain	Saccadic Vision (Thalamus -> FrontalCortex, abstract)
	NDM.NC.AL.DLPFCR	Rostral Mid-Dorsolateral Prefrontal Cortex	feedforward-glu	uncertain	Fear regulation (dlPFC -> vmPFC, abstract)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Role	Reference
FAM	FAM.FT.AM.ITC	Intercalated Amygdaloid Nuclei	excitatory-glu	uncertain	(unknown reference)
	FAM.FT.AM.LADL	Dorsolateral Amygdaloid Nucleus	excitatory-glu	uncertain	(unknown reference)

Thirdparty Circuits

(generated)

• Fear regulation - see Reference (CF.FEAR-REG)

B=Basal Amygdaloid Nucleus,FAM.FT.AM.B (see Amygdala)
CE=Central Amygdala,FAM.FT.AM.CEA (see Amygdala)
Hippocampus=Hippocampus,FMM.FT.HC (see Hippocampal Formation)
Hypothalamus=Hypothalamus,FD.HT
ITC=Intercalated Amygdaloid Nuclei,FAM.FT.AM.ITC
LA=Lateral Amygdaloid Nucleus,FAM.FT.AM.LA (see Amygdala)
Striatum=Striatum,FEC.FT.ST (see Basal Ganglia)
dlPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex)
vmPFC=Ventromedial Prefrontal Cortex,NDM.NC.AL.VMPFC

References

(generated)

• https://brmlab.cz/project/brain_hacking/tdcs/pfc