BrainCenterMM RF

Mesencephalic Reticular Formation

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This page covers biological details of component group Mesencephalic Reticular Formation. Component group is part of aHuman target integrated biological model.

• Top-down path to center: Midbrain Mesencephalon -> Mesencephalic Reticular Formation (MM.RF) (see Mind Maps)
• Function:
• Notes to function: Saccades, fixation, gaze holding and vergence. Space-time coordinated rapid eye movements

(generated)

Components

(generated)

Component items:

• Mesencephalic Reticular Formation, Medial Column (MM.RF.MED)
  • Cuneiform Nucleus: Passive coping strategy to novel, painful or threatening stimuli
  • Subcuneiform Nucleus: Initiation of gait, feedback control of saccade accuracy
• Mesencephalic Reticular Formation, Midline Column (MM.RF.MID)
  • Superior Central Raphe Nucleus: Block or temporarily suspend mnemonic processes in the hippocampus; Hallucinations
  • Dorsal Raphe Nucleus: Regulation of sleep and mood
  • Raphe Interpositus Nucleus: Premotor network for saccades

Connectivity

(generated)

Internal Regions Connections:

Source Region	Target Region	Reference
Lateral Habenula Medial Part	Superior Central Raphe Nucleus	Habenula Connections (LHb -> MR, abstract)
	Dorsal Raphe Nucleus	Habenula Connections (LHb -> DR, abstract)
Subfascicular Nucleus of Thalamus	Dorsal Raphe Nucleus	(unknown reference)
Clarke Nucleus	Cuneiform Nucleus	(unknown reference)
Prepositus Nucleus	Subcuneiform Nucleus	(unknown reference)
Gigantocellular Reticular Nucleus	Subcuneiform Nucleus	(unknown reference)
Raphe Interpositus Nucleus	Subcuneiform Nucleus	(unknown reference)
Superficial Superior Colliculus	Raphe Interpositus Nucleus	Horizontal saccades and smooth pursuit movements (SC -> RIP, abstract)
Supplementary Eye Field	Raphe Interpositus Nucleus	Horizontal saccades and smooth pursuit movements (FEFSEF -> RIP, abstract)

External Inbound Center Connections:

Source Center	Reference
Posterior/Dorsal Horn	(unknown reference)
Habenula	Habenula Connections (LHb -> MR, abstract)
Thalamus	(unknown reference)
Medullary Reticular Formation	(unknown reference)
Myelencephalic Motor Nuclei	(unknown reference)
Reflexes Nuclei of Midbrain Mesencephalon	Horizontal saccades and smooth pursuit movements (SC -> RIP, abstract)
Supplementary Motor Cortex	Horizontal saccades and smooth pursuit movements (FEFSEF -> RIP, abstract)

External Outbound Center Connections:

Target Center	Reference
Subthalamus Area	(unknown reference)
Habenula	(unknown reference)
Extended Amygdala	(unknown reference)
Thalamus	(unknown reference)
Medullary Reticular Formation	(unknown reference)
Myelencephalic Parasympathetic Nuclei	(unknown reference)
Metencephalic Motor Nuclei	(unknown reference)
Pontine Reticular Formation	(unknown reference)
Hypothalamus	(unknown reference)