Revision as of 23:38, 26 August 2015

Septal Nuclei

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This page covers biological details of component group Septal Nuclei. Component group is part of aHuman target integrated biological model.

Top-down path to center: Forebrain Telencephalon -> Extended Amygdala (FAM.FT.EXTAM) -> Septal Nuclei (FAM.FT.SEP) (see Mind Maps)
Function: Inhibition of fear and expression of pleasurable responses

(generated)

Components

(generated)

Component items:

Dorsal Septal Nucleus (FAM.FT.SEP.DS)
- Lateral Septal Group (FAM.FT.SEP.LG)
  - Lateral Septal Nucleus (FAM.FT.SEP.LT): promote active stress coping behavior
  - Septohippocampal Nucleus (FAM.FT.SEP.SH): participate in solving conflict between two or more competing goals, defensive circuit
- Medial Septal Group (FAM.FT.SEP.MG)
  - Medial Septal Nucleus (FAM.FT.SEP.MED): affect HC for spatial learning, generation of theta waves
  - Diagonal Band of Broca (FAM.FT.SEP.DBB): involved in generation of theta waves in hippocampus
Posterior Septal Group (FAM.FT.SEP.PG)
- Bed Nucleus of Anterior Commissure (FAM.FT.SEP.BAC): projection to contralateral HC
- Septofimbrial Nucleus (FAM.FT.SEP.SF): afferent to medial habenula, primary input to indirect encoding negative feedback
- Triangular Septal Nucleus (FAM.FT.SEP.TR): afferent to medial habenula, interpeduncular nucleus

(generated)

Internal Regions Connections:

External Connections:

unavailable

External Inbound Center Connections:

Source Center	Reference
Amygdala (FAM.FT.AM)	(unknown reference)
Central Extended Amygdala (FAM.FT.CEAM)	(unknown reference)
Hypothalamus (FD.HT)	Medial mammillary nucleus and theta rhythm (SupraMM -> SEP, abstract)
Hippocampal Formation (FMM.FT.HF)	Connectivity map of the habenula (Hippo -> Septum, abstract)
Pontine Tegmental Nuclei (HT.TG)	(unknown reference)
Locus Coeruleus (LMC.HT.LC)	(unknown reference)
Mesencephalic Reticular Formation (MM.RF)	(unknown reference)
Orbitomedial Prefrontal Cortex (NC.AL.OMPFC)	(unknown reference)

External Outbound Center Connections:

Target Center	Reference
Habenula (FAM.FD.HB)	Connectivity map of the habenula (Septum -> M, abstract)
Hypothalamus (FD.HT)	Cingulate Gyrus (SEP -> HT, abstract)
Cognitive Thalamus (FD.TH.CR)	(unknown reference)
Hippocampal Formation (FMM.FT.HF)	Medial mammillary nucleus and theta rhythm (SEP -> HF, abstract)
Orbitomedial Prefrontal Cortex (NC.AL.OMPFC)	(unknown reference)
Medial Parietal Lobule (NC.MPL)	Medial mammillary nucleus and theta rhythm (SEP -> RSP, abstract)

@@ Line 49: / Line 49: @@
 | [[BrainCenterFD_HT|Hypothalamus]] (FD.HT) || [http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F4.html Medial mammillary nucleus and theta rhythm (SupraMM -> SEP, abstract)]
 |-
-| [[BrainCenterFMM_FT_HF|Hippocampal Formation]] (FMM.FT.HF) || [http://learnmem.cshlp.org/content/14/11/714/F1.expansion Attractor Network in Hippocampus (CA1 -> SEP, abstract)]
+| [[BrainCenterFMM_FT_HF|Hippocampal Formation]] (FMM.FT.HF) || [http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (Hippo -> Septum, abstract)]
 |-
 | [[BrainCenterHT_TG|Pontine Tegmental Nuclei]] (HT.TG) || (unknown reference)
@@ Line 65: / Line 65: @@
 | '''Target Center''' || '''Reference'''
 |-
-| [[BrainCenterFAM_FD_HB|Habenula]] (FAM.FD.HB) || [http://www.scholarpedia.org/article/Habenula Habenula Connections (S -> MHb, abstract)]
+| [[BrainCenterFAM_FD_HB|Habenula]] (FAM.FD.HB) || [http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (Septum -> M, abstract)]
 |-
 | [[BrainCenterFD_HT|Hypothalamus]] (FD.HT) || [http://www.thebrainlabs.com Cingulate Gyrus (SEP -> HT, abstract)]