Revision as of 08:14, 21 September 2015

Insular Cortex

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This page covers biological details of component group Insular Cortex. Component group is part of aHuman target integrated biological model.

Top-down path to center: Cerebral Cortex -> Temporal Lobe (NC.LOBE.TEMP) -> Insular Cortex (NC.INS) (see Mind Maps)
Function: Visceral representation, pain, habits
Notes to function: Interoception, merges tactile and auditory streams

(generated)

Components

(generated)

Component items:

Posterior Insular Cortex (NCP.NC.INS.PIC): Awareness and sensation of pain
Anterior Insular Cortex (NCP.NC.INS.AIC): Risky and moral decision making, articulation
Anterior Temporal Lobe (NCP.NC.INS.HR): Relaying blood pressure and blood chemistry information to brain
Peripaleocortical Claustral (NCP.NC.INS.PPC): Relays proprioception

(generated)

Internal Regions Connections:

unavailable

Source Region	Target Region	Reference
Posterior Insular Cortex (NCP.NC.INS.PIC)	Anterior Insular Cortex (NCP.NC.INS.AIC)	Gustatory sensory system of rat and macaque (Iav -> IadIap, abstract)
	Peripaleocortical Claustral (NCP.NC.INS.PPC)	Gustatory sensory system of rat and macaque (Iav -> IadIap, abstract)

External Connections:

unavailable

External Inbound Center Connections:

Source Center	Sample Link	Reference
Central Extended Amygdala (FAM.FT.CEAM)	FAM.FT.EPF -> NCP.NC.INS.AIC	Gustatory sensory system of rat and macaque (EnP -> Iav, abstract)
Cognitive Thalamus (FD.TH.CR)	NCP.FD.TH.MDC -> NCP.NC.INS.AIC	Amygdalar disruption of prefrontal cortex (TH -> INS, abstract)
Sensory Thalamus (FD.TH.SR)	NSA.FD.TH.VPL -> NCP.NC.INS.HR	Amygdalar disruption of prefrontal cortex (TH -> INS, abstract)
Pontine Reticular Formation (HT.RF)	LPC.HT.PRF.PB -> NCP.NC.INS.PIC	Gustatory sensory system of rat and macaque (PB -> Gud, abstract)
Rhinal Cortex (NC.PHA.RH)	NSA.NC.PH.PIR -> NCP.NC.INS.AIC	Gustatory sensory system of rat and macaque (PiR -> Iav, abstract)
Superior Parietal Lobule (NC.SPL)	NPE.NC.SPL.SA -> NCP.NC.INS.PIC	(unknown reference)
Superior Temporal Gyrus (NC.STG)	NCP.NC.TPC -> NCP.NC.INS.AIC	Directed Effort Network (tPole -> Insula, abstract)

External Outbound Center Connections:

Target Center	Sample Link	Reference
Amygdala (FAM.FT.AM)	NCP.NC.INS.PIC -> FAM.FT.AM.BM	Afferent pain pathways (Insula -> AMY, abstract)
Retrosubicular Area (FMM.NC.PHA.RS)	NCP.NC.INS.PPC -> FMM.NC.PH.PRS	(unknown reference)
Anterior Cingulate Area (NC.ACG)	NCP.NC.INS.AIC -> NDM.NC.AL.VACG	Amygdalar disruption of prefrontal cortex (INS -> ACG, abstract)
Lateral Prefrontal Cortex (NC.AL.LPFC)	NCP.NC.INS.AIC -> NDM.NC.AL.IPG	Directed Effort Network (Insula -> fPole, abstract)
Orbitomedial Prefrontal Cortex (NC.AL.OMPFC)	NCP.NC.INS.PPC -> NDM.NC.AL.FPC	Amygdalar disruption of prefrontal cortex (INS -> MPFC, abstract)
Rhinal Cortex (NC.PHA.RH)	NCP.NC.INS.AIC -> FMM.NC.PH.PER	Gustatory sensory system of rat and macaque (Iav -> PrC, abstract)

@@ Line 67: / Line 67: @@
 | '''Target Center''' || '''Sample Link''' || '''Reference'''
 |-
-| [[BrainCenterFAM_FT_AM|Amygdala]] (FAM.FT.AM) || [[BrainRegionNCP_NC_INS_PIC|NCP.NC.INS.PIC]] -> [[BrainRegionFAM_FT_AM_BM|FAM.FT.AM.BM]]||(unknown reference)
+| [[BrainCenterFAM_FT_AM|Amygdala]] (FAM.FT.AM) || [[BrainRegionNCP_NC_INS_PIC|NCP.NC.INS.PIC]] -> [[BrainRegionFAM_FT_AM_BM|FAM.FT.AM.BM]]||[http://www.nature.com/nrn/journal/v14/n7/fig_tab/nrn3516_F2.html Afferent pain pathways (Insula -> AMY, abstract)]
 |-
 | [[BrainCenterFMM_NC_PHA_RS|Retrosubicular Area]] (FMM.NC.PHA.RS) || [[BrainRegionNCP_NC_INS_PPC|NCP.NC.INS.PPC]] -> [[BrainRegionFMM_NC_PH_PRS|FMM.NC.PH.PRS]]||(unknown reference)