BrainRegionLPC SC VH ONF

Onuf's Nucleus

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This page covers biological details of component Onuf's Nucleus. Region is part of aHuman target integrated biological model.

• Top-down path to region: Spinal Cord -> Anterior/Ventral Horn (SC.VH) -> Lamina IX (SC.VH.L9) -> Onuf's Nucleus (LPC.SC.VH.ONF) (see Mind Maps)
• Type: nucleus
• Brain area: Lower Brain - Peripheral Control Area
• Role: flexor.nucleus
• Function: Maintenance of urination and defecation, muscular contraction during orgasm
• Notes to function: From Barrington's Nucleus

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Components

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• no child items defined

Connectivity

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Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
LAC	LAC.FD.HT.PV	Paraventricular Nucleus	excitatory-glu	(unknown reference)
	LAC.HT.BR	Barrington's Nucleus	excitatory-glu	Schematic overview of spinobulbospinal micturition reflex pathway (BAR -> ONF)
LRC	LRC.HL.RA	Retroambigualis Nucleus	excitatory-glu	(unknown reference)
NMA	NMA.NC.MC	Motor Cortex	excitatory-glu	Cerebellum functional divisions (CTX -> SCM, abstract)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
TEA	TARGET.TEA.GENITALIA	Genitalia	bulbospongiosus-muscle	(unknown reference)
	TARGET.TEA.RECTUM	Rectum	corrugator-cutis-ani-muscle	(unknown reference)
	TARGET.TEA.URETER	Ureter	external-urethral-sphincter-female	(unknown reference)

Thirdparty Circuits

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• Physiology and pathophysiology of lower urinary tract - see Reference

• Schematic overview of spinobulbospinal micturition reflex pathway - see Reference

References

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• http://www.intechopen.com/books/computational-intelligence-in-electromyography-analysis-a-perspective-on-current-applications-and-future-challenges/sphincter-emg-for-diagnosing-multiple-system-atrophy-and-related-disorders
• http://jp.physoc.org/content/557/1/287/F9.expansion.html