BrainRegionLPC HL AMB

Ambiguus Nucleus

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This page covers biological details of component Ambiguus Nucleus. Region is part of aHuman target integrated biological model.

• Top-down path to region: Hindbrain Myelencephalon -> Myelencephalic Motor Nuclei (HL.MN) -> Expiratory Center (HL.RC) -> Ambiguus Nucleus (LPC.HL.AMB) (see Mind Maps)
• Type: nucleus
• Quality: L0
• Brain area: Lower Brain - Peripheral Control Area (LPC)
• Area circuit: Breathing and Swallowing Motor (ABS)
• Role: flexor.nucleus
• Function: Control muscles of the soft palate, pharynx, and larnyx
• Notes to function:
  • On par with VGM, speech
  • speech and swallowing, parasympathetic, innervates the cardiac ganglia to contribute to the control of heart rate

(generated)

Components

(generated)

• no child items defined

Connectivity

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Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
LMC	LMC.MM.PAG	Periaqueductal Gray Matter	modulatory-enk	(unknown reference)
LPC	LPC.HL.SOL	Solitary Nucleus	excitatory-glu	(unknown reference)
LRC	LRC.HL.RA	Retroambigualis Nucleus	excitatory-glu	(unknown reference)
	LRC.HT.PRF.CRF	Caudal Pontine Reticular Nucleus	excitatory-glu	Vocal Control (RF -> NucleusAmbiguus, abstract)
NMA	NMA.NC.MC	Motor Cortex	excitatory-glu	(unknown reference)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
TEA	TARGET.TEA.FEEDER	Mouth feeder	inferior-pharyngeal-constrictor-muscle	(unknown reference)
	TARGET.TEA.LUNG	Lung	stylopharyngeus-muscle	(unknown reference)
	TARGET.TEA.SPEAKER	Mouth speaker	arytenoid-muscle	(unknown reference)
TSA	TARGET.TSA.NOSE	Nose	nose-salpingopharyngeus	(unknown reference)

Thirdparty Circuits

(generated)

• Vocal Control - see Reference (CM.VOCAL-CONTROL)

A1=Primary Auditory Cortex,NSA.NC.TTG.A1
Broca=Broca's Area,NPE.NC.PFC.BRA (see Lateral Prefrontal Cortex)
M2=Supplementary Motor Cortex,NMA.NC.SMC
MotorV=Trigeminal Motor Nucleus,LPC.HT.TRM
MotorVII=Facial Motor Nucleus,LPC.HT.FCM
NucleusAmbiguus=Ambiguus Nucleus,LPC.HL.AMB
NucleusXII=Hypoglossal Motor Nucleus,LPC.HL.HYG
Premotor24=Ventral Anterior Cingulate Area,NDM.NC.AL.VACG
RF=Pontine Reticular Formation,HT.RF
Wernike=Wernicke's area A4,NSA.NC.STG.A4

References

(generated)

• http://www.frontiersin.org/neuroanatomy/10.3389/fnana.2011.00034/full