BrainRegionFAM FT SEP MED

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Medial Septal Nucleus

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This page covers biological details of component Medial Septal Nucleus. Region is part of aHuman target integrated biological model.

  • *Top-down path to region*: Forebrain Telencephalon -> Extended Amygdala (FAM.FT.EXTAM) -> Septal Nucleus (FAM.FT.SEP) -> Dorsal Septal Nucleus (FAM.FT.SEP.DS) -> Medial Septal Group (FAM.FT.SEP.MG) -> Medial Septal Nucleus (FAM.FT.SEP.MED) (see Mind Maps)
  • *Type*: nucleus
  • *Brain area*: Forebrain - Affective Motivations Area
  • *Role*: relay
  • *Function*: affect HC for spatial learning, generation of theta waves
  • *Notes to function*: output nucleus; projections from AM and HC overlap; control theta rythm and exprolatory behavior; from/to MFB to fornix fimbria

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Components

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Connectivity

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FAM.FT.SEP.MED.dot.png

  • Inbound Region Connections:*

|| *Source Area* || *Source Region* || *Source Name* || *Type* || *Reference* || || FMM || BrainRegionFMM_FT_HC_CA1D FMM.FT.HC.CA1D || Distal CA1 of Hippocampus || excitatory-glu || [Attractor Network in Hippocampus (CA1 -> SEP, abstract)] || || LAC || BrainRegionLAC_FD_HT_SUM LAC.FD.HT.SUM || Supramammillary Nucleus || excitatory-glu || [Medial mammillary nucleus and theta rhythm (SupraMM -> SEP, abstract)] ||

  • Outbound Region Connections:*

|| *Target Area* || *Target Region* || *Target Name* || *Type* || *Reference* || || FEC || BrainRegionFEC_FD_TH_PF FEC.FD.TH.PF || Parafascicular Nucleus of Thalamus || modulatory-ach || (unknown reference) || || FMM || BrainRegionFMM_FD_MB_LMB FMM.FD.MB.LMB || Lateral Mammillary Nucleus || modulatory-ach || [Cingulate Gyrus (SEP -> HT, abstract)] || || || FMM.FD.MB.MMB || Medial Mammillary Nucleus || inhibitory-gaba || [Cingulate Gyrus (SEP -> HT, abstract)] || || NCP || BrainRegionNCP_NC_MPL_RSC NCP.NC.MPL.RSC || Retrosplenial Cortex || modulatory-ach || [Medial mammillary nucleus and theta rhythm (SEP -> RSP, abstract)] || || NDM || BrainRegionNDM_FD_TH_MDM NDM.FD.TH.MDM || Medial Mediodorsal Nucleus of Thalamus || modulatory-ach || [Thalamocortical relationships (s1MD -> MD, abstract)] ||

Thirdparty Circuits

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References

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