Medial Mammillary Nucleus

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This page covers biological details of component Medial Mammillary Nucleus. Region is part of aHuman target integrated biological model.

Top-down path to region: Forebrain Diencephalon -> Hypothalamus (FD.HT) -> Mammillary Body (FD.MB) -> Medial Mammillary Nucleus (FMM.FD.MB.MMB) (see Mind Maps)
Type: nucleus
Brain area: Forebrain - Memory Management Area
Role: processor.memory.space
Function: Relay for impulses coming from AM and HC
Notes to function: Memory, recognition, spatial awareness, and interpreting the context of events

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Components

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Component items:

Connectivity

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FMM.FD.MB.MMB.dot.png

Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
FAM	FAM.FT.SEP.DBB	Diagonal Band of Broca	inhibitory-gaba	Cingulate Gyrus (SEP -> HT, abstract)
	FAM.FT.SEP.MED	Medial Septal Nucleus	inhibitory-gaba	Cingulate Gyrus (SEP -> HT, abstract)
FMM	FMM.FT.HC.CA1P	Proximal CA1 of Hippocampus	excitatory-glu	Feeling (HC -> HT, abstract)
	FMM.FT.HF.SUBD	Distal Subiculum	excitatory-glu	Principal Connections of Hippocampus (HC -> MB, abstract)
	FMM.FT.HF.SUBP	Proximal Subiculum	excitatory-glu	Principal Connections of Hippocampus (HC -> MB, abstract)
	FMM.NC.PH.MEC	Medial Entorhinal Cortex	excitatory-glu	Mammillary bodies: two memory systems in one (MedialEC -> MMB, abstract)
	FMM.NC.PH.PRS	Presubiculum	excitatory-glu	Attractor Network in Hippocampus (PRESUB -> MBIN)
LAC	LAC.FD.HT.TBM	Tuberomammillary Nucleus	excitatory-glu	Mammillary bodies: two memory systems in one (TuberoMM -> MMB, abstract)
LMC	LMC.MM.RF.SUC	Superior Central Raphe Nucleus	modulatory-5ht	(unknown reference)
	LMC.MM.VTA	Ventral Tegmental Area	modulatory-da	Mammillary bodies: two memory systems in one (VTN -> MMB)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
FMM	FMM.FD.TH.AV	Anteroventral Nucleus	excitatory-glu	Mammillary bodies: two memory systems in one (MMB -> AVTH)
LLC	LLC.HT.PN.RSP	Rostral Pontine Nucleus	excitatory-glu	Prefrontal Cortex (PFC) in emotional behavior (HT -> PN, abstract)
	LLC.HT.PRF.PDT	Pontine Reticulotegmental Nucleus	excitatory-glu	Mammillary Body (MMB -> RTG)
NCP	NCP.FD.TH.AM	Anteromedial Nucleus	excitatory-glu	Mammillary bodies: two memory systems in one (MMB -> AMTH)