BrainCenterMM RF
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Mesencephalic Reticular Formation
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This page covers biological details of component group Mesencephalic Reticular Formation. Component group is part of aHuman target integrated biological model.
- Top-down path to center: Midbrain Mesencephalon -> Mesencephalic Reticular Formation (MM.RF) (see Mind Maps)
- Function:
- Notes to function: Saccades, fixation, gaze holding and vergence. Space-time coordinated rapid eye movements
(generated)
Components
(generated)
Component items:
- Mesencephalic Reticular Formation, Medial Column (MM.RF.MED)
- Cuneiform Nucleus (LLC.MM.CNF): Passive coping strategy to novel, painful or threatening stimuli
- Subcuneiform Nucleus (LLC.MM.SCNF): Initiation of gait, feedback control of saccade accuracy
- Mesencephalic Reticular Formation, Midline Column (MM.RF.MID)
- Superior Central Raphe Nucleus (LMC.MM.RF.SUC): Block or temporarily suspend mnemonic processes in the hippocampus; Hallucinations
- Dorsal Raphe Nucleus (LMC.MM.RP.DRN): Regulation of sleep and mood
- Raphe Interpositus Nucleus (LRC.MM.RP.RIP): Premotor network for saccades
- Raphe Nucleus Linearis (LMC.HP.RP.LI): Release of 5-HT was only obtained on stimulation of this nucleus
Connectivity
(generated)
Internal Regions Connections:
| Source Region | Target Region | Reference |
| Raphe Nucleus Linearis (LMC.HP.RP.LI) | Dorsal Raphe Nucleus (LMC.MM.RP.DRN) | (unknown reference) |
| Raphe Interpositus Nucleus (LRC.MM.RP.RIP) | Subcuneiform Nucleus (LLC.MM.SCNF) | (unknown reference) |
External Connections:
External Inbound Center Connections:
| Source Center | Reference |
| Posterior/Dorsal Horn (BMA.SC.PH) | (unknown reference) |
| Habenula (FAM.FD.HB) | Habenula Connections (LHb -> MR, abstract) |
| Cognitive Thalamus (FD.TH.CR) | (unknown reference) |
| Myelencephalic Motor Nuclei (HL.MN) | (unknown reference) |
| Medullary Reticular Formation (HL.RF) | (unknown reference) |
| Pontine Tegmental Nuclei (HT.TG) | Both LHb and MHb control the dopaminergic and serotonergic systems (IPN -> DRN) |
| Reflexes Nuclei of Midbrain Mesencephalon (MM.REF) | Horizontal saccades and smooth pursuit movements (SC -> RIP, abstract) |
| Supplementary Motor Cortex (NMA.NC.SMC) | Horizontal saccades and smooth pursuit movements (FEFSEF -> RIP, abstract) |
External Outbound Center Connections:
| Target Center | Reference |
| Habenula (FAM.FD.HB) | (unknown reference) |
| Septal Nuclei (FAM.FT.SEP) | (unknown reference) |
| Hypothalamus (FD.HT) | (unknown reference) |
| Cognitive Thalamus (FD.TH.CR) | (unknown reference) |
| Subthalamus Area (FEC.FD.STA) | (unknown reference) |
| Myelencephalic Parasympathetic Nuclei (HL.PSN) | (unknown reference) |
| Medullary Reticular Formation (HL.RF) | (unknown reference) |
| Metencephalic Motor Nuclei (HT.MN) | (unknown reference) |
| Pontine Reticular Formation (HT.RF) | (unknown reference) |
