BrainRegionFMM FD MB MMB
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Medial Mammillary Nucleus
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This page covers biological details of component Medial Mammillary Nucleus. Region is part of aHuman target integrated biological model.
- Top-down path to region: Forebrain Diencephalon -> Hypothalamus (HTA.FD.HT) -> Mammillary Body (FD.MB) -> Medial Mammillary Nucleus (FMM.FD.MB.MMB) (see Mind Maps)
- Type: nucleus
- Brain area: Forebrain - Memory Management Area
- Role: relay
- Function: Relay for impulses coming from AM and HC
- Notes to function: Memory, recognition, spatial awareness, and interpreting the context of events
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Components
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Component items:
- Mediolateral Mammillary Nucleus
- Medial Part of Medial Mammillary Nucleus
Connectivity
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Inbound Region Connections:
Source Area | Source Region | Source Name | Type | Reference |
FAM | FAM.FT.SEP.DBB | Diagonal Band of Broca | inhibitory-gaba | Cingulate Gyrus (SEP -> HT, abstract) |
FAM.FT.SEP.MED | Medial Septal Nucleus | inhibitory-gaba | Cingulate Gyrus (SEP -> HT, abstract) | |
FMM | FMM.FT.HF.SUBD | Distal Subiculum | excitatory-glu | Mammillary bodies: two memory systems in one (SUB -> MMB, abstract) |
FMM.FT.HF.SUBP | Proximal Subiculum | excitatory-glu | Mammillary bodies: two memory systems in one (SUB -> MMB, abstract) | |
FMM.NC.PH.MEC | Medial Entorhinal Cortex | excitatory-glu | Mammillary bodies: two memory systems in one (MedialEC -> MMB, abstract) | |
FMM.NC.PH.PRS | Presubiculum | excitatory-glu | Attractor Network in Hippocampus (PRESUB -> MBIN) | |
LAC | LAC.FD.HT.LTN | Lateral Hypothalamic Nucleus | excitatory-glu | (unknown reference) |
LAC.FD.HT.PN | Posterior Hypothalamic Nucleus | excitatory-glu | (unknown reference) | |
LMC | LMC.HP.TG.VTG | Ventral Tegmental Nucleus | excitatory-glu | (unknown reference) |
LMC.MM.RF.SUC | Superior Central Raphe Nucleus | modulatory-5ht | (unknown reference) | |
LMC.MM.VTA | Ventral Tegmental Area | modulatory-da | Mammillary bodies: two memory systems in one (VTN -> MMB) |
Outbound Region Connections:
Target Area | Target Region | Target Name | Type | Reference |
FMM | FMM.FD.TH.AV | Anteroventral Nucleus | excitatory-glu | Mammillary bodies: two memory systems in one (MMB -> AVTH) |
LLC | LLC.HP.PN.RP | Rostral Pontine Nucleus | excitatory-glu | Prefrontal Cortex (PFC) in emotional behavior (HT -> PN, abstract) |
LLC.HP.PRF.PDT | Pontine Reticulotegmental Nucleus | excitatory-glu | Mammillary Body (MMB -> RTG) |
Thirdparty Circuits
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- Mammillary Body (unknown reference)
References
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- http://learnmem.cshlp.org/content/18/6/384/F1.expansion.html
- http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F4.html
- http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F2.html
- http://neurondevelopment.org/hippocampal-development
- http://highered.mcgraw-hill.com/sites/dl/free/0071402357/156721/figure350_1.html
- http://learnmem.cshlp.org/content/14/11/714/F1.expansion