BrainRegionFMM NC PH LEC

Lateral Entorhinal Cortex

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This page covers biological details of component Lateral Entorhinal Cortex. Region is part of aHuman target integrated biological model.

• Top-down path to region: Cortex -> Parahippocampal Lobe (NC.LOBE.PH) -> Anterior Parahippocampal Gyrus (FMM.NC.PHA) -> Rhinal Cortex (NC.PHA.RH) -> Entorhinal Cortex (FMM.NC.PH.ET) -> Lateral Entorhinal Cortex (FMM.NC.PH.LEC) (see Mind Maps)
• Type: cortex
• Brain area: Forebrain - Memory Management Area
• Brodmann ID: 28
• Role: processor
• Function: Memory consolidation, emotioncal aspects
• Notes to function: non-spatial input to HC; process information about individual items and locations based on a local frame of reference, primarily using external sensory input; it provides the hippocampus with information about content of experience

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Components

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Connectivity

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Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
FAM	FAM.FD.TH.PT	Paratenial Nucleus of Thalamus	excitatory-glu	[of Diencephalon to Recognition Memory (MID -> EC, abstract)]
	FAM.FT.AM.BP	Parvicellular Basal Amygdaloid Nucleus	excitatory-glu	[Connections of Hippocampus (AM -> EC, abstract)]
FMM	FMM.FT.HF.SUBD	Distal Subiculum	excitatory-glu	[Network in Hippocampus (SUB -> EC, abstract)]
	FMM.NC.PH.PER	Perirhinal Cortex	feedforward-glu	[Path to Hippocampus (PRPH -> ER, abstract)]
LMC	LMC.MM.VTA	Ventral Tegmental Area	modulatory-da	[Novelty, Motivational Salience, and Reward to Control Attention and Learning (VTA -> EC, abstract)]
LPC	LPC.FD.TH.PV	Paraventricular Nucleus of Thalamus	excitatory-glu	[of Diencephalon to Recognition Memory (MID -> EC, abstract)]
NSA	NSA.NC.IT.TE	Inferotemporal Cortex	feedforward-glu	[Spatial Processing Network (ITCortex -> EnthCortex, abstract)]
	NSA.NC.PH.PIR	Piriform Cortex	feedforward-glu	[model of cortico-hippocampal formation with subcortical projections for motor actions (PC -> EC, abstract)]
	NSA.NC.STG.A3	Wernicke's area A3	feedforward-glu	(unknown reference)
	NSA.NC.STG.A4	Wernicke's area A4	feedforward-glu	(unknown reference)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
FAM	FAM.FT.AM.AB	Accessory Basal Amygdaloid Nucleus	excitatory-glu	[model of hippocampal formation anatomy (EC -> Amyg, abstract)]
FEC	FEC.FT.ACC.CORE	Nucleus Accumbens Core	excitatory-glu	[Accumbens (EC -> NACC, abstract)]
FMM	FMM.FT.HC.CA1D	Distal CA1 of Hippocampus	excitatory-glu	[projections in the hippocampus (ET -> CA1, abstract)]
	FMM.FT.HC.CA2	Dorsolateral Cornu Ammonis of Hippocampus	excitatory-glu	[and its network (EC -> HC, abstract)]
	FMM.FT.HC.DG	Dentate Gyrus	excitatory-glu	[projections in the hippocampus (ET -> DG, abstract)]
	FMM.FT.HF.SUBP	Proximal Subiculum	excitatory-glu	[Path to Hippocampus (ER -> H, abstract)]
NDM	NDM.FD.TH.MDM	Medial Mediodorsal Nucleus of Thalamus	excitatory-glu	[of Diencephalon to Recognition Memory (EC -> MDmc, abstract)]

Thirdparty Circuits

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References

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