Median Preoptic Nucleus

@@Home -> BiologicalLifeResearch -> BrainAreaLAC -> BrainRegionLAC_FD_HT_MPO

This page covers biological details of component Median Preoptic Nucleus. Region is part of aHuman target integrated biological model.

Top-down path to region: Forebrain Diencephalon -> Hypothalamus (FD.HT) -> Anterior Hypothalamus Area (LAC.FD.HT.AHT) -> Chiasmatic Area (LAC.FD.HT.CHS) -> Preoptic Nucleus (LAC.FD.HT.PO) -> Median Preoptic Nucleus (LAC.FD.HT.MPO) (see Mind Maps)
Type: nucleus
Brain area: Lower Brain - Autonomous Control Area
Role: processor.autonomic
Function: generates thirst
Notes to function: Drinking decreases noradrenaline release in median preoptic nucleus

(generated)

Components

(generated)

Connectivity

(generated)

LAC.FD.HT.MPO.dot.png

Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
FAM	FAM.FT.AM.MPD	Medial Posterior Dorsal Amygdaloid Nucleus	inhibitory-gaba	Role for serotonin in moral behavior (AMY -> HYP, abstract)
FMM	FMM.FT.HC.CA1D	Distal CA1 of Hippocampus	excitatory-glu	Feeling (HC -> HT, abstract)
LAC	LAC.FD.HT.DM	Dorsomedial Hypothalamic Nucleus	excitatory-glu	Eating and sleeping to survive (DMH -> MPO)
	LAC.FD.HT.PRM	Premammillary Nucleus	excitatory-glu	(unknown reference)
	LAC.FD.HT.SCN	Suprachiasmatic Nucleus	excitatory-glu	Intrahypothalamic connections important for neural control of food intake and energy balance (SCH -> MPOA)
	LAC.HL.TGS.PE5	Peritrigeminal Nucleus	excitatory-glu	(unknown reference)
NDM	NDM.FD.TH.PV	Paraventricular Nucleus of Thalamus	excitatory-glu	(unknown reference)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
FAM	FAM.FD.TH.PT	Paratenial Nucleus of Thalamus	excitatory-glu	(unknown reference)
LAC	LAC.FD.HT.AH	Anterior Hypothalamic Nucleus	excitatory-glu	Intrahypothalamic connections important for neural control of food intake and energy balance (MPOA -> AH)
	LAC.FD.HT.PV	Paraventricular Nucleus	excitatory-glu	Intrahypothalamic connections important for neural control of food intake and energy balance (MPOA -> PA)
	LAC.FD.HT.SO	Supraoptic Nucleus	excitatory-glu	Intrahypothalamic connections important for neural control of food intake and energy balance (MPOA -> SON)
LMC	LMC.HL.RP.OB	Raphe Obscurus Nucleus	excitatory-glu	(unknown reference)