Revision as of 01:18, 16 June 2015

Nucleus Accumbens Shell

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This page covers biological details of component Nucleus Accumbens Shell. Region is part of aHuman target integrated biological model.

• *Top-down path to region*: Forebrain Telencephalon -> Basal Ganglia (BGA.FT.BG) -> Striatum (BGA.FT.ST) -> Ventral Striatum (BGA.FT.VST) -> Accumbens Nucleus (FEC.FT.ACC) -> Nucleus Accumbens Shell (FEC.FT.ACC.SH) (see Mind Maps)
• *Type*: nucleus
• *Brain area*: Forebrain - Execution Control Area
• *Role*: relay
• *Function*: cognitive processing of motivational salience (wanting) as well as reward and reinforcement effects

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Components

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Connectivity

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• Inbound Region Connections:*

|| *Source Area* || *Source Region* || *Source Name* || *Type* || *Reference* || || FEC || BrainRegionFEC_FT_SNC_MED FEC.FT.SNC.MED || Substantia Nigra Pars Compacta Medial || modulatory-da || (unknown reference) || || LMC || BrainRegionLMC_MM_VTA LMC.MM.VTA || Ventral Tegmental Area || modulatory-da || [Craving (VTA -> NACC, abstract)] || || NCP || BrainRegionNCP_NC_MPL_PSCG NCP.NC.MPL.PSCG || Posterior Cingulate Cortex || excitatory-glu || (unknown reference) || || NDM || BrainRegionNDM_NC_AL_VACG NDM.NC.AL.VACG || Ventral Anterior Cingulate Area || excitatory-glu || [Global visual system (FrontalCortex -> BGA, abstract)] ||

• Outbound Region Connections:*

|| *Target Area* || *Target Region* || *Target Name* || *Type* || *Reference* || || FEC || BrainRegionFEC_FT_IPAC_LT FEC.FT.IPAC.LT || Lateral Interstitial Anterior Commissural Nucleus || inhibitory-gaba || (unknown reference) || || || FEC.FT.VP.VM || Ventral Pallidum Ventromedial || inhibitory-gaba || [Craving (NACC -> VPAL, abstract)] || || LAC || BrainRegionLAC_FD_HT_LTN LAC.FD.HT.LTN || Lateral Hypothalamic Nucleus || inhibitory-gaba || (unknown reference) || || LMC || BrainRegionLMC_FT_NBM LMC.FT.NBM || Basal Nucleus of Meynert || inhibitory-gaba || [Affective basal ganglia circuit (NACC -> nBM, abstract)] ||

Thirdparty Circuits

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References

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