Revision as of 09:22, 15 July 2015

Nucleus Accumbens Core

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This page covers biological details of component Nucleus Accumbens Core. Region is part of aHuman target integrated biological model.

Top-down path to region: Forebrain Telencephalon -> Basal Ganglia (BGA.FT.BG) -> Striatum (BGA.FT.ST) -> Ventral Striatum (BGA.FT.VST) -> Accumbens Nucleus (FEC.FT.ACC) -> Nucleus Accumbens Core (FEC.FT.ACC.CORE) (see Mind Maps)
Type: nucleus
Brain area: Forebrain - Execution Control Area
Role: relay
Function: cognitive processing of motor function related to reward and reinforcement; encodes new motor programs which facilitate acquisition of given reward in future

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Components

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FEC.FT.ACC.CORE.dot.png

Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
FAM	FAM.FD.TH.PT	Paratenial Nucleus of Thalamus	excitatory-glu	(unknown reference)
	FAM.FT.AM.BP	Parvicellular Basal Amygdaloid Nucleus	excitatory-glu	Amygdala and its network (BLN -> NACC, abstract)
FMM	FMM.FD.TH.RH	Rhomboidal Nucleus of Thalamus	excitatory-glu	(unknown reference)
	FMM.FT.HF.SUBD	Distal Subiculum	excitatory-glu	Nucleus Accumbens (SUB -> NACC, abstract)
	FMM.FT.HF.SUBP	Proximal Subiculum	excitatory-glu	Nucleus Accumbens (SUB -> NACC, abstract)
	FMM.NC.PH.LEC	Lateral Entorhinal Cortex	excitatory-glu	Nucleus Accumbens (EC -> NACC, abstract)
	FMM.NC.PH.PAS	Parasubiculum	excitatory-glu	Nucleus Accumbens (PAS -> NACC, abstract)
	FMM.NC.PH.PER	Perirhinal Cortex	excitatory-glu	Nucleus Accumbens (PRR -> NACC, abstract)
LPC	LPC.FD.TH.PV	Paraventricular Nucleus of Thalamus	excitatory-glu	(unknown reference)
NDM	NDM.NC.AL.FPC	Lateral Frontopolar Cortex	excitatory-glu	Affective basal ganglia circuit (OMPFC -> NACC, abstract)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
FEC	FEC.FT.SNC.MED	Substantia Nigra Pars Compacta Medial	inhibitory-gaba	(unknown reference)
	FEC.FT.VP.DL	Ventral Pallidum Dorsolateral	inhibitory-gaba	Craving (NACC -> VPAL, abstract)
LMC	LMC.MM.VTA	Ventral Tegmental Area	inhibitory-gaba	Reward circuit of human brain (NACC -> VTA, abstract)

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 |  || [[BrainRegionFAM_FT_AM_BP|FAM.FT.AM.BP]] || Parvicellular Basal Amygdaloid Nucleus || excitatory-glu || [http://www.surgicalneurologyint.com/article.asp?issn=2152-7806;year=2012;volume=3;issue=2;spage=40;epage=46;aulast=Langevin Amygdala and its network (BLN -> NACC, abstract)]
 |-
-| [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_FD_TH_RH|FEC.FD.TH.RH]] || Rhomboidal Nucleus of Thalamus || excitatory-glu || (unknown reference)
+| [[BrainAreaFMM|FMM]] || [[BrainRegionFMM_FD_TH_RH|FMM.FD.TH.RH]] || Rhomboidal Nucleus of Thalamus || excitatory-glu || (unknown reference)
 |-
-| [[BrainAreaFMM|FMM]] || [[BrainRegionFMM_FT_HF_SUBD|FMM.FT.HF.SUBD]] || Distal Subiculum || excitatory-glu || [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/nucleus-accumbens.jpg Nucleus Accumbens (SUB -> NACC, abstract)]
+|  || [[BrainRegionFMM_FT_HF_SUBD|FMM.FT.HF.SUBD]] || Distal Subiculum || excitatory-glu || [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/nucleus-accumbens.jpg Nucleus Accumbens (SUB -> NACC, abstract)]
 |-
 |  || [[BrainRegionFMM_FT_HF_SUBP|FMM.FT.HF.SUBP]] || Proximal Subiculum || excitatory-glu || [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/nucleus-accumbens.jpg Nucleus Accumbens (SUB -> NACC, abstract)]