Difference between revisions of "BrainRegionLMC HT TG PPN"

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<pre style="color: green">Pedunculopontine Tegmental Nuclei</pre>
 
<pre style="color: green">Pedunculopontine Tegmental Nuclei</pre>
 
@@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainAreaLMC]] -> [[BrainRegionLMC_HT_TG_PPN]]
 
@@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainAreaLMC]] -> [[BrainRegionLMC_HT_TG_PPN]]
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* '''Top-down path to region''': Hindbrain Metencephalon -> [[BrainCenterHT_TG|Pontine Tegmental Nuclei]] (HT.TG) -> [[BrainRegionLMC_HT_TG_PPN|Pedunculopontine Tegmental Nuclei]] (LMC.HT.TG.PPN) (see [[OverallMindMaps|Mind Maps]])
 
* '''Top-down path to region''': Hindbrain Metencephalon -> [[BrainCenterHT_TG|Pontine Tegmental Nuclei]] (HT.TG) -> [[BrainRegionLMC_HT_TG_PPN|Pedunculopontine Tegmental Nuclei]] (LMC.HT.TG.PPN) (see [[OverallMindMaps|Mind Maps]])
 
* '''Type''': nucleus
 
* '''Type''': nucleus
* '''Brain area''': [[BrainAreaLMC|Lower Brain - Modulatory Contol Area]]
+
* '''Quality''': L0
 +
* '''Brain area''': [[BrainAreaLMC|Lower Brain - Modulatory Contol Area]] (LMC)
 +
* '''Area circuit''': Acetylcholine - PNS Actions and CNS plasticity, arousal and reward (ACH)
 
* '''Role''': processor.autonomic
 
* '''Role''': processor.autonomic
 
* '''Function''': Provide sensory feedback to cerebral cortex; modulatory
 
* '''Function''': Provide sensory feedback to cerebral cortex; modulatory
* '''Notes to function''': contains Rostral (Pars dissipata, anterior, dissipated subnucleus, GABA), Caudal (Pars compacta, anterior, compact subnucleus, ACh)
+
* '''Notes to function''':  
 +
** contains Rostral (Pars dissipata, anterior, dissipated subnucleus, GABA), Caudal (Pars compacta, anterior, compact subnucleus, ACh)
 
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= Components =
 
= Components =
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{| class=wikitable width=80%
 
{| class=wikitable width=80%
| '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Reference'''
+
| '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Role''' || '''Reference'''
 
|-
 
|-
| [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_FT_VP_VM|FEC.FT.VP.VM]] || Ventral Pallidum Ventromedial || inhibitory-gaba || [http://www.impulsecontroldisorders.org/html/cravings.html Combining Novelty, Motivational Salience, and Reward to Control Attention and Learning (VPAL -> PPTG, abstract)]
+
| [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_FT_VP_VM|FEC.FT.VP.VM]] || Ventral Pallidum Ventromedial || inhibitory-gaba || uncertain ||[http://www.impulsecontroldisorders.org/html/cravings.html Combining Novelty, Motivational Salience, and Reward to Control Attention and Learning (VPAL -> PPTG, abstract)]
 
|}
 
|}
  
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{| class=wikitable width=80%
 
{| class=wikitable width=80%
| '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Reference'''
+
| '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Role''' || '''Reference'''
 
|-
 
|-
| [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_FD_STN_MED|FEC.FD.STN.MED]] || Subthalamic Nucleus Medial || modulatory-ach || [http://www.endurance-education.com/endurance-education-com/does-only-our-brainstem-select-our-motor-programs Summary of the organization of the substantia nigra pars reticulata and pedunculopontine nucleus in lamprey (PPN -> STN, abstract)]
+
| [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_FD_STN_MED|FEC.FD.STN.MED]] || Subthalamic Nucleus Medial || modulatory-ach || uncertain || [http://www.endurance-education.com/endurance-education-com/does-only-our-brainstem-select-our-motor-programs Summary of the organization of the substantia nigra pars reticulata and pedunculopontine nucleus in lamprey (PPN -> STN, abstract)]
 
|-
 
|-
|  || [[BrainRegionFEC_FT_SNR_DL|FEC.FT.SNR.DL]] || Substantia Nigra Pars Reticulata Dorsolateral || modulatory-ach || [http://www.endurance-education.com/endurance-education-com/does-only-our-brainstem-select-our-motor-programs Summary of the organization of the substantia nigra pars reticulata and pedunculopontine nucleus in lamprey (PPN -> SNr, abstract)]
+
|  || [[BrainRegionFEC_FT_SNR_DL|FEC.FT.SNR.DL]] || Substantia Nigra Pars Reticulata Dorsolateral || modulatory-ach || uncertain || [http://www.endurance-education.com/endurance-education-com/does-only-our-brainstem-select-our-motor-programs Summary of the organization of the substantia nigra pars reticulata and pedunculopontine nucleus in lamprey (PPN -> SNr, abstract)]
 
|-
 
|-
| [[BrainAreaLRC|LRC]] || [[BrainRegionLRC_MM_SC_INT|LRC.MM.SC.INT]] || Intermediate Superior Colliculus || excitatory-glu || [http://www.sciencedirect.com/science/article/pii/S0387760401003308 Geniculate and Extyrageniculate Paths (PPN -> SC, abstract)]
+
| [[BrainAreaLRC|LRC]] || [[BrainRegionLRC_MM_SC_INT|LRC.MM.SC.INT]] || Intermediate Superior Colliculus || excitatory-glu || uncertain || [http://www.sciencedirect.com/science/article/pii/S0387760401003308 Geniculate and Extyrageniculate Paths (PPN -> SC, abstract)]
 
|-
 
|-
| [[BrainAreaNSA|NSA]] || [[BrainRegionNSA_FD_LGN|NSA.FD.LGN]] || Lateral Geniculate Nucleus || excitatory-glu || [http://www.sciencedirect.com/science/article/pii/S0387760401003308 Geniculate and Extyrageniculate Paths (PPN -> LGN)]
+
| [[BrainAreaNSA|NSA]] || [[BrainRegionNSA_FD_LGN|NSA.FD.LGN]] || Lateral Geniculate Nucleus || excitatory-glu || uncertain || [http://www.sciencedirect.com/science/article/pii/S0387760401003308 Geniculate and Extyrageniculate Paths (PPN -> LGN)]
 
|}
 
|}
  
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* [http://ars.els-cdn.com/content/image/1-s2.0-S0387760401003308-gr2.jpg Geniculate and Extyrageniculate Paths] - see [http://www.sciencedirect.com/science/article/pii/S0387760401003308 Reference]
+
* [http://ars.els-cdn.com/content/image/1-s2.0-S0387760401003308-gr2.jpg Geniculate and Extyrageniculate Paths] - see [http://www.sciencedirect.com/science/article/pii/S0387760401003308 Reference] (CP.GENICULATE-PATHS)
  
<img src="http://ahuman.org/svn/ahwiki/images/ext/e143171723c707d294c39b42fbe01ee6.jpg" alt="unavailable" style="max-width: 100%;">
+
LGN=[[BrainRegionNSA_FD_LGN|Lateral Geniculate Nucleus,NSA.FD.LGN]]
 +
PPN=[[BrainRegionLMC_HT_TG_PPN|Pedunculopontine Tegmental Nuclei,LMC.HT.TG.PPN]]
 +
RF=[[BrainCenterHT_RF|Pontine Reticular Formation,HT.RF]]
 +
Retina=[[BrainRegionLPC_FD_RT|Retinal Nucleus,LPC.FD.RT]]
 +
SC=Superior Colliculus,MM.SC (see [[BrainCenterMM_REF|Reflexes Nuclei of Midbrain Mesencephalon]])
 +
VC=[[BrainCenterNC_LOBE_OCC|Occipital Lobe,NC.LOBE.OCC]]
 +
<img src="http://ahuman.org/svn/ahwiki/images/ext/e143171723c707d294c39b42fbe01ee6.jpg" alt=alt="unavailable" style="max-width: 100%;">
  
* [http://www.endurance-education.com/home/aragorn/www/endurance/htdocs/wp-content/uploads/Stephenson-Jones-2012-Fig-9-1024x489.png Summary of the organization of the substantia nigra pars reticulata and pedunculopontine nucleus in lamprey] - see [http://www.endurance-education.com/endurance-education-com/does-only-our-brainstem-select-our-motor-programs Reference]
+
* [http://www.endurance-education.com/home/aragorn/www/endurance/htdocs/wp-content/uploads/Stephenson-Jones-2012-Fig-9-1024x489.png Summary of the organization of the substantia nigra pars reticulata and pedunculopontine nucleus in lamprey] - see [http://www.endurance-education.com/endurance-education-com/does-only-our-brainstem-select-our-motor-programs Reference] (CM.SN-PPN)
  
<img src="http://ahuman.org/svn/ahwiki/images/ext/ae877872fea7af03677243fd8481c11d.png" alt="unavailable" style="max-width: 100%;">
+
GPe=Globus Pallidus External,FEC.FT.GPE (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 +
GPi=Globus Pallidus Internal,FEC.FT.GPI (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 +
PPN=[[BrainRegionLMC_HT_TG_PPN|Pedunculopontine Tegmental Nuclei,LMC.HT.TG.PPN]]
 +
SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 +
SNr=Substantia Nigra Pars Reticulata,FEC.FT.SNR (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 +
STN=Subthalamic Nucleus,FEC.FD.STN (see [[BrainCenterFEC_FD_STA|Subthalamus Area]])
 +
<img src="http://ahuman.org/svn/ahwiki/images/ext/ae877872fea7af03677243fd8481c11d.png" alt=alt="unavailable" style="max-width: 100%;">
  
* [http://www.impulsecontroldisorders.org/images/6-HippocampalVTA.jpg Combining Novelty, Motivational Salience, and Reward to Control Attention and Learning] - see [http://www.impulsecontroldisorders.org/html/cravings.html Reference]
+
* [http://www.impulsecontroldisorders.org/images/6-HippocampalVTA.jpg Combining Novelty, Motivational Salience, and Reward to Control Attention and Learning] - see [http://www.impulsecontroldisorders.org/html/cravings.html Reference] (CT.LONG-TERM-MEMORY-VTA)
  
<img src="http://www.impulsecontroldisorders.org/images/6-HippocampalVTA.jpg" alt="unavailable" style="max-width: 100%;">
+
ACC=Accumbens Nucleus,FEC.FT.ACC (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 +
CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]])
 +
CA3=Dorsomedial Cornu Ammonis of Hippocampus,FMM.FT.HC.CA3 (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]])
 +
DG=[[BrainRegionFMM_FT_HC_DG|Dentate Gyrus,FMM.FT.HC.DG]]
 +
EC=Entorhinal Cortex,FMM.NC.PH.ET (see [[BrainCenterNC_PHA_RH|Rhinal Cortex]])
 +
PFC=Orbitofrontal Cortex,NC.AL.OPFC (see [[BrainCenterNC_AL_OMPFC|Orbitomedial Prefrontal Cortex]])
 +
PPTG=[[BrainRegionLMC_HT_TG_PPN|Pedunculopontine Tegmental Nuclei,LMC.HT.TG.PPN]]
 +
SUB=Subiculum,FMM.FT.HF.SUB (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]])
 +
VPAL=Ventral Pallidum,FEC.FT.VP (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 +
VTA=[[BrainRegionLMC_MM_VTA|Ventral Tegmental Area,LMC.MM.VTA]]
 +
<img src="http://ahuman.org/svn/ahwiki/images/ext/e3d02da6dc6102c07ec019fae91c8253.jpg" alt=alt="unavailable" style="max-width: 100%;">
  
* [http://www.degruyter.com/view/j/revneuro.2014.25.issue-4/revneuro-2014-0004/graphic/revneuro-2014-0004_fig1.jpg Serotonin regulation of subthalamic neurons] - see [http://www.degruyter.com/view/j/revneuro.2014.25.issue-4/revneuro-2014-0004/revneuro-2014-0004.xml Reference]
+
* [http://www.degruyter.com/view/j/revneuro.2014.25.issue-4/revneuro-2014-0004/graphic/revneuro-2014-0004_fig1.jpg Serotonin regulation of subthalamic neurons] - see [http://www.degruyter.com/view/j/revneuro.2014.25.issue-4/revneuro-2014-0004/revneuro-2014-0004.xml Reference] (CM.SUBTHALAMUS)
  
<img src="http://ahuman.org/svn/ahwiki/images/ext/7c0828e642ed771ff576b3f3a6362c50.jpg" alt="unavailable" style="max-width: 100%;">
+
CTX=Anterior Lobe,NC.LOBE.ANT
 +
GPe=Globus Pallidus External,FEC.FT.GPE (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 +
GPi=Globus Pallidus Internal,FEC.FT.GPI (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 +
PPN=[[BrainRegionLMC_HT_TG_PPN|Pedunculopontine Tegmental Nuclei,LMC.HT.TG.PPN]]
 +
SNr=Substantia Nigra Pars Reticulata,FEC.FT.SNR (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 +
STN=Subthalamic Nucleus,FEC.FD.STN (see [[BrainCenterFEC_FD_STA|Subthalamus Area]])
 +
<img src="http://ahuman.org/svn/ahwiki/images/ext/7c0828e642ed771ff576b3f3a6362c50.jpg" alt=alt="unavailable" style="max-width: 100%;">
  
  

Latest revision as of 18:29, 28 April 2019

Pedunculopontine Tegmental Nuclei

@@Home -> BiologicalLifeResearch -> BrainAreaLMC -> BrainRegionLMC_HT_TG_PPN


This page covers biological details of component Pedunculopontine Tegmental Nuclei. Region is part of aHuman target integrated biological model.

  • Top-down path to region: Hindbrain Metencephalon -> Pontine Tegmental Nuclei (HT.TG) -> Pedunculopontine Tegmental Nuclei (LMC.HT.TG.PPN) (see Mind Maps)
  • Type: nucleus
  • Quality: L0
  • Brain area: Lower Brain - Modulatory Contol Area (LMC)
  • Area circuit: Acetylcholine - PNS Actions and CNS plasticity, arousal and reward (ACH)
  • Role: processor.autonomic
  • Function: Provide sensory feedback to cerebral cortex; modulatory
  • Notes to function:
    • contains Rostral (Pars dissipata, anterior, dissipated subnucleus, GABA), Caudal (Pars compacta, anterior, compact subnucleus, ACh)

(generated)

Components

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Component items:

  • Entopeduncular Nucleus
  • Peripeduncular Nucleus

Connectivity

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LMC.HT.TG.PPN.dot.png

Inbound Region Connections:

Source Area Source Region Source Name Type Role Reference
FEC FEC.FT.VP.VM Ventral Pallidum Ventromedial inhibitory-gaba uncertain Combining Novelty, Motivational Salience, and Reward to Control Attention and Learning (VPAL -> PPTG, abstract)

Outbound Region Connections:

Target Area Target Region Target Name Type Role Reference
FEC FEC.FD.STN.MED Subthalamic Nucleus Medial modulatory-ach uncertain Summary of the organization of the substantia nigra pars reticulata and pedunculopontine nucleus in lamprey (PPN -> STN, abstract)
FEC.FT.SNR.DL Substantia Nigra Pars Reticulata Dorsolateral modulatory-ach uncertain Summary of the organization of the substantia nigra pars reticulata and pedunculopontine nucleus in lamprey (PPN -> SNr, abstract)
LRC LRC.MM.SC.INT Intermediate Superior Colliculus excitatory-glu uncertain Geniculate and Extyrageniculate Paths (PPN -> SC, abstract)
NSA NSA.FD.LGN Lateral Geniculate Nucleus excitatory-glu uncertain Geniculate and Extyrageniculate Paths (PPN -> LGN)

Thirdparty Circuits

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LGN=Lateral Geniculate Nucleus,NSA.FD.LGN
PPN=Pedunculopontine Tegmental Nuclei,LMC.HT.TG.PPN
RF=Pontine Reticular Formation,HT.RF
Retina=Retinal Nucleus,LPC.FD.RT
SC=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon)
VC=Occipital Lobe,NC.LOBE.OCC

GPe=Globus Pallidus External,FEC.FT.GPE (see Basal Ganglia)
GPi=Globus Pallidus Internal,FEC.FT.GPI (see Basal Ganglia)
PPN=Pedunculopontine Tegmental Nuclei,LMC.HT.TG.PPN
SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see Basal Ganglia)
SNr=Substantia Nigra Pars Reticulata,FEC.FT.SNR (see Basal Ganglia)
STN=Subthalamic Nucleus,FEC.FD.STN (see Subthalamus Area)

ACC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia)
CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (see Hippocampal Formation)
CA3=Dorsomedial Cornu Ammonis of Hippocampus,FMM.FT.HC.CA3 (see Hippocampal Formation)
DG=Dentate Gyrus,FMM.FT.HC.DG
EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex)
PFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)
PPTG=Pedunculopontine Tegmental Nuclei,LMC.HT.TG.PPN
SUB=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation)
VPAL=Ventral Pallidum,FEC.FT.VP (see Basal Ganglia)
VTA=Ventral Tegmental Area,LMC.MM.VTA

CTX=Anterior Lobe,NC.LOBE.ANT
GPe=Globus Pallidus External,FEC.FT.GPE (see Basal Ganglia)
GPi=Globus Pallidus Internal,FEC.FT.GPI (see Basal Ganglia)
PPN=Pedunculopontine Tegmental Nuclei,LMC.HT.TG.PPN
SNr=Substantia Nigra Pars Reticulata,FEC.FT.SNR (see Basal Ganglia)
STN=Subthalamic Nucleus,FEC.FD.STN (see Subthalamus Area)


References

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