Pedunculopontine Tegmental Nuclei

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This page covers biological details of component Pedunculopontine Tegmental Nuclei. Region is part of aHuman target integrated biological model.

Top-down path to region: Hindbrain Metencephalon -> Pontine Tegmental Nuclei (HT.TG) -> Pedunculopontine Tegmental Nuclei (LMC.HT.TG.PPN) (see Mind Maps)
Type: nucleus
Brain area: Lower Brain - Modulatory Contol Area
Role: processor.autonomic
Function: Provide sensory feedback to cerebral cortex; modulatory
Notes to function: contains Rostral (Pars dissipata, anterior, dissipated subnucleus, GABA), Caudal (Pars compacta, anterior, compact subnucleus, ACh)

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Components

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Component items:

Connectivity

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LMC.HT.TG.PPN.dot.png

Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
FEC	FEC.FT.VP.VM	Ventral Pallidum Ventromedial	inhibitory-gaba	Combining Novelty, Motivational Salience, and Reward to Control Attention and Learning (VPAL -> PPTG, abstract)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
FEC	FEC.FD.STN.MED	Subthalamic Nucleus Medial	modulatory-ach	Summary of the organization of the substantia nigra pars reticulata and pedunculopontine nucleus in lamprey (PPN -> STN, abstract)
	FEC.FT.SNR.DL	Substantia Nigra Pars Reticulata Dorsolateral	modulatory-ach	Summary of the organization of the substantia nigra pars reticulata and pedunculopontine nucleus in lamprey (PPN -> SNr, abstract)
LRC	LRC.MM.SC.INT	Intermediate Superior Colliculus	excitatory-glu	Geniculate and Extyrageniculate Paths (PPN -> SC, abstract)
NSA	NSA.FD.LGN	Lateral Geniculate Nucleus	excitatory-glu	Geniculate and Extyrageniculate Paths (PPN -> LGN)