BrainRegionLPC SC PH LMG

Lower Marginal Nucleus

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This page covers biological details of component Lower Marginal Nucleus. Region is part of aHuman target integrated biological model.

• Top-down path to region: Spinal Cord -> Posterior/Dorsal Horn (BMA.SC.PH) -> Lamina I (LPC.SC.PH.L1) -> Marginal Nucleus (LPC.SC.PH.MG) -> Lower Marginal Nucleus (LPC.SC.PH.LMG) (see Mind Maps)
• Type: nucleus
• Brain area: Lower Brain - Peripheral Control Area
• Role: sensory.nucleus
• Function: Relay information related to pain and temperature sensation - T7-T12,L1-L5,S1-S5,CX

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Components

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• no child items defined

Connectivity

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Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
LMC	LMC.HL.RP.PL	Raphe Pallidus Nucleus	modulatory-5ht	(unknown reference)
LPC	LPC.PN.SG.LDRG	Lower Dorsal Root Ganglion	excitatory-glu	(unknown reference)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
NCP	NCP.FD.TH.LI	Limitans Nucleus of Thalamus	excitatory-glu	Afferent pain pathways (SC -> Thalamus, abstract)
	NCP.FD.TH.VPI	Ventral Posteroinferior Nucleus	excitatory-glu	Afferent pain pathways (SC -> Thalamus, abstract)
	NCP.FD.TH.VPL	Ventral Posterolateral Nucleus	excitatory-glu	Afferent pain pathways (SC -> Thalamus, abstract)
NDM	NDM.FD.TH.SM	Submedial Nucleus of Thalamus	excitatory-glu	Afferent pain pathways (SC -> Thalamus, abstract)

Thirdparty Circuits

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• Afferent pain pathways - see Reference

References

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• http://www.nature.com/nrn/journal/v14/n7/fig_tab/nrn3516_F2.html