BrainRegionLAC FD HT SUM

Supramammillary Nucleus

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This page covers biological details of component Supramammillary Nucleus. Region is part of aHuman target integrated biological model.

• Top-down path to region: Forebrain Diencephalon -> Hypothalamus (HTA.FD.HT) -> Lateral Hypothalamic Area (HTA.FD.HT.LT) -> Lateral Tuberal Nuclei (HTA.FD.HT.LTUB) -> Supramammillary Nucleus (LAC.FD.HT.SUM) (see Mind Maps)
• Type: nucleus
• Brain area: Lower Brain - Autonomous Control Area
• Role: relay
• Function: control hippocampal plasticity, determine frequency of hippocampal theta rhythm

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Components

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• no child items defined

Connectivity

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Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
FEC	FEC.FT.SNC.MED	Substantia Nigra Pars Compacta Medial	modulatory-da	(unknown reference)
LAC	LAC.FD.HT.PO	Preoptic Nucleus	excitatory-glu	(unknown reference)
LMC	LMC.MM.RF.SUC	Superior Central Raphe Nucleus	modulatory-5ht	(unknown reference)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
FAM	FAM.FT.SEP.DBB	Diagonal Band of Broca	excitatory-glu	[mammillary nucleus and theta rhythm (SupraMM -> SEP, abstract)]
	FAM.FT.SEP.MED	Medial Septal Nucleus	excitatory-glu	[mammillary nucleus and theta rhythm (SupraMM -> SEP, abstract)]
FMM	FMM.FT.HC.CA2	Dorsolateral Cornu Ammonis of Hippocampus	excitatory-glu	[mammillary nucleus and theta rhythm (SupraMM -> HF, abstract)]
	FMM.FT.HC.CA3P	Proximal CA1 of Hippocampus	excitatory-glu	[mammillary nucleus and theta rhythm (SupraMM -> HF, abstract)]
	FMM.FT.HC.DG	Dentate Gyrus	excitatory-glu	[mammillary nucleus and theta rhythm (SupraMM -> HF, abstract)]

Thirdparty Circuits

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• [mammillary nucleus and theta rhythm] - see [[1]]

• [bodies: two memory systems in one] - see [[2]]

References

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• http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F4.html
• http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F2.html