Medial Entorhinal Cortex

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This page covers biological details of component Medial Entorhinal Cortex. Region is part of aHuman target integrated biological model.

Top-down path to region: Cortex -> Parahippocampal Lobe (NC.LOBE.PH) -> Anterior Parahippocampal Gyrus (FMM.NC.PHA) -> Rhinal Cortex (NC.PHA.RH) -> Entorhinal Cortex (FMM.NC.PH.ET) -> Medial Entorhinal Cortex (FMM.NC.PH.MEC) (see Mind Maps)
Type: cortex
Brain area: Forebrain - Memory Management Area
Brodmann ID: 28
Role: processor
Function: Memory consolidation, basic, view inpedepdent position
Notes to function: spatial input to HC; grid cells; path integration computations based on a global frame of reference, primarily using internally generated, self-motion cues and external input about environmental boundaries and scenes; provides hippocampus with coordinate system that underlies spatial context of experience

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Components

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Connectivity

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FMM.NC.PH.MEC.dot.png

|| Source Area || Source Region || Source Name || Type || Reference || || FMM || FMM.FT.HF.SUBD || Distal Subiculum || excitatory-glu || [Network in Hippocampus (SUB -> EC, abstract)] || || || FMM.NC.PH.PAS || Parasubiculum || feedforward-glu || (unknown reference) || || || FMM.NC.PH.POR || Postrhinal Cortex || feedforward-glu || [Cortex Inputs and Outputs (TFTH -> EC, abstract)] || || || FMM.NC.PH.POS || Postsubiculum || feedforward-glu || [Direction Cell Circuit (PSUB -> EC, abstract)] || || || FMM.NC.PH.PRS || Presubiculum || feedforward-glu || [Network in Hippocampus (PRESUB -> EC, abstract)] || || NCP || NCP.NC.MPL.PSCG || Posterior Cingulate Cortex || feedforward-glu || [Spatial Processing Network (PCGRSP -> EnthCortex, abstract)] || || || NCP.NC.MPL.RSC || Retrosplenial Cortex || feedforward-glu || [Spatial Processing Network (PCGRSP -> EnthCortex, abstract)] ||

|| Target Area || Target Region || Target Name || Type || Reference || || FMM || FMM.FD.MB.MMB || Medial Mammillary Nucleus || excitatory-glu || [bodies: two memory systems in one (MedialEC -> MMB, abstract)] || || || FMM.FD.TH.LD || Lateral Dorsal Nucleus of Thalamus || excitatory-glu || [of Diencephalon to Recognition Memory (EC -> LD, abstract)] || || || FMM.FT.HC.CA1P || Proximal CA1 of Hippocampus || excitatory-glu || [projections in the hippocampus (ET -> CA1, abstract)] || || || FMM.FT.HC.CA2 || Dorsolateral Cornu Ammonis of Hippocampus || excitatory-glu || [and its network (EC -> HC, abstract)] || || || FMM.FT.HC.DG || Dentate Gyrus || excitatory-glu || [projections in the hippocampus (ET -> DG, abstract)] ||

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