Revision as of 01:21, 16 June 2015

Dorsal Raphe Nucleus

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This page covers biological details of component Dorsal Raphe Nucleus. Region is part of aHuman target integrated biological model.

• *Top-down path to region*: Midbrain Mesencephalon -> Mesencephalic Reticular Formation (MM.RF) -> Mesencephalic Reticular Formation, Midline Column (MM.RF.MID) -> Dorsal Raphe Nucleus (LMC.MM.RP.DRN) (see Mind Maps)
• *Type*: nucleus
• *Brain area*: Lower Brain - Modulatory Contol Area
• *Role*: relay
• *Function*: Regulation of sleep and mood
• *Notes to function*: Major source of 5HT; inhibitory nucleus

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Components

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• Component items*:
• *Serotonergic cell group B7*

Connectivity

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• Inbound Region Connections:*

|| *Source Area* || *Source Region* || *Source Name* || *Type* || *Reference* || || FAM || BrainRegionFAM_FD_LHB_MED FAM.FD.LHB.MED || Lateral Habenula Medial Part || excitatory-glu || [Habenula Connections (LHb -> DR, abstract)] || || LLC || BrainRegionLLC_FD_TH_SF LLC.FD.TH.SF || Subfascicular Nucleus of Thalamus || inhibitory-gaba || (unknown reference) ||

• Outbound Region Connections:*

|| *Target Area* || *Target Region* || *Target Name* || *Type* || *Reference* || || LPC || BrainRegionLPC_FD_TH_PV LPC.FD.TH.PV || Paraventricular Nucleus of Thalamus || modulatory-5ht || (unknown reference) ||

Thirdparty Circuits

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• [Connections] - see [Reference]

References

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• http://www.scholarpedia.org/article/Habenula