Revision as of 01:18, 16 June 2015

Nucleus Accumbens Core

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This page covers biological details of component Nucleus Accumbens Core. Region is part of aHuman target integrated biological model.

• *Top-down path to region*: Forebrain Telencephalon -> Basal Ganglia (BGA.FT.BG) -> Striatum (BGA.FT.ST) -> Ventral Striatum (BGA.FT.VST) -> Accumbens Nucleus (FEC.FT.ACC) -> Nucleus Accumbens Core (FEC.FT.ACC.CORE) (see Mind Maps)
• *Type*: nucleus
• *Brain area*: Forebrain - Execution Control Area
• *Role*: relay
• *Function*: cognitive processing of motor function related to reward and reinforcement; encodes new motor programs which facilitate acquisition of given reward in future

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Components

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Connectivity

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• Inbound Region Connections:*

|| *Source Area* || *Source Region* || *Source Name* || *Type* || *Reference* || || FAM || BrainRegionFAM_FD_TH_PT FAM.FD.TH.PT || Paratenial Nucleus of Thalamus || excitatory-glu || (unknown reference) || || || FAM.FT.AM.BP || Parvicellular Basal Amygdaloid Nucleus || excitatory-glu || [Amygdala and its network (BLN -> NACC, abstract)] || || FEC || BrainRegionFEC_FD_TH_RH FEC.FD.TH.RH || Rhomboidal Nucleus of Thalamus || excitatory-glu || (unknown reference) || || FMM || BrainRegionFMM_FT_HF_SUBD FMM.FT.HF.SUBD || Distal Subiculum || excitatory-glu || [Nucleus Accumbens (SUB -> NACC, abstract)] || || || FMM.FT.HF.SUBP || Proximal Subiculum || excitatory-glu || [Nucleus Accumbens (SUB -> NACC, abstract)] || || || FMM.NC.PH.LEC || Lateral Entorhinal Cortex || excitatory-glu || [Nucleus Accumbens (EC -> NACC, abstract)] || || || FMM.NC.PH.PAS || Parasubiculum || excitatory-glu || [Nucleus Accumbens (PAS -> NACC, abstract)] || || || FMM.NC.PH.PER || Perirhinal Cortex || excitatory-glu || [Nucleus Accumbens (PRR -> NACC, abstract)] || || LPC || BrainRegionLPC_FD_TH_PV LPC.FD.TH.PV || Paraventricular Nucleus of Thalamus || excitatory-glu || (unknown reference) || || NDM || BrainRegionNDM_NC_AL_FPC NDM.NC.AL.FPC || Lateral Frontopolar Cortex || excitatory-glu || [Affective basal ganglia circuit (OMPFC -> NACC, abstract)] ||

• Outbound Region Connections:*

|| *Target Area* || *Target Region* || *Target Name* || *Type* || *Reference* || || FEC || BrainRegionFEC_FT_SNC_MED FEC.FT.SNC.MED || Substantia Nigra Pars Compacta Medial || inhibitory-gaba || (unknown reference) || || || FEC.FT.VP.DL || Ventral Pallidum Dorsolateral || inhibitory-gaba || [Craving (NACC -> VPAL, abstract)] || || LMC || BrainRegionLMC_MM_VTA LMC.MM.VTA || Ventral Tegmental Area || inhibitory-gaba || [Reward circuit of human brain (NACC -> VTA, abstract)] ||

Thirdparty Circuits

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References

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