CircuitPainAndTemperature

Pain and Temperature Perception

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This page covers components and connections of circuit Pain and Temperature Perception. Circuit is part of aHuman target integrated biological model.

(generated)

Components

(generated)

Mind Area	Component ID	Component Name	Type	Function
PCA	AVA.PN.SG.DRG	Dorsal Root Ganglion	sensory ganglion	Integration of afferent signaling from viscera
AMA	BFA.FT.AM	Amygdala	nucleus	Experiencing and recognizing emotions
ECA	BGA.FT.ACC	Accumbens Nucleus	nucleus	Activate motor functions under attention
	BGA.FT.CN	Caudate Nucleus	nucleus	Excitation of correct action schemas and selection of appropriate sub-goals based on evaluation of action-outcomes
	BGA.FT.PU	Putamen	nucleus	Stimulus-response, or habit, learning
	BGA.FT.VP	Ventral Pallidum	nucleus	Distinguish _wanting_ versus _liking_ enhancements
PCA	BMA.SC.PH.MG	Marginal Nucleus	nucleus	Relay information related to pain and temperature sensation
	BMA.SC.VH.VL	Ventrolateral Nucleus	nucleus	Innervation of limb muscles
EPA	CGA.FD.TH.SM	Submedial Nucleus of Thalamus	nucleus	Pain center
	CGA.NC.DACG	Dorsal Anterior Cingulate Area	cortex, BA 32	Rational Thought Processes
	CGA.NC.SGC	Subgenual Cortex	cortex, BA 25	Influences changes in appetite and sleep
	CGA.NC.VACG	Ventral Anterior Cingulate Area	cortex, BA 24	Seat of Free Will
MCA	FBA.MM.VTA	Ventral Tegmental Area	nucleus	Respond to novel stimuli, unexpected rewards, and reward predictive sensory cues
EPA	FCA.NC.IPG	Inferior Prefrontal Gyrus	cortex, BA 47	Processing of syntax in oral and sign languages
	FCA.NC.LPFC	Dorsolateral Prefrontal Cortex	cortex, BA 09,46	Temporal Integration
	FCA.NC.OMPFC	Orbitomedial Prefrontal Cortex	cortex, BA 10,11,12	Personality
ACA	HMA.HM.TGM.PE5	Peritrigeminal Nucleus	nucleus	Thermoregulation
	HTA.FD.HT.PO	Preoptic Area	nucleus	Thermoregulation
MCA	PHA.FD.TH.LI	Limitans Nucleus of Thalamus	nucleus	Multisensory projection to striatum
MMA	PHA.NC.INS.PIC	Posterior Insular Cortex	cortex, BA 13	Awareness and sensation of pain
	PHA.NC.INS.PPC	Peripaleocortical Claustral	cortex, BA 16	Relays proprioception
	PHA.NC.PH.PIR	Piriform Cortex	cortex, BA 34	Perception of smells

Connections

(generated)

Source Region	Target Region	Type	Reference
AVA.PN.SG.DRG	BMA.SC.PH.MG	ganglion-nucleus	(unknown reference)
BGA.FT.ACC	BGA.FT.VP	nucleus-nucleus	Craving (NACC -> VPAL)
BGA.FT.CN	BGA.FT.PU	nucleus-nucleus	Regulation of Social Brain (Caud -> Put)
BMA.SC.PH.MG	CGA.FD.TH.SM	nucleus-nucleus	(unknown reference)
	PHA.FD.TH.LI	nucleus-nucleus	(unknown reference)
BMA.SC.VH.VL	HMA.HM.TGM.PE5	nucleus-nucleus	(unknown reference)
CGA.FD.TH.SM	CGA.NC.SGC	nucleus-neocortex	Saccadic Vision (Thalamus -> FrontalCortex, abstract)
CGA.NC.SGC	CGA.NC.DACG	neocortex-neocortex	Regulation of Social Brain (SGC -> DACC)
	CGA.NC.VACG	neocortex-neocortex	Regulation of Social Brain (SGC -> VACC)
FBA.MM.VTA	BGA.FT.VP	nucleus-nucleus	Regulation of Social Brain (VTA -> VentPal)
FCA.NC.IPG	CGA.NC.SGC	neocortex-neocortex	Regulation of Social Brain (IFG -> SGC)
FCA.NC.LPFC	BGA.FT.CN	neocortex-nucleus	Regulation of Social Brain (DLPFC -> Caud)
FCA.NC.OMPFC	FCA.NC.IPG	neocortex-neocortex	Regulation of Social Brain (OFC -> IFG)
HMA.HM.TGM.PE5	HTA.FD.HT.PO	nucleus-nucleus	(unknown reference)
PHA.FD.TH.LI	CGA.NC.DACG	nucleus-neocortex	Saccadic Vision (Thalamus -> FrontalCortex, abstract)
	PHA.NC.INS.PPC	nucleus-neocortex	Amygdalar disruption of prefrontal cortex (TH -> INS, abstract)
PHA.NC.INS.PIC	PHA.NC.INS.PPC	neocortex-neocortex	Gustatory sensory system of rat and macaque (Iav -> IadIap, abstract)
PHA.NC.INS.PPC	BFA.FT.AM	neocortex-nucleus	(unknown reference)
	CGA.NC.DACG	neocortex-neocortex	Amygdalar disruption of prefrontal cortex (INS -> ACG, abstract)
	FCA.NC.OMPFC	neocortex-neocortex	Amygdalar disruption of prefrontal cortex (INS -> MPFC, abstract)
	PHA.NC.PH.PIR	neocortex-neocortex	(unknown reference)