CircuitConsciousMotivations

High-Level Motivations

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This page covers components and connections of circuit High-Level Motivations. Circuit is part of aHuman target integrated biological model.

(generated)

Components

(generated)

Mind Area	Component ID	Component Name	Type	Function
AMA	BFA.FT.AM	Amygdala	nucleus	Experiencing and recognizing emotions
	BFA.FT.BNST	Bed Nucleus of Stria Terminalis	nucleus	Mediate slow longer-lasting responses that accompany sustained threats
	BFA.FT.SEP	Septal Nucleus	nucleus	Inhibition of fear and expression of pleasurable responses
ECA	BGA.FT.ACC	Accumbens Nucleus	nucleus	Activate motor functions under attention
	BGA.FT.SN.PR	Substantia Nigra Pars Reticulata	nucleus	Convey final processed signals of basal ganglia to thalamus and superior colliculus
MCA	BMA.HP.PB	Parabrachial Nucleus	nucleus	Source of short-latency nociceptive input
EPA	CGA.FD.TH.LD	Lateral Dorsal Nucleus of Thalamus	nucleus	Head direction, spatial learning
	CGA.NC.DACG	Dorsal Anterior Cingulate Area	cortex, BA 32	Rational Thought Processes
	CGA.NC.MPL.PCG	Posterior Cingulate Cortex	cortex, BA 23,31	Self-awareness, pain and episodic memory retrieval
	CGA.NC.MPL.RSC	Retrosplenial Cortex	cortex, BA 26,29,30	Processing of emotionally salient stimuli
	CGA.NC.PACG	Pregenual Area	cortex, BA 33	Sensation of Emotion
	CGA.NC.SGC	Subgenual Cortex	cortex, BA 25	Influences changes in appetite and sleep
	CGA.NC.SPL.PF	Rostral Precuneus	cortex, BA 07	Spatial orientation, representation of the self
	CGA.NC.VACG	Ventral Anterior Cingulate Area	cortex, BA 24	Seat of Free Will
MCA	FBA.MM.PAG	Periaqueductal Gray Matter	nucleus	Descending modulation of pain and in defensive behaviour
	FBA.MM.VTA	Ventral Tegmental Area	nucleus	Respond to novel stimuli, unexpected rewards, and reward predictive sensory cues
EPA	FCA.FD.TH.MD	Mediodorsal Nucleus of Thalamus	nucleus	Attention, planning, organization, abstract thinking, multi-tasking, and active memory
	FCA.NC.LPFC	Dorsolateral Prefrontal Cortex	cortex, BA 09,46	Temporal Integration
	FCA.NC.OMPFC	Orbitomedial Prefrontal Cortex	cortex, BA 10,11,12	Personality
ACA	HTA.FD.HT.AH	Anterior Hypothalamic Nucleus	nucleus	Thermoregulation, panting, sweating
	HTA.FD.HT.RCH	Retrochiasmatic Area	nucleus	Maintenance of normal hypothalamic-pituitary-adrenal function
BAA	SMA.NC.SPL.SA	Somatosensory Association Cortex	cortex, BA 05	Locating objects in space

Connections

(generated)

Source Region	Target Region	Type	Reference
BFA.FT.AM	CGA.NC.PACG	nucleus-neocortex	Amygdalar disruption of prefrontal cortex (AM -> ACG, abstract)
	CGA.NC.VACG	nucleus-neocortex	Directed Effort Network (AM -> vACC)
	FCA.FD.TH.MD	nucleus-nucleus	Prefrontal Cortex (PFC) in emotional behavior (AM -> TH)
	FCA.NC.OMPFC	nucleus-neocortex	Amygdalar disruption of prefrontal cortex (AM -> MPFC)
BFA.FT.SEP	CGA.NC.SGC	nucleus-neocortex	(unknown reference)
CGA.FD.TH.LD	CGA.NC.SPL.PF	nucleus-neocortex	(unknown reference)
CGA.NC.DACG	CGA.NC.VACG	neocortex-neocortex	Principal Connections of Hippocampus (DorsalCingulate -> VentralCingulate)
CGA.NC.MPL.RSC	FCA.NC.LPFC	neocortex-neocortex	Prefrontal Cortex (PFC) in emotional behavior (PCA -> LPFC, abstract)
	FCA.NC.OMPFC	neocortex-neocortex	Prefrontal Cortex (PFC) in emotional behavior (PCA -> OPFC, abstract)
CGA.NC.SGC	BFA.FT.BNST	neocortex-nucleus	(unknown reference)
	BMA.HP.PB	neocortex-nucleus	(unknown reference)
	FBA.MM.PAG	neocortex-nucleus	(unknown reference)
	HTA.FD.HT.AH	neocortex-nucleus	(unknown reference)
CGA.NC.SPL.PF	CGA.FD.TH.LD	neocortex-nucleus	Thalamocortical relationships (sLD -> LD, abstract)
	CGA.NC.MPL.RSC	neocortex-neocortex	(unknown reference)
	CGA.NC.PACG	neocortex-neocortex	Global visual system (ParietalCortex -> FrontalCortex, abstract)
CGA.NC.VACG	CGA.NC.MPL.PCG	neocortex-neocortex	Principal Connections of Hippocampus (VentralCingulate -> PosteriorCingulate)
FCA.FD.TH.MD	CGA.NC.PACG	nucleus-neocortex	Saccadic Vision (Thalamus -> FrontalCortex, abstract)
FCA.NC.OMPFC	BGA.FT.ACC	neocortex-nucleus	Affective basal ganglia circuit (OMPFC -> NACC)
	BGA.FT.SN.PR	neocortex-nucleus	Craving (OMPFC -> SNr)
	CGA.NC.PACG	neocortex-neocortex	Role for serotonin in moral behavior (OMPFC -> ACG, abstract)
	CGA.NC.VACG	neocortex-neocortex	Directed Effort Network (OPFC -> vACC)
	FBA.MM.VTA	neocortex-nucleus	Craving (OMPFC -> VTA)
	FCA.NC.LPFC	neocortex-neocortex	Prefrontal Cortex (PFC) in emotional behavior (OPFC -> LPFC)
	HTA.FD.HT.RCH	neocortex-nucleus	Prefrontal Cortex (PFC) in emotional behavior (OPFC -> HT, abstract)
SMA.NC.SPL.SA	FCA.NC.OMPFC	neocortex-neocortex	Cortico-Cortical Connectivity (SA -> PFC, abstract)