CircuitMuscleControl

Muscle Control

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This page covers components and connections of circuit Muscle Control. Circuit is part of aHuman target integrated biological model.

(generated)

Components

(generated)

Mind Area	Component ID	Component Name	Type	Function
ACA	AVA.HM.VG	Vagus Nucleus	nucleus	Parasympathetic vagal functions in the gastrointestinal tract, lungs
	AVA.PN.PSYM.ILG	Intralaryngeal Peripheral Ganglion	parasympathetic ganglion	parasympathetic motor of larynx, c.n. X
	AVA.PN.PSYM.PPG	Pelvic Peripheral Ganglion	parasympathetic ganglion	Sigmoid, rectum, bladder, and external genitalia
	AVA.PN.SYM.ARG	Aorticorenal Ganglion	sympathetic ganglion	Kidney, Ureter
	AVA.PN.SYM.CEG	Coelic Ganglion	sympathetic ganglion	Liver, stomach, pancreas, small intestine
	AVA.PN.SYM.IMG	Inferior Mesenteric Ganglion	sympathetic ganglion	Bladder, rectum, reproductive organs
	AVA.PN.SYM.MCG	Middle Cervical Ganglion	sympathetic ganglion	Eye, tear and salivatory glands
	AVA.PN.SYM.SCG	Superior Cervical Ganglion	sympathetic ganglion	Eye, tear and salivatory glands
	AVA.PN.SYM.SMG	Superior Mesenteric Ganglion	sympathetic ganglion	Large intestine, rectum
	AVA.SC.IZ.IML	Intermediolateral Nucleus	nucleus	Mediate entire sympathetic innervation of body
	AVA.SC.VH.ONF	Onuf's Nucleus	nucleus	Maintenance of urination and defecation, muscular contraction during orgasm
AMA	BFA.FT.NBM	Basal Nucleus of Meynert	nucleus	Control imagination vs perception
ECA	BGA.FT.GPI	Globus Pallidus Internal	nucleus	Output nuclei of basal ganglia to neocortex
	BGA.FT.PU	Putamen	nucleus	Stimulus-response, or habit, learning
	BGA.FT.SN.PC	Substantia Nigra Pars Compacta	nucleus	Fine motor control, temporal processing
MCA	BMA.HP.PB	Parabrachial Nucleus	nucleus	Source of short-latency nociceptive input
	FBA.HP.LC	Locus Coeruleus	nucleus	Regulate the intensity of responses to salient stimuli
	FBA.MM.PAG	Periaqueductal Gray Matter	nucleus	Descending modulation of pain and in defensive behaviour
	FBA.MM.VTA	Ventral Tegmental Area	nucleus	Respond to novel stimuli, unexpected rewards, and reward predictive sensory cues
EPA	FCA.NC.LPFC	Dorsolateral Prefrontal Cortex	cortex, BA 09,46	Temporal Integration
	FCA.NC.OMPFC	Orbitomedial Prefrontal Cortex	cortex, BA 10,11,12	Personality
PCA	HMA.HP.PTP.PTR	Principal Trigeminal Nucleus	nucleus	Facial Somatic Sensations
	HMA.MM.MSTR	Mesencephalic Trigeminal Nucleus	sensory ganglion	unconscious proprioception from muscle spindles; facial somatic sensations from muscles of mastication, monosynaptic masticatory reflex
ACA	HTA.FD.HT.PO	Preoptic Area	nucleus	Thermoregulation
	HTA.FD.HT.PV	Paraventricular Nucleus	nucleus	Regulate appetite and autonomic functions
	MBA.HP.BR	Barrington's Nucleus	nucleus	Supraspinal regulation of urination
LCA	MBA.HP.CR	Cerebellum	nucleus	Motor coordination
	MBA.HP.PN.PBB	Pontobulbar Body	nucleus	Control voluntary muscle activities
MAA	MCA.FD.TH.VA	Ventral Anterior Nucleus	nucleus	Relay BGA.SN, BGA.GPI, FCA.OMPFC, FCA.CG to MCA.PMC, MCA.SMC
	MCA.FD.TH.VL	Ventral Lateral Nucleus	nucleus	Relay BSA.CR to MCA.MC
	MCA.NC.MC	Motor Cortex	cortex, BA 04	Execution of required voluntary movements
	MCA.NC.PMC.F4	Ventral Caudal Premotor Cortex	cortex, BA 06	Sensory guidance of movement
	MCA.NC.PMC.F5	Ventral Rostral Premotor Cortex	cortex, BA 06	Shaping hand during grasping
	MCA.NC.SMC	Supplementary Motor Cortex	cortex, BA 06	Process sequences of movements and coordinate bilateral movements
MMA	PHA.NC.PH.PRR	Perirhinal Cortex	cortex, BA 35	Associate different visual views of objects and their various nonvisual attributes
BAA	SMA.FD.TH.VPL	Ventral Posterolateral Nucleus	nucleus	Relays somatic information from body to S1
	SMA.NC.PG.S1	Somatosensory Cortex	cortex, BA 01,02,03	Muscle and skin receptors
SAA	VCA.NC.IPS.AIP	Anterior Intraparietal Sulcus	cortex, BA 39	Represent shape, size, and orientation of objects to be grasped
	VCA.NC.IPS.VIP	Ventral Intraparietal Sulcus	cortex, BA 39	Merge visual, somatosensory, auditory, and vestibular senses
	VCA.NC.IT.TE	Inferotemporal Cortex	cortex, BA 20	Represent different views of objects

Connections

(generated)

Source Region	Target Region	Type	Reference
AVA.HM.VG	AVA.PN.PSYM.ILG	nucleus-ganglion	(unknown reference)
AVA.PN.SYM.IMG	FBA.MM.PAG	ganglion-nucleus	[overview of spinobulbospinal micturition reflex pathway (IMG -> PAG)]
	MBA.HP.BR	ganglion-nucleus	[overview of spinobulbospinal micturition reflex pathway (IMG -> BAR)]
AVA.SC.IZ.IML	AVA.PN.PSYM.PPG	nucleus-ganglion	[overview of spinobulbospinal micturition reflex pathway (IML -> PEL)]
	AVA.PN.SYM.ARG	nucleus-ganglion	(unknown reference)
	AVA.PN.SYM.CEG	nucleus-ganglion	(unknown reference)
	AVA.PN.SYM.MCG	nucleus-ganglion	(unknown reference)
	AVA.PN.SYM.SCG	nucleus-ganglion	(unknown reference)
	AVA.PN.SYM.SMG	nucleus-ganglion	(unknown reference)
	AVA.SC.VH.ONF	nucleus-nucleus	[overview of spinobulbospinal micturition reflex pathway (IML -> ONF)]
BFA.FT.NBM	FCA.NC.OMPFC	nucleus-neocortex	[and pathophysiology of lower urinary tract (NBM -> MPFC)]
BGA.FT.GPI	MCA.FD.TH.VL	nucleus-nucleus	[Ganglia Activity (GPi -> VLo)]
BGA.FT.PU	FBA.HP.LC	nucleus-nucleus	[and pathophysiology of lower urinary tract (PU -> LC)]
BGA.FT.SN.PC	MBA.HP.CR	nucleus-nucleus	[Cortex (PFC) in motor behavior (SN -> CR, abstract)]
BMA.HP.PB	AVA.HM.VG	nucleus-nucleus	[and pathophysiology of lower urinary tract (PBN -> DVM)]
FBA.HP.LC	AVA.SC.IZ.IML	nucleus-nucleus	[and pathophysiology of lower urinary tract (LC -> IML)]
FBA.MM.PAG	MBA.HP.BR	nucleus-nucleus	[overview of spinobulbospinal micturition reflex pathway (PAG -> BAR)]
FBA.MM.VTA	HTA.FD.HT.PO	nucleus-nucleus	[and pathophysiology of lower urinary tract (VTA -> MPOA)]
	HTA.FD.HT.PV	nucleus-nucleus	[and pathophysiology of lower urinary tract (VTA -> PVN)]
FCA.NC.LPFC	MCA.FD.TH.VA	neocortex-nucleus	[Cortex (PFC) in motor behavior (LPFC -> TH, abstract)]
HMA.MM.MSTR	HMA.HP.PTP.PTR	ganglion-nucleus	(unknown reference)
MBA.HP.BR	AVA.SC.IZ.IML	nucleus-nucleus	[overview of spinobulbospinal micturition reflex pathway (BAR -> IML)]
MBA.HP.CR	FCA.NC.LPFC	nucleus-neocortex	[Cortex (PFC) in motor behavior (CR -> LPFC)]
	MCA.FD.TH.VL	nucleus-nucleus	[relationships (s1VL -> VL)]
MBA.HP.PN.PBB	MBA.HP.CR	nucleus-nucleus	[Cortex (PFC) in motor behavior (PN -> CR, abstract)]
MCA.FD.TH.VL	MCA.NC.MC	nucleus-neocortex	[relationships (VL -> pVL)]
MCA.NC.MC	MBA.HP.PN.PBB	neocortex-nucleus	[Cortex (PFC) in motor behavior (MC -> PN, abstract)]
	SMA.NC.PG.S1	neocortex-neocortex	[visual system (FrontalCortex -> ParietalCortex, abstract)]
MCA.NC.PMC.F4	FCA.NC.LPFC	neocortex-neocortex	[Connectivity (MA -> PFC, abstract)]
MCA.NC.PMC.F5	SMA.NC.PG.S1	neocortex-neocortex	[Control of Grasping (F5 -> S2)]
	VCA.NC.IPS.AIP	neocortex-neocortex	[Control of Grasping (F5 -> AIP)]
SMA.FD.TH.VPL	SMA.NC.PG.S1	nucleus-neocortex	[matrix (TH.VPL -> S1)]
SMA.NC.PG.S1	MCA.NC.PMC.F5	neocortex-neocortex	[Control of Grasping (S2 -> F5)]
	MCA.NC.SMC	neocortex-neocortex	[visual system (ParietalCortex -> FrontalCortex, abstract)]
	PHA.NC.PH.PRR	neocortex-neocortex	(unknown reference)
VCA.NC.IPS.AIP	MCA.NC.PMC.F4	neocortex-neocortex	[Control of Grasping (AIP -> F4)]
	MCA.NC.PMC.F5	neocortex-neocortex	[Control of Grasping (AIP -> F5)]
VCA.NC.IPS.VIP	MCA.NC.PMC.F4	neocortex-neocortex	[Control of Grasping (VIP -> F4)]
VCA.NC.IT.TE	VCA.NC.IPS.AIP	neocortex-neocortex	[Control of Grasping (IT -> AIP, abstract)]