BrainRegionNMA NC SMC F6

Pre-Supplementary Motor Area

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This page covers biological details of component Pre-Supplementary Motor Area. Region is part of aHuman target integrated biological model.

• Top-down path to region: Cerebral Cortex -> Anterior Lobe (NC.LOBE.ANT) -> Supplementary Motor Cortex (NMA.NC.SMC) -> Pre-Supplementary Motor Area (NMA.NC.SMC.F6) (see Mind Maps)
• Type: cortex
• Brain area: Neocortical Brain - Motor Aggregation Area
• Brodmann ID: 06
• Role: processor
• Function: High level motor functions; Numerical and verbal mental-operation tasks
• Notes to function: from TH/VLpc, MD from caudate, CR; F5/24c/46; no connections with F1

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Components

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• no child items defined

Connectivity

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Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
NDM	NDM.NC.AL.DLPFCR	Rostral Mid-Dorsolateral Prefrontal Cortex	feedforward-glu	Primate Control of Grasping (46 -> F6, abstract)
NMA	NMA.FD.TH.VA	Ventral Anterior Nucleus	excitatory-glu	Primate Control of Grasping (BTH -> F6)
	NMA.FD.TH.VL	Ventral Lateral Nucleus	excitatory-glu	Basal Ganglia Activity (VLo -> SMC, abstract)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
FEC	FEC.FD.STN.MED	Subthalamic Nucleus Medial	excitatory-glu	(unknown reference)
	FEC.FT.PU.MED	Dorsal Putamen Medial	excitatory-glu	Primate Control of Grasping (F6 -> BG, abstract)
NMA	NMA.NC.PMC.F4	Ventral Caudal Premotor Cortex	feedforward-glu	Primate Control of Grasping (F6 -> F4)
	NMA.NC.PMC.F5	Ventral Rostral Premotor Cortex	feedforward-glu	Primate Control of Grasping (F6 -> F5)

Thirdparty Circuits

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• Primate Control of Grasping - see Reference

References

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• http://www.sciencedirect.com/science/article/pii/S0893608098000471