View source for BrainRegionNPE NC SMC SEF

<pre style="color: green">Supplementary Eye Field</pre>
@@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainAreaNPE]] -> [[BrainRegionNPE_NC_SMC_SEF]]
----

This page covers biological details of component Supplementary Eye Field.
Region is part of aHuman target integrated biological model.

* '''Top-down path to region''': Cerebral Cortex -> Anterior Lobe (NC.LOBE.ANT) -> [[BrainCenterNMA_NC_SMC|Supplementary Motor Cortex]] (NMA.NC.SMC) -> [[BrainRegionNPE_NC_SMC_SEF|Supplementary Eye Field]] (NPE.NC.SMC.SEF) (see [[OverallMindMaps|Mind Maps]])
* '''Type''': cortex
* '''Quality''': L0
* '''Brain area''': [[BrainAreaNPE|Neocortical Brain - Unimodal Execution Area]] (NPE)
* '''Area circuit''': Cortical Vision Control (CVC)
* '''Brodmann ID''': 06
* '''Role''': cortex.generic
* '''Function''': high level aspects of saccade control
* '''Notes to function''': 
** Complex spatial transformations, learned transformations, and executive cognitive functions
**  dorsorostral of F7
(generated)
= Components =
(generated)


* no child items defined

= Connectivity =
(generated)


http://ahuman.org/svn/ahwiki/images/dot/NPE.NC.SMC.SEF.dot.png

'''Inbound Region Connections:'''

{| class=wikitable width=80%
| '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Role''' || '''Reference'''
|-
| [[BrainAreaNDM|NDM]] || [[BrainRegionNDM_NC_AL_DLPFCR|NDM.NC.AL.DLPFCR]] || Rostral Mid-Dorsolateral Prefrontal Cortex || feedforward-glu || uncertain ||[http://ahuman.org/svn/ahengine/research/articles/Biological/2008-dorsal-stream.pdf 3 Visual Cortex Paths (LPC -> pre-SMA, abstract)]
|-
| [[BrainAreaNPE|NPE]] || [[BrainRegionNPE_NC_SPL_PG|NPE.NC.SPL.PG]] || Caudal Precuneus || feedforward-glu || uncertain ||[http://thebrainlabs.com/brain.shtml Movement Planning (PPC -> SMC, abstract)]
|}

'''Outbound Region Connections:'''

{| class=wikitable width=80%
| '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Role''' || '''Reference'''
|-
| [[BrainAreaLRC|LRC]] || [[BrainRegionLRC_MM_RP_RIP|LRC.MM.RP.RIP]] || Raphe Interpositus Nucleus || excitatory-glu || uncertain || [http://www.sciencedirect.com/science/article/pii/S0006899301025987 Horizontal saccades and smooth pursuit movements (FEFSEF -> RIP, abstract)]
|-
| [[BrainAreaNPE|NPE]] || [[BrainRegionNPE_NC_PMC_AFEF|NPE.NC.PMC.AFEF]] || Anterior Frontal Eye Field || feedforward-glu || uncertain || [http://www.cixip.com/index.php/page/content/id/1190 Summary of eye movement control (SEF -> FEF, abstract)]
|}

= Thirdparty Circuits =
(generated)

* [http://ars.els-cdn.com/content/image/1-s2.0-S0006899301025987-gr1.gif Horizontal saccades and smooth pursuit movements] - see [http://www.sciencedirect.com/science/article/pii/S0006899301025987 Reference] (CP.VISION-SACCADES)

 Bechterew=[[BrainRegionLLC_HT_PRF_RTMG|Pontine Reticulotegmental Nucleus,LLC.HT.PRF.RTMG]]
 CR=Cerebellum,LLC.HT.CR (see [[BrainCenterLLC_HT_CRC|Cerebellar Complex]])
 FEFSEF=Anterior Lobe,NC.LOBE.ANT
 LGB=[[BrainRegionNSA_FD_LGN|Lateral Geniculate Nucleus,NSA.FD.LGN]]
 PPRF=Paramedian Pontine Reticular Formation,HT.PRF.PPRF (see [[BrainCenterHT_RF|Pontine Reticular Formation]])
 PrimaryVisual=[[BrainRegionNSA_NC_OCC_V1|Primary Visual Cortex,NSA.NC.OCC.V1]]
 RIP=[[BrainRegionLRC_MM_RP_RIP|Raphe Interpositus Nucleus,LRC.MM.RP.RIP]]
 SC=Superior Colliculus,MM.SC (see [[BrainCenterMM_REF|Reflexes Nuclei of Midbrain Mesencephalon]])
 Striatum=Striatum,FEC.FT.ST (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 Vestibular=[[BrainRegionLPC_HT_SVBN|Superior Vestibular Nucleus,LPC.HT.SVBN]]
 VisualAssociation=[[BrainRegionNPE_NC_SPL_PG|Caudal Precuneus,NPE.NC.SPL.PG]]
<img src="http://ahuman.org/svn/ahwiki/images/ext/589bb18de54efec1ca32303d0caa76ff.gif" alt=alt="unavailable" style="max-width: 100%;">

* [http://ars.els-cdn.com/content/image/1-s2.0-S0959438808001566-gr1.jpg Global visual system] - see [http://www.sciencedirect.com/science/article/pii/S0959438808001566 Reference] (CP.GLOBAL-VISUAL-SYSTEM)

 ATH=Anterior Nucleus of Thalamus,FD.TH.AN (see [[BrainCenterFD_TH_CR|Cognitive Thalamus]])
 BGA=[[BrainCenterFEC_FT_BG|Basal Ganglia,FEC.FT.BG]]
 FrontalCortex=Anterior Lobe,NC.LOBE.ANT
 LGN=[[BrainRegionNSA_FD_LGN|Lateral Geniculate Nucleus,NSA.FD.LGN]]
 OPN=[[BrainRegionLPC_MM_OCN|Oculomotor Nucleus,LPC.MM.OCN]]
 ParietalCortex=Parietal Lobe,NC.LOBE.PAR
 Pulvinar=Pulvinar,FD.PV (see [[BrainCenterFD_TH_SR|Sensory Thalamus]])
 RF=[[BrainCenterHT_RF|Pontine Reticular Formation,HT.RF]]
 Retina=[[BrainRegionLPC_FD_RT|Retinal Nucleus,LPC.FD.RT]]
 SCi=Superior Colliculus,MM.SC (see [[BrainCenterMM_REF|Reflexes Nuclei of Midbrain Mesencephalon]])
 SCs=Superior Colliculus,MM.SC (see [[BrainCenterMM_REF|Reflexes Nuclei of Midbrain Mesencephalon]])
 SNc=[[BrainRegionFEC_FT_SNC_LT|Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT]]
 SNr=[[BrainRegionFEC_FT_SNR_DL|Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL]]
 SpinalCord=Lamina IX,SC.VH.L9 (see [[BrainCenterSC_VH|Anterior/Ventral Horn]])
 Striatum=Striatum,FEC.FT.ST (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 VisualCortex=[[BrainCenterNC_LOBE_OCC|Occipital Lobe,NC.LOBE.OCC]]
<img src="http://ahuman.org/svn/ahwiki/images/ext/7192d7e1c7041f25a6eddc32c4f67e91.jpg" alt=alt="unavailable" style="max-width: 100%;">

* [http://www.cixip.com/Public/kindeditor/attached/image/20121030/20121030134649_52795.jpg Summary of eye movement control] - see [http://www.cixip.com/index.php/page/content/id/1190 Reference] (CP.EYE-FIELDS)

 DLPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see [[BrainCenterNC_AL_LPFC|Lateral Prefrontal Cortex]])
 FEF=Frontal Eye Field,NMA.NC.PMC.FEF (see [[BrainCenterNC_PMC|Premotor Cortex]])
 PEF=Posterior Eye Field,NPE.NC.IPS.PEF (see [[BrainCenterNSA_NC_IPS|Intraparietal Sulcus]])
 PPRF=Paramedian Pontine Reticular Formation,HT.PRF.PPRF (see [[BrainCenterHT_RF|Pontine Reticular Formation]])
 SC=Superior Colliculus,MM.SC (see [[BrainCenterMM_REF|Reflexes Nuclei of Midbrain Mesencephalon]])
 SEF=[[BrainRegionNPE_NC_SMC_SEF|Supplementary Eye Field,NPE.NC.SMC.SEF]]
 riMLF=[[BrainRegionLRC_MM_CJ|Cajal Nucleus,LRC.MM.CJ]]
<img src="http://ahuman.org/svn/ahwiki/images/ext/1e34c15be19f98dbf300ca306c8f4c53.jpg" alt=alt="unavailable" style="max-width: 100%;">

* [http://img.springerimages.com/Images/Springer/PUB=Springer-Verlag-Berlin-Heidelberg/JOU=00359/VOL=2005.191/ISU=3/ART=2004_565/MediaObjects/WATER_s00359-004-0565-9fhc1.jpg Oculomotor decision-making] - see [http://www.springerimages.com/Images/LifeSciences/1-10.1007_s00359-004-0565-9-0 Reference] (CP.OCULOMOTOR-DECISION-MAKING)

 AMYG=[[BrainCenterFAM_FT_AM|Amygdala,FAM.FT.AM]]
 CGa=Anterior Cingulate Cortex,NC.AL.ACG (see [[BrainCenterNC_ACG|Anterior Cingulate Area]])
 CGp=[[BrainRegionNCP_NC_MPL_PSCG|Posterior Cingulate Cortex,NCP.NC.MPL.PSCG]]
 Caudate=Caudate Nucleus,FEC.FT.CN (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 FEF=Frontal Eye Field,NMA.NC.PMC.FEF (see [[BrainCenterNC_PMC|Premotor Cortex]])
 LIP=[[BrainRegionNPE_NC_IPS_LIP|Lateral Intraparietal Sulcus,NPE.NC.IPS.LIP]]
 NAC=Accumbens Nucleus,FEC.FT.ACC (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 OFC=Orbitofrontal Cortex,NC.AL.OPFC (see [[BrainCenterNC_AL_OMPFC|Orbitomedial Prefrontal Cortex]])
 PFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see [[BrainCenterNC_AL_LPFC|Lateral Prefrontal Cortex]])
 SC=Superior Colliculus,MM.SC (see [[BrainCenterMM_REF|Reflexes Nuclei of Midbrain Mesencephalon]])
 SEF=[[BrainRegionNPE_NC_SMC_SEF|Supplementary Eye Field,NPE.NC.SMC.SEF]]
 SNc=[[BrainRegionFEC_FT_SNC_LT|Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT]]
 SNr=[[BrainRegionFEC_FT_SNR_DL|Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL]]
 Thalamus=Thalamus,FD.TH
 VTA=[[BrainRegionLMC_MM_VTA|Ventral Tegmental Area,LMC.MM.VTA]]
<img src="http://ahuman.org/svn/ahwiki/images/ext/1d4f1e638e95cbcc831ce811b7c2518a.jpg" alt=alt="unavailable" style="max-width: 100%;">


= References =
(generated)

* http://www.sciencedirect.com/science/article/pii/S0006899301025987
* http://www.sciencedirect.com/science/article/pii/S0959438808001566
* http://www.cixip.com/index.php/page/content/id/1190
* http://www.springerimages.com/Images/LifeSciences/1-10.1007_s00359-004-0565-9-0