View source for BrainRegionLAC FD HT LTN


<pre style="color: green">Lateral Hypothalamic Nucleus</pre>
@@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainAreaLAC]] -> [[BrainRegionLAC_FD_HT_LTN]]
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This page covers biological details of component Lateral Hypothalamic Nucleus.
Region is part of aHuman target integrated biological model.

* '''Top-down path to region''': Forebrain Diencephalon -> [[BrainCenterFD_HT|Hypothalamus]] (FD.HT) -> Lateral Hypothalamic Area (LAC.FD.HT.LT) -> [[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus]] (LAC.FD.HT.LTN) (see [[OverallMindMaps|Mind Maps]])
* '''Type''': nucleus
* '''Brain area''': [[BrainAreaLAC|Lower Brain - Autonomous Control Area]]
* '''Role''': relay
* '''Function''': feeding center
* '''Notes to function''': lesions - lack of appetite
(generated)
= Components =
(generated)


* no child items defined

= Connectivity =
(generated)


http://ahuman.org/svn/ahwiki/images/dot/LAC.FD.HT.LTN.dot.png

'''Inbound Region Connections:'''

{| class=wikitable width=80%
| '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Reference'''
|-
| [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FT_AM_BP|FAM.FT.AM.BP]] || Parvicellular Basal Amygdaloid Nucleus || excitatory-glu || [http://www.surgicalneurologyint.com/article.asp?issn=2152-7806;year=2012;volume=3;issue=2;spage=40;epage=46;aulast=Langevin Amygdala and its network (BLN -> HTS)]
|-
|  || [[BrainRegionFAM_FT_AM_CEM|FAM.FT.AM.CEM]] || Medial Central Amygdaloid Nucleus || excitatory-glu || [http://neuropolitics.org/defaultmay10.asp Amygdalar disruption of prefrontal cortex (AM -> HT.L, abstract)]
|-
|  || [[BrainRegionFAM_FT_SEP_SH|FAM.FT.SEP.SH]] || Septohippocampal Nucleus || excitatory-glu || [http://www.thebrainlabs.com Cingulate Gyrus (SEP -> HT, abstract)]
|-
| [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_FT_ACC_SH|FEC.FT.ACC.SH]] || Nucleus Accumbens Shell || inhibitory-gaba || (unknown reference)
|-
| [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_AR|LAC.FD.HT.AR]] || Arcuate Nucleus of Hypothalamus || excitatory-glu || [http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf Intrahypothalamic connections important for neural control of food intake and energy balance (ARC -> LHA)]
|-
|  || [[BrainRegionLAC_FD_HT_DM|LAC.FD.HT.DM]] || Dorsomedial Hypothalamic Nucleus || excitatory-glu || [http://www.dana.org/Publications/ReportDetails.aspx?id=44217 Eating and sleeping to survive (DMH -> LHA)]
|-
|  || [[BrainRegionLAC_FD_HT_VM|LAC.FD.HT.VM]] || Ventromedial Hypothalamic Nucleus || excitatory-glu || [http://ajpregu.physiology.org/content/302/2/R215 Glucose-sensing neural network (VMH -> LHA)]
|-
| [[BrainAreaLPC|LPC]] || [[BrainRegionLPC_HL_SOL|LPC.HL.SOL]] || Solitary Nucleus || excitatory-glu || [http://neuroscience.uth.tmc.edu/s4/chapter04.html Schematic of hypothalamic circuitry underlying satiety (NTS -> LHA)]
|}

'''Outbound Region Connections:'''

{| class=wikitable width=80%
| '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Reference'''
|-
| [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FD_LHB_LT|FAM.FD.LHB.LT]] || Lateral Habenula Lateral Part || excitatory-glu || [http://journal.frontiersin.org/article/10.3389/fnhum.2013.00826/full Regulation of the rapid eye movement (REM) sleep by habenular projection (LHT -> LHbL)]
|-
|  || [[BrainRegionFAM_FD_LHB_MED|FAM.FD.LHB.MED]] || Lateral Habenula Medial Part || excitatory-glu || [http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Both LHb and MHb control the dopaminergic and serotonergic systems (LHA -> LHbM)]
|-
| [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_PV|LAC.FD.HT.PV]] || Paraventricular Nucleus || excitatory-glu || [http://neuroscience.uth.tmc.edu/s4/chapter04.html Schematic of hypothalamic circuitry underlying satiety (LHA -> PVN)]
|-
| [[BrainAreaLMC|LMC]] || [[BrainRegionLMC_HL_RP_MG|LMC.HL.RP.MG]] || Raphe Magnus Nucleus || excitatory-glu || (unknown reference)
|-
| [[BrainAreaNDM|NDM]] || [[BrainRegionNDM_NC_AL_ROFCS|NDM.NC.AL.ROFCS]] || Sulcal Rostral Orbitofrontal Cortex || excitatory-glu || [http://www.nature.com/nrendo/journal/v6/n8/fig_tab/nrendo.2010.93_F1.html Bowels control brain: gut hormones and obesity (LHA -> OFC, abstract)]
|}

= Thirdparty Circuits =
(generated)

* [http://neuroscience.uth.tmc.edu/s4/images/dougherty/pdougherty4_3.jpg Schematic of hypothalamic circuitry underlying satiety] - see [http://neuroscience.uth.tmc.edu/s4/chapter04.html Reference]

<img src="http://neuroscience.uth.tmc.edu/s4/images/dougherty/pdougherty4_3.jpg" alt="unavailable">

* [http://www.nature.com/nrendo/journal/v6/n8/images/nrendo.2010.93-f1.jpg Bowels control brain: gut hormones and obesity] - see [http://www.nature.com/nrendo/journal/v6/n8/fig_tab/nrendo.2010.93_F1.html Reference]

<img src="http://www.nature.com/nrendo/journal/v6/n8/images/nrendo.2010.93-f1.jpg" alt="unavailable">

* [http://www.frontiersin.org/files/Articles/70852/fnhum-07-00826-HTML/image_m/fnhum-07-00826-g002.jpg Regulation of the rapid eye movement (REM) sleep by habenular projection] - see [http://journal.frontiersin.org/article/10.3389/fnhum.2013.00826/full Reference]

<img src="http://www.frontiersin.org/files/Articles/70852/fnhum-07-00826-HTML/image_m/fnhum-07-00826-g002.jpg" alt="unavailable">

* [http://www.nature.com/neuro/journal/v17/n9/images/nn.3779-F2.jpg Both LHb and MHb control the dopaminergic and serotonergic systems] - see [http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Reference]

<img src="http://www.nature.com/neuro/journal/v17/n9/images/nn.3779-F2.jpg" alt="unavailable">

* [http://www.nature.com/npp/journal/v35/n1/images/npp2009121f1.jpg Fear regulation] - see [https://brmlab.cz/project/brain_hacking/tdcs/pfc Reference]

<img src="http://www.nature.com/npp/journal/v35/n1/images/npp2009121f1.jpg" alt="unavailable">

* [http://dkqlgfb5sk2dk.cloudfront.net/content/ajpregu/302/2/R215/F1.large.jpg Glucose-sensing neural network] - see [http://ajpregu.physiology.org/content/302/2/R215 Reference]

<img src="http://dkqlgfb5sk2dk.cloudfront.net/content/ajpregu/302/2/R215/F1.large.jpg" alt="unavailable">

* [http://www.pnas.org/content/103/32/12150/F7.large.jpg Food-entrainable circadian oscillator] - see [http://www.pnas.org/content/103/32/12150/F7.expansion.html Reference]

<img src="http://www.pnas.org/content/103/32/12150/F7.large.jpg" alt="unavailable"height=300>

* [http://www.dana.org/uploadedImages/Images/Content_Images/SenBodyFunc2_PR2007_cont.jpg Eating and sleeping to survive] - see [http://www.dana.org/Publications/ReportDetails.aspx?id=44217 Reference]

<img src="http://www.dana.org/uploadedImages/Images/Content_Images/SenBodyFunc2_PR2007_cont.jpg" alt="unavailable">

* [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/intrahypothalamic.png Intrahypothalamic connections important for neural control of food intake and energy balance] - see [http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf Reference]

<img src="http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/intrahypothalamic.png" alt="unavailable">

* [http://d2avczb82rh8fa.cloudfront.net/content/jn/107/10/2633/F1.large.jpg Connectivity map of the habenula] - see [http://jn.physiology.org/content/107/10/2633 Reference]

<img src="http://d2avczb82rh8fa.cloudfront.net/content/jn/107/10/2633/F1.large.jpg" alt="unavailable">

* [http://sni.wpengine.com/wp-content/uploads/2015/05/3520/SNI-3-40-g001.png Amygdala and its network] - see [http://www.surgicalneurologyint.com/article.asp?issn=2152-7806;year=2012;volume=3;issue=2;spage=40;epage=46;aulast=Langevin Reference]

<img src="http://sni.wpengine.com/wp-content/uploads/2015/05/3520/SNI-3-40-g001.png" alt="unavailable">


= References =
(generated)

* http://neuroscience.uth.tmc.edu/s4/chapter04.html
* http://www.nature.com/nrendo/journal/v6/n8/fig_tab/nrendo.2010.93_F1.html
* http://journal.frontiersin.org/article/10.3389/fnhum.2013.00826/full
* http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html
* https://brmlab.cz/project/brain_hacking/tdcs/pfc
* http://ajpregu.physiology.org/content/302/2/R215
* http://www.pnas.org/content/103/32/12150/F7.expansion.html
* http://www.dana.org/Publications/ReportDetails.aspx?id=44217
* http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf
* http://jn.physiology.org/content/107/10/2633
* http://www.surgicalneurologyint.com/article.asp?issn=2152-7806;year=2012;volume=3;issue=2;spage=40;epage=46;aulast=Langevin