View source for BrainRegionFMM NC PH MEC


<pre style="color: green">Medial Entorhinal Cortex</pre>
@@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainAreaFMM]] -> [[BrainRegionFMM_NC_PH_MEC]]
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This page covers biological details of component Medial Entorhinal Cortex.
Region is part of aHuman target integrated biological model.

* '''Top-down path to region''': Cerebral Cortex -> Parahippocampal Lobe (NC.LOBE.PH) -> Anterior Parahippocampal Gyrus (FMM.NC.PHA) -> [[BrainCenterNC_PHA_RH|Rhinal Cortex]] (NC.PHA.RH) -> Entorhinal Cortex (FMM.NC.PH.ET) -> [[BrainRegionFMM_NC_PH_MEC|Medial Entorhinal Cortex]] (FMM.NC.PH.MEC) (see [[OverallMindMaps|Mind Maps]])
* '''Type''': cortex
* '''Brain area''': [[BrainAreaFMM|Forebrain - Memory Management Area]]
* '''Brodmann ID''': 28
* '''Role''': processor
* '''Function''': Memory consolidation, basic, view independent position
* '''Notes to function''': spatial input to HC; grid cells; path integration computations based on a global frame of reference, primarily using internally generated, self-motion cues and external input about environmental boundaries and scenes; provides hippocampus with coordinate system that underlies spatial context of experience
(generated)
= Components =
(generated)


* no child items defined

= Connectivity =
(generated)


http://ahuman.org/svn/ahwiki/images/dot/FMM.NC.PH.MEC.dot.png

'''Inbound Region Connections:'''

{| class=wikitable width=80%
| '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Reference'''
|-
| [[BrainAreaFMM|FMM]] || [[BrainRegionFMM_FT_HF_SUBD|FMM.FT.HF.SUBD]] || Distal Subiculum || excitatory-glu || [http://learnmem.cshlp.org/content/14/11/714/F1.expansion Attractor Network in Hippocampus (SUB -> EC, abstract)]
|-
|  || [[BrainRegionFMM_NC_PH_PAS|FMM.NC.PH.PAS]] || Parasubiculum || feedforward-glu || (unknown reference)
|-
|  || [[BrainRegionFMM_NC_PH_POR|FMM.NC.PH.POR]] || Postrhinal Cortex || feedforward-glu || [http://www.sciencedirect.com/science/article/pii/S0149763411001722 Entorhinal Cortex Inputs and Outputs (TFTH -> EC, abstract)]
|-
|  || [[BrainRegionFMM_NC_PH_POS|FMM.NC.PH.POS]] || Postsubiculum || feedforward-glu || [http://www.scholarpedia.org/article/Head_direction_cells Head Direction Cell Circuit (PSUB -> EC, abstract)]
|-
|  || [[BrainRegionFMM_NC_PH_PRS|FMM.NC.PH.PRS]] || Presubiculum || feedforward-glu || [http://learnmem.cshlp.org/content/14/11/714/F1.expansion Attractor Network in Hippocampus (PRESUB -> EC, abstract)]
|-
| [[BrainAreaNCP|NCP]] || [[BrainRegionNCP_NC_MPL_PSCG|NCP.NC.MPL.PSCG]] || Posterior Cingulate Cortex || feedforward-glu || [http://www.nature.com/nrn/journal/v3/n2/fig_tab/nrn726_F3.html McNaughton Spatial Processing Network (PCGRSP -> EnthCortex, abstract)]
|-
|  || [[BrainRegionNCP_NC_MPL_RSC|NCP.NC.MPL.RSC]] || Retrosplenial Cortex || feedforward-glu || [http://www.nature.com/nrn/journal/v3/n2/fig_tab/nrn726_F3.html McNaughton Spatial Processing Network (PCGRSP -> EnthCortex, abstract)]
|}

'''Outbound Region Connections:'''

{| class=wikitable width=80%
| '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Reference'''
|-
| [[BrainAreaFMM|FMM]] || [[BrainRegionFMM_FD_MB_MMB|FMM.FD.MB.MMB]] || Medial Mammillary Nucleus || excitatory-glu || [http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F2.html Mammillary bodies: two memory systems in one (MedialEC -> MMB, abstract)]
|-
|  || [[BrainRegionFMM_FD_TH_LD|FMM.FD.TH.LD]] || Lateral Dorsal Nucleus of Thalamus || excitatory-glu || [http://learnmem.cshlp.org/content/18/6/384/F1.expansion.html Contributions of Diencephalon to Recognition Memory (EC -> LD, abstract)]
|-
|  || [[BrainRegionFMM_FT_HC_CA1P|FMM.FT.HC.CA1P]] || Proximal CA1 of Hippocampus || excitatory-glu || [http://journal.frontiersin.org/Journal/10.3389/fpsyt.2013.00061/full Neuronal projections in the hippocampus (ET -> CA1, abstract)]
|-
|  || [[BrainRegionFMM_FT_HC_CA2|FMM.FT.HC.CA2]] || Dorsolateral Cornu Ammonis of Hippocampus || excitatory-glu || [http://www.surgicalneurologyint.com/article.asp?issn=2152-7806;year=2012;volume=3;issue=2;spage=40;epage=46;aulast=Langevin Amygdala and its network (EC -> HC, abstract)]
|-
|  || [[BrainRegionFMM_FT_HC_CA3D|FMM.FT.HC.CA3D]] || Distal CA3 of Hippocampus || excitatory-glu || [http://journal.frontiersin.org/Journal/10.3389/fpsyt.2013.00061/full Neuronal projections in the hippocampus (ET -> CA3, abstract)]
|-
|  || [[BrainRegionFMM_FT_HC_DG|FMM.FT.HC.DG]] || Dentate Gyrus || excitatory-glu || [http://journal.frontiersin.org/Journal/10.3389/fpsyt.2013.00061/full Neuronal projections in the hippocampus (ET -> DG, abstract)]
|}

= Thirdparty Circuits =
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* [http://learnmem.cshlp.org/content/18/6/384/F1.large.jpg Contributions of Diencephalon to Recognition Memory] - see [http://learnmem.cshlp.org/content/18/6/384/F1.expansion.html Reference]

<img src="http://learnmem.cshlp.org/content/18/6/384/F1.large.jpg" alt="unavailable">

* [http://www.nature.com/nrn/journal/v5/n1/images/nrn1299-f2.jpg Mammillary bodies: two memory systems in one] - see [http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F2.html Reference]

<img src="http://www.nature.com/nrn/journal/v5/n1/images/nrn1299-f2.jpg" alt="unavailable">

* [http://www.scholarpedia.org/w/images/6/63/Taube_Figure_5a.png Head Direction Cell Circuit] - see [http://www.scholarpedia.org/article/Head_direction_cells Reference]

<img src="http://www.scholarpedia.org/w/images/6/63/Taube_Figure_5a.png" alt="unavailable">

* [http://www.nature.com/nrn/journal/v3/n2/images/nrn726-f3.jpg McNaughton Spatial Processing Network] - see [http://www.nature.com/nrn/journal/v3/n2/fig_tab/nrn726_F3.html Reference]

<img src="http://www.nature.com/nrn/journal/v3/n2/images/nrn726-f3.jpg" alt="unavailable">

* [http://www.scholarpedia.org/w/images/thumb/f/f2/ITCortex_pathway.jpg/400px-ITCortex_pathway.jpg Visual Path to Hippocampus] - see [http://www.scholarpedia.org/article/Inferior_temporal_cortex Reference]

<img src="http://www.scholarpedia.org/w/images/thumb/f/f2/ITCortex_pathway.jpg/400px-ITCortex_pathway.jpg" alt="unavailable">

* [http://sni.wpengine.com/wp-content/uploads/2015/05/3520/SNI-3-40-g001.png Amygdala and its network] - see [http://www.surgicalneurologyint.com/article.asp?issn=2152-7806;year=2012;volume=3;issue=2;spage=40;epage=46;aulast=Langevin Reference]

<img src="http://sni.wpengine.com/wp-content/uploads/2015/05/3520/SNI-3-40-g001.png" alt="unavailable">

* [http://www.frontiersin.org/files/Articles/46459/fpsyt-04-00061-HTML/image_m/fpsyt-04-00061-g002.jpg Neuronal projections in the hippocampus] - see [http://journal.frontiersin.org/Journal/10.3389/fpsyt.2013.00061/full Reference]

<img src="http://www.frontiersin.org/files/Articles/46459/fpsyt-04-00061-HTML/image_m/fpsyt-04-00061-g002.jpg" alt="unavailable">


= References =
(generated)

* http://learnmem.cshlp.org/content/18/6/384/F1.expansion.html
* http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F2.html
* http://www.scholarpedia.org/article/Head_direction_cells
* http://www.nature.com/nrn/journal/v3/n2/fig_tab/nrn726_F3.html
* http://www.scholarpedia.org/article/Inferior_temporal_cortex
* http://www.surgicalneurologyint.com/article.asp?issn=2152-7806;year=2012;volume=3;issue=2;spage=40;epage=46;aulast=Langevin
* http://journal.frontiersin.org/Journal/10.3389/fpsyt.2013.00061/full