View source for BrainRegionFMM FT HC CA1D

<pre style="color: green">Distal CA1 of Hippocampus</pre>
@@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainAreaFMM]] -> [[BrainRegionFMM_FT_HC_CA1D]]
----

This page covers biological details of component Distal CA1 of Hippocampus.
Region is part of aHuman target integrated biological model.

* '''Top-down path to region''': Forebrain Telencephalon -> [[BrainCenterFMM_FT_HF|Hippocampal Formation]] (FMM.FT.HF) -> Hippocampus (FMM.FT.HC) -> Ventrolateral Cornu Ammonis of Hippocampus (FMM.FT.HC.CA1) -> [[BrainRegionFMM_FT_HC_CA1D|Distal CA1 of Hippocampus]] (FMM.FT.HC.CA1D) (see [[OverallMindMaps|Mind Maps]])
* '''Type''': cortex
* '''Quality''': L0
* '''Brain area''': [[BrainAreaFMM|Forebrain - Memory Management Area]]
* '''Role''': processor.memory.ca1
* '''Function''': Long-term memory, motivational
(generated)
= Components =
(generated)


* no child items defined

= Connectivity =
(generated)


http://ahuman.org/svn/ahwiki/images/dot/FMM.FT.HC.CA1D.dot.png

'''Inbound Region Connections:'''

{| class=wikitable width=80%
| '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Reference'''
|-
| [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FT_AM_BP|FAM.FT.AM.BP]] || Parvicellular Basal Amygdaloid Nucleus || excitatory-glu || [https://books.google.ru/books?id=P3fSBwAAQBAJ Detailed amygdalohippocampal projections (Bpc -> CA1D)]
|-
| [[BrainAreaFMM|FMM]] || [[BrainRegionFMM_FT_HC_CA2|FMM.FT.HC.CA2]] || Dorsolateral Cornu Ammonis of Hippocampus || excitatory-glu || [http://www.sciencedirect.com/science/article/pii/S030645220600755X Flow of impulses in hippocampal region (CA2 -> CA1, abstract)]
|-
|  || [[BrainRegionFMM_FT_HC_CA3P|FMM.FT.HC.CA3P]] || Proximal CA3 of Hippocampus || excitatory-glu || [http://journal.frontiersin.org/Journal/10.3389/fpsyt.2013.00061/full Neuronal projections in the hippocampus (CA3 -> CA1, abstract)]
|-
|  || [[BrainRegionFMM_NC_PH_LEC|FMM.NC.PH.LEC]] || Lateral Entorhinal Cortex || excitatory-glu || [http://journal.frontiersin.org/Journal/10.3389/fpsyt.2013.00061/full Neuronal projections in the hippocampus (ET -> CA1, abstract)]
|-
| [[BrainAreaLMC|LMC]] || [[BrainRegionLMC_MM_VTA|LMC.MM.VTA]] || Ventral Tegmental Area || modulatory-da || [http://neurowiki2012.wikispaces.com/Presynaptic+Mechanisms+of+Synaptic+Plasticity Reward circuit of human brain (VTA -> HC, abstract)]
|}

'''Outbound Region Connections:'''

{| class=wikitable width=80%
| '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Reference'''
|-
| [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FT_AM_LAVM|FAM.FT.AM.LAVM]] || Ventromedial Amygdaloid Nucleus || excitatory-glu || [https://brmlab.cz/project/brain_hacking/tdcs/pfc Fear regulation (Hippocampus -> LA, abstract)]
|-
|  || [[BrainRegionFAM_FT_SEP_LT|FAM.FT.SEP.LT]] || Lateral Septal Nucleus || excitatory-glu || [http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (Hippo -> Septum, abstract)]
|-
| [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_FT_ACC_CORE|FEC.FT.ACC.CORE]] || Nucleus Accumbens Core || excitatory-glu || [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/nucleus-accumbens.jpg Nucleus Accumbens (CA1 -> NACC, abstract)]
|-
| [[BrainAreaFMM|FMM]] || [[BrainRegionFMM_FT_HF_SUBP|FMM.FT.HF.SUBP]] || Proximal Subiculum || excitatory-glu || [http://learnmem.cshlp.org/content/14/11/714/F1.expansion Attractor Network in Hippocampus (CA1 -> SUB, abstract)]
|-
| [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_MPO|LAC.FD.HT.MPO]] || Median Preoptic Nucleus || excitatory-glu || [http://www.nature.com/nrn/journal/v5/n7 Feeling (HC -> HT, abstract)]
|-
| [[BrainAreaNDM|NDM]] || [[BrainRegionNDM_NC_AL_ROFCR|NDM.NC.AL.ROFCR]] || Most Rostral Orbitofrontal Cortex || excitatory-glu || [http://www.sciencedirect.com/science/article/pii/S030100820900183X Simplified model of hippocampal formation anatomy (CA1 -> mPFC, abstract)]
|-
|  || [[BrainRegionNDM_NC_AL_VMPFC|NDM.NC.AL.VMPFC]] || Ventromedial Prefrontal Cortex || excitatory-glu || [http://journal.frontiersin.org/article/10.3389/fncom.2011.00001/full Gating of medial prefrontal activity by the entorhinal cortex (HC -> MPFC, abstract)]
|}

= Thirdparty Circuits =
(generated)

* [http://ars.els-cdn.com/content/image/1-s2.0-S030100820900183X-gr4.jpg Simplified model of hippocampal formation anatomy] - see [http://www.sciencedirect.com/science/article/pii/S030100820900183X Reference] (CT.OPERATING-MODEL)

 Amyg=[[BrainCenterFAM_FT_AM|Amygdala,FAM.FT.AM]]
 CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]])
 CA3=Dorsomedial Cornu Ammonis of Hippocampus,FMM.FT.HC.CA3 (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]])
 DG=[[BrainRegionFMM_FT_HC_DG|Dentate Gyrus,FMM.FT.HC.DG]]
 EC=Entorhinal Cortex,FMM.NC.PH.ET (see [[BrainCenterNC_PHA_RH|Rhinal Cortex]])
 NACC=Accumbens Nucleus,FEC.FT.ACC (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 SUB=Subiculum,FMM.FT.HF.SUB (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]])
 mPFC=Orbitofrontal Cortex,NC.AL.OPFC (see [[BrainCenterNC_AL_OMPFC|Orbitomedial Prefrontal Cortex]])
<img src="http://ahuman.org/svn/ahwiki/images/ext/dadb137a040ae8763cae16e277d660cc.jpg" alt=alt="unavailable" style="max-width: 100%;">

* [http://www.scholarpedia.org/w/images/6/63/Taube_Figure_5a.png Head Direction Cell Circuit] - see [http://www.scholarpedia.org/article/Head_direction_cells Reference] (CT.HEAD-DIRECTION)

 AD=[[BrainRegionFMM_FD_TH_AD|Anterodorsal Nucleus,FMM.FD.TH.AD]]
 DTN=[[BrainRegionLMC_HT_TG_LDT|Laterodorsal Tegmental Nucleus,LMC.HT.TG.DTG]]
 EC=Entorhinal Cortex,FMM.NC.PH.ET (see [[BrainCenterNC_PHA_RH|Rhinal Cortex]])
 HC=Hippocampus,FMM.FT.HC (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]])
 IPD=[[BrainRegionFEC_HT_TG_IPD|Interpeduncular Nucleus,FEC.HT.TG.IPD]]
 LD=[[BrainRegionFMM_FD_TH_LD|Lateral Dorsal Nucleus of Thalamus,FMM.FD.TH.LD]]
 LHAB=[[BrainCenterFAM_FD_HB|Habenula,FAM.FD.HB]]
 LMB=[[BrainRegionFMM_FD_MB_LMB|Lateral Mammillary Nucleus,FMM.FD.MB.LMB]]
 MVSN=[[BrainRegionLPC_HT_MVBN|Medial Vestibular Nucleus,LPC.HT.MVBN]]
 NPRP=[[BrainRegionLRC_HL_NPH|Prepositus Nucleus,LRC.HL.NPH]]
 PC=Parietal Lobe,NC.LOBE.PAR
 PRHC=[[BrainRegionFMM_NC_PH_POR|Postrhinal Cortex,FMM.NC.PH.POR]]
 PSUB=[[BrainRegionFMM_NC_PH_POS|Postsubiculum,FMM.NC.PH.POS]]
 RSP=[[BrainRegionNCP_NC_MPL_RSC|Retrosplenial Cortex,NCP.NC.MPL.RSC]]
 SUPGEN=[[BrainRegionNSA_FD_TH_SG|Suprageniculate Nucleus of Thalamus,NSA.FD.TH.SG]]
 VC=[[BrainCenterNC_LOBE_OCC|Occipital Lobe,NC.LOBE.OCC]]
<img src="http://ahuman.org/svn/ahwiki/images/ext/1f4c1812ddb8ec93b53b4ed26dc3a381.png" alt=alt="unavailable" style="max-width: 100%;">

* [http://learnmem.cshlp.org/content/14/11/714/F1.large.jpg Attractor Network in Hippocampus] - see [http://learnmem.cshlp.org/content/14/11/714/F1.expansion Reference] (CT.ATTRACTOR-NETWORK)

 AN=Anterior Nucleus of Thalamus,FD.TH.AN (see [[BrainCenterFD_TH_CR|Cognitive Thalamus]])
 CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]])
 CA3=Dorsomedial Cornu Ammonis of Hippocampus,FMM.FT.HC.CA3 (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]])
 DG=[[BrainRegionFMM_FT_HC_DG|Dentate Gyrus,FMM.FT.HC.DG]]
 EC=Entorhinal Cortex,FMM.NC.PH.ET (see [[BrainCenterNC_PHA_RH|Rhinal Cortex]])
 MBIN=[[BrainRegionFMM_FD_MB_MMB|Medial Mammillary Nucleus,FMM.FD.MB.MMB]]
 MBOUT=[[BrainRegionFMM_FD_MB_LMB|Lateral Mammillary Nucleus,FMM.FD.MB.LMB]]
 NACC=Accumbens Nucleus,FEC.FT.ACC (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 PERI=[[BrainRegionFMM_NC_PH_PER|Perirhinal Cortex,FMM.NC.PH.PER]]
 PRESUB=[[BrainRegionFMM_NC_PH_PRS|Presubiculum,FMM.NC.PH.PRS]]
 SEP=[[BrainCenterFAM_FT_SEP|Septal Nuclei,FAM.FT.SEP]]
 SUB=Subiculum,FMM.FT.HF.SUB (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]])
<img src="http://ahuman.org/svn/ahwiki/images/ext/fe6b169088a7e187f94593c41d180791.jpg" alt=alt="unavailable" style="max-width: 100%;" height=600 width=600>

* [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/nucleus-accumbens.jpg Nucleus Accumbens] (unknown reference) (CF.NUCLEUUS-ACCUMBENS)

 CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]])
 CA3=Dorsomedial Cornu Ammonis of Hippocampus,FMM.FT.HC.CA3 (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]])
 EC=Entorhinal Cortex,FMM.NC.PH.ET (see [[BrainCenterNC_PHA_RH|Rhinal Cortex]])
 NACC=Accumbens Nucleus,FEC.FT.ACC (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 PAS=[[BrainRegionFMM_NC_PH_PAS|Parasubiculum,FMM.NC.PH.PAS]]
 PRR=[[BrainRegionFMM_NC_PH_PER|Perirhinal Cortex,FMM.NC.PH.PER]]
 SUB=Subiculum,FMM.FT.HF.SUB (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]])
<img src="http://ahuman.org/svn/ahwiki/images/ext/61315b42c434b6f82081632f705a444d.jpg" alt=alt="unavailable" style="max-width: 100%;">

* [http://d2avczb82rh8fa.cloudfront.net/content/jn/107/10/2633/F1.large.jpg Connectivity map of the habenula] - see [http://jn.physiology.org/content/107/10/2633 Reference] (CF.HB-CONN)

 CPu=Striatum,FEC.FT.ST (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 EP=[[BrainRegionFAM_FT_EPF|Endopiriform Nucleus,FAM.FT.EPF]]
 Hippo=Hippocampus,FMM.FT.HC (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]])
 IPN=[[BrainRegionFEC_HT_TG_IPD|Interpeduncular Nucleus,FEC.HT.TG.IPD]]
 L=Lateral Habenula,FAM.FD.LHB (see [[BrainCenterFAM_FD_HB|Habenula]])
 LH=[[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]]
 M=[[BrainRegionFAM_FD_MHB|Medial Habenula,FAM.FD.MHB]]
 NAc=Accumbens Nucleus,FEC.FT.ACC (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 PAG=[[BrainRegionLMC_MM_PAG|Periaqueductal Gray Matter,LMC.MM.PAG]]
 Raphe=Raphe Nuclei of Medulla,LMC.HL.RP (see [[BrainCenterHL_RF|Medullary Reticular Formation]])
 SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 Septum=[[BrainCenterFAM_FT_SEP|Septal Nuclei,FAM.FT.SEP]]
 VTA=[[BrainRegionLMC_MM_VTA|Ventral Tegmental Area,LMC.MM.VTA]]
<img src="http://ahuman.org/svn/ahwiki/images/ext/213e030f063f9640f8ace79244e622d1.jpg" alt=alt="unavailable" style="max-width: 100%;">

* [http://www.nature.com/nrn/journal/v5/n7/images/nrn1432-f2.jpg Feeling] - see [http://www.nature.com/nrn/journal/v5/n7 Reference] (CF.FEELING)

 AN=Anterior Nucleus of Thalamus,FD.TH.AN (see [[BrainCenterFD_TH_CR|Cognitive Thalamus]])
 CG=[[BrainRegionNCP_NC_MPL_PSCG|Posterior Cingulate Cortex,NCP.NC.MPL.PSCG]]
 HC=Hippocampus,FMM.FT.HC (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]])
 HT=[[BrainCenterFD_HT|Hypothalamus,FD.HT]]
<img src="http://ahuman.org/svn/ahwiki/images/ext/739bae9479f0b9abd97f4fa36e001aff.jpg" alt=alt="unavailable" style="max-width: 100%;">

* [http://www.nature.com/npp/journal/v35/n1/images/npp2009121f1.jpg Fear regulation] - see [https://brmlab.cz/project/brain_hacking/tdcs/pfc Reference] (CF.FEAR-REG)

 B=Basal Amygdaloid Nucleus,FAM.FT.AM.B (see [[BrainCenterFAM_FT_AM|Amygdala]])
 CE=Central Amygdala,FAM.FT.AM.CEA (see [[BrainCenterFAM_FT_AM|Amygdala]])
 Hippocampus=Hippocampus,FMM.FT.HC (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]])
 Hypothalamus=[[BrainCenterFD_HT|Hypothalamus,FD.HT]]
 ITC=[[BrainRegionFAM_FT_AM_ITC|Intercalated Amygdaloid Nuclei,FAM.FT.AM.ITC]]
 LA=Lateral Amygdaloid Nucleus,FAM.FT.AM.LA (see [[BrainCenterFAM_FT_AM|Amygdala]])
 Striatum=Striatum,FEC.FT.ST (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 dlPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see [[BrainCenterNC_AL_LPFC|Lateral Prefrontal Cortex]])
 vmPFC=[[BrainRegionNDM_NC_AL_VMPFC|Ventromedial Prefrontal Cortex,NDM.NC.AL.VMPFC]]
<img src="http://ahuman.org/svn/ahwiki/images/ext/0109abd5f9ba228b2df07c466da4b771.jpg" alt=alt="unavailable" style="max-width: 100%;">

* [http://www.frontiersin.org/files/Articles/1854/fncom-05-00001-HTML/image_m/fncom-05-00001-g006.jpg Gating of medial prefrontal activity by the entorhinal cortex] - see [http://journal.frontiersin.org/article/10.3389/fncom.2011.00001/full Reference] (CF.EC-MPFC)

 EC=Entorhinal Cortex,FMM.NC.PH.ET (see [[BrainCenterNC_PHA_RH|Rhinal Cortex]])
 HC=Hippocampus,FMM.FT.HC (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]])
 MPFC=Medial Prefrontal Cortex,NC.AL.MPFC (see [[BrainCenterNC_AL_OMPFC|Orbitomedial Prefrontal Cortex]])
<img src="http://ahuman.org/svn/ahwiki/images/ext/a5a2fdaa7255e8a7c7262baa9b528b90.jpg" alt=alt="unavailable" style="max-width: 100%;">

* [http://sni.wpengine.com/wp-content/uploads/2015/05/3520/SNI-3-40-g001.png Amygdala and its network] - see [http://www.surgicalneurologyint.com/article.asp?issn=2152-7806;year=2012;volume=3;issue=2;spage=40;epage=46;aulast=Langevin Reference] (CF.AM-NET)

 BLN=[[BrainRegionFAM_FT_AM_BP|Parvicellular Basal Amygdaloid Nucleus,FAM.FT.AM.BP]]
 CEA=Central Amygdala,FAM.FT.AM.CEA (see [[BrainCenterFAM_FT_AM|Amygdala]])
 EC=Entorhinal Cortex,FMM.NC.PH.ET (see [[BrainCenterNC_PHA_RH|Rhinal Cortex]])
 HC=Hippocampus,FMM.FT.HC (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]])
 HTS=[[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]]
 ITC=[[BrainRegionNSA_NC_IT_TE|Inferotemporal Cortex,NSA.NC.IT.TE]]
 LA=Lateral Amygdaloid Nucleus,FAM.FT.AM.LA (see [[BrainCenterFAM_FT_AM|Amygdala]])
 LHB=Lateral Habenula,FAM.FD.LHB (see [[BrainCenterFAM_FD_HB|Habenula]])
 MD=Mediodorsal Nucleus of Thalamus,FD.TH.MD (see [[BrainCenterFD_TH_CR|Cognitive Thalamus]])
 MPFC=[[BrainCenterNC_AL_OMPFC|Orbitomedial Prefrontal Cortex,NC.AL.OMPFC]]
 NACC=Accumbens Nucleus,FEC.FT.ACC (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 PAG=[[BrainRegionLMC_MM_PAG|Periaqueductal Gray Matter,LMC.MM.PAG]]
 RMTG=[[BrainRegionFEC_HT_TG_RMTG|Rostromedial Tegmental Nucleus,FEC.HT.TG.RMTG]]
 STC=[[BrainRegionNSA_NC_STG_A3|Wernicke's area A3,NSA.NC.STG.A3]]
 VGDM=[[BrainRegionLAC_HL_VGN|Vagus Nucleus,LAC.HL.VGN]]
 VTA=[[BrainRegionLMC_MM_VTA|Ventral Tegmental Area,LMC.MM.VTA]]
<img src="http://ahuman.org/svn/ahwiki/images/ext/148ecc584cca86040df3ac88ecdbcba6.png" alt=alt="unavailable" style="max-width: 100%;">

* [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/am/hippocampo-amygdala-projections.png Detailed amygdalohippocampal projections] - see [https://books.google.ru/books?id=P3fSBwAAQBAJ Reference] (CF.AM-HC-DET)

 ABmg=[[BrainRegionFAM_FT_AM_AB|Accessory Basal Amygdaloid Nucleus,FAM.FT.AM.AB]]
 Bmg=[[BrainRegionFAM_FT_AM_BM|Magnocellular Basal Amygdaloid Nucleus,FAM.FT.AM.BM]]
 Bpc=[[BrainRegionFAM_FT_AM_BP|Parvicellular Basal Amygdaloid Nucleus,FAM.FT.AM.BP]]
 CA1D=[[BrainRegionFMM_FT_HC_CA1D|Distal CA1 of Hippocampus,FMM.FT.HC.CA1D]]
 CA1P=[[BrainRegionFMM_FT_HC_CA1P|Proximal CA1 of Hippocampus,FMM.FT.HC.CA1P]]
 L=Lateral Amygdaloid Nucleus,FAM.FT.AM.LA (see [[BrainCenterFAM_FT_AM|Amygdala]])
 PaS=[[BrainRegionFMM_NC_PH_PAS|Parasubiculum,FMM.NC.PH.PAS]]
 PrS=[[BrainRegionFMM_NC_PH_PRS|Presubiculum,FMM.NC.PH.PRS]]
<img src="http://ahuman.org/svn/ahwiki/images/ext/3121df9834588ca3e60638859e5381a2.png" alt=alt="unavailable" style="max-width: 100%;">


= References =
(generated)

* http://www.sciencedirect.com/science/article/pii/S030100820900183X
* http://www.scholarpedia.org/article/Head_direction_cells
* http://learnmem.cshlp.org/content/14/11/714/F1.expansion
* http://jn.physiology.org/content/107/10/2633
* http://www.nature.com/nrn/journal/v5/n7
* https://brmlab.cz/project/brain_hacking/tdcs/pfc
* http://journal.frontiersin.org/article/10.3389/fncom.2011.00001/full
* http://www.surgicalneurologyint.com/article.asp?issn=2152-7806;year=2012;volume=3;issue=2;spage=40;epage=46;aulast=Langevin
* https://books.google.ru/books?id=P3fSBwAAQBAJ