View source for BrainRegionLAC FD HT AR

<pre style="color: green">Arcuate Nucleus of Hypothalamus</pre>
@@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainAreaLAC]] -> [[BrainRegionLAC_FD_HT_AR]]
----

This page covers biological details of component Arcuate Nucleus of Hypothalamus.
Region is part of aHuman target integrated biological model.

* '''Top-down path to region''': Forebrain Diencephalon -> [[BrainCenterFD_HT|Hypothalamus]] (FD.HT) -> Anterior Hypothalamus Area (LAC.FD.HT.AHT) -> Tuberal Area (LAC.FD.HT.TUB) -> [[BrainRegionLAC_FD_HT_AR|Arcuate Nucleus of Hypothalamus]] (LAC.FD.HT.AR) (see [[OverallMindMaps|Mind Maps]])
* '''Type''': nucleus
* '''Brain area''': [[BrainAreaLAC|Lower Brain - Autonomous Control Area]]
* '''Role''': processor.autonomic
* '''Function''': Regulation of growth, appetite and body weight
* '''Notes to function''': 
** lateral of tuberlulum, TIDA - releases dopamine to regulate secretion of prolactin hormone, GHRH - stimulate growth hormone secretion (ventrolateral)
(generated)
= Components =
(generated)


* no child items defined

= Connectivity =
(generated)


http://ahuman.org/svn/ahwiki/images/dot/LAC.FD.HT.AR.dot.png

'''Inbound Region Connections:'''
* no connections

'''Outbound Region Connections:'''

{| class=wikitable width=80%
| '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Reference'''
|-
| [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_DM|LAC.FD.HT.DM]] || Dorsomedial Hypothalamic Nucleus || excitatory-glu || [http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf Intrahypothalamic connections important for neural control of food intake and energy balance (ARC -> DMN)]
|-
|  || [[BrainRegionLAC_FD_HT_LTN|LAC.FD.HT.LTN]] || Lateral Hypothalamic Nucleus || excitatory-glu || [http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf Intrahypothalamic connections important for neural control of food intake and energy balance (ARC -> LHA)]
|-
|  || [[BrainRegionLAC_FD_HT_PV|LAC.FD.HT.PV]] || Paraventricular Nucleus || excitatory-glu || [http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf Intrahypothalamic connections important for neural control of food intake and energy balance (ARC -> PA)]
|-
|  || [[BrainRegionLAC_FD_HT_VM|LAC.FD.HT.VM]] || Ventromedial Hypothalamic Nucleus || excitatory-glu || [http://neuroscience.uth.tmc.edu/s4/chapter04.html Schematic of hypothalamic circuitry underlying satiety (ARC -> VMH)]
|-
| [[BrainAreaTEA|TEA]] || [[BrainRegionTARGET_TEA_ENDOCRINE|TARGET.TEA.ENDOCRINE]] || Endocrine Glands || endocrine-adenohypophysis || (unknown reference)
|}

= Thirdparty Circuits =
(generated)

* [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/intrahypothalamic.png Intrahypothalamic connections important for neural control of food intake and energy balance] - see [http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf Reference] (CL.INTRAHYPOTHALAMIC)

 AH=[[BrainRegionLAC_FD_HT_AH|Anterior Hypothalamic Nucleus,LAC.FD.HT.AH]]
 ARC=[[BrainRegionLAC_FD_HT_AR|Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR]]
 DMN=[[BrainRegionLAC_FD_HT_DM|Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM]]
 LHA=[[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]]
 MPOA=[[BrainRegionLAC_FD_HT_MPO|Median Preoptic Nucleus,LAC.FD.HT.MPO]]
 PA=[[BrainRegionLAC_FD_HT_PV|Paraventricular Nucleus,LAC.FD.HT.PV]]
 SCH=[[BrainRegionLAC_FD_HT_SCN|Suprachiasmatic Nucleus,LAC.FD.HT.SCN]]
 SON=[[BrainRegionLAC_FD_HT_SO|Supraoptic Nucleus,LAC.FD.HT.SO]]
 VMN=[[BrainRegionLAC_FD_HT_VM|Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM]]
<img src="http://ahuman.org/svn/ahwiki/images/ext/812cda92ff47d048aeb22ce670a9a9fb.png" alt=alt="unavailable" style="max-width: 100%;">

* [http://neuroscience.uth.tmc.edu/s4/images/dougherty/pdougherty4_3.jpg Schematic of hypothalamic circuitry underlying satiety] - see [http://neuroscience.uth.tmc.edu/s4/chapter04.html Reference] (CP.SATIETY)

 ARC=[[BrainRegionLAC_FD_HT_AR|Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR]]
 DMH=[[BrainRegionLAC_FD_HT_DM|Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM]]
 LHA=[[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]]
 NTS=[[BrainRegionLPC_HL_SOL|Solitary Nucleus,LPC.HL.SOL]]
 PVN=[[BrainRegionLAC_FD_HT_PV|Paraventricular Nucleus,LAC.FD.HT.PV]]
 VMH=[[BrainRegionLAC_FD_HT_VM|Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM]]
<img src="http://ahuman.org/svn/ahwiki/images/ext/6f1f0e26e147b046d3567a72e62038bb.jpg" alt=alt="unavailable" style="max-width: 100%;">

* [http://dkqlgfb5sk2dk.cloudfront.net/content/ajpregu/302/2/R215/F1.large.jpg Glucose-sensing neural network] - see [http://ajpregu.physiology.org/content/302/2/R215 Reference] (CP.GLUCOSE)

 ARC=[[BrainRegionLAC_FD_HT_AR|Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR]]
 DMN=[[BrainRegionLAC_FD_HT_DM|Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM]]
 LHA=[[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]]
 PVH=[[BrainRegionLAC_FD_HT_PV|Paraventricular Nucleus,LAC.FD.HT.PV]]
 VMH=[[BrainRegionLAC_FD_HT_VM|Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM]]
<img src="http://ahuman.org/svn/ahwiki/images/ext/0cd27888f0cfd10857510d32768c3815.jpg" alt=alt="unavailable" style="max-width: 100%;">

* [http://www.dana.org/uploadedImages/Images/Content_Images/SenBodyFunc2_PR2007_cont.jpg Eating and sleeping to survive] - see [http://www.dana.org/Publications/ReportDetails.aspx?id=44217 Reference] (CP.DMH-CYCLES)

 ARC=[[BrainRegionLAC_FD_HT_AR|Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR]]
 DMH=[[BrainRegionLAC_FD_HT_DM|Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM]]
 LHA=[[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]]
 MPO=[[BrainRegionLAC_FD_HT_MPO|Median Preoptic Nucleus,LAC.FD.HT.MPO]]
 PVH=[[BrainRegionLAC_FD_HT_PV|Paraventricular Nucleus,LAC.FD.HT.PV]]
 SCN=[[BrainRegionLAC_FD_HT_SCN|Suprachiasmatic Nucleus,LAC.FD.HT.SCN]]
 VLPO=[[BrainRegionLAC_FD_HT_VLPO|Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO]]
 VMH=[[BrainRegionLAC_FD_HT_VM|Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM]]
<img src="http://ahuman.org/svn/ahwiki/images/ext/aaf05c2cb0453d5f112754ade7c03956.jpg" alt=alt="unavailable" style="max-width: 100%;">

* [http://www.nature.com/nrendo/journal/v6/n8/images/nrendo.2010.93-f1.jpg Bowels control brain: gut hormones and obesity] - see [http://www.nature.com/nrendo/journal/v6/n8/fig_tab/nrendo.2010.93_F1.html Reference] (CP.BOWELS)

 AMY=[[BrainCenterFAM_FT_AM|Amygdala,FAM.FT.AM]]
 ARC=[[BrainRegionLAC_FD_HT_AR|Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR]]
 DS=Dorsal Striatum,FEC.FT.DST (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 LHA=[[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]]
 ME=[[BrainRegionTARGET_TEA_ENDOCRINE|Endocrine Glands,TARGET.TEA.ENDOCRINE]]
 NAc=Accumbens Nucleus,FEC.FT.ACC (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 NTS=[[BrainRegionLPC_HL_SOL|Solitary Nucleus,LPC.HL.SOL]]
 OFC=Orbitofrontal Cortex,NC.AL.OPFC (see [[BrainCenterNC_AL_OMPFC|Orbitomedial Prefrontal Cortex]])
 PBN=[[BrainRegionLPC_HT_PRF_PB|Parabrachial Nucleus,LPC.HT.PRF.PB]]
 PVN=[[BrainRegionLAC_FD_HT_PV|Paraventricular Nucleus,LAC.FD.HT.PV]]
 VMN=[[BrainRegionLAC_FD_HT_VM|Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM]]
 VTA=[[BrainRegionLMC_MM_VTA|Ventral Tegmental Area,LMC.MM.VTA]]
<img src="http://ahuman.org/svn/ahwiki/images/ext/1550acf4cfac7352ce9d8ba11a39c4e6.jpg" alt=alt="unavailable" style="max-width: 100%;">


= References =
(generated)

* http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf
* http://neuroscience.uth.tmc.edu/s4/chapter04.html
* http://ajpregu.physiology.org/content/302/2/R215
* http://www.dana.org/Publications/ReportDetails.aspx?id=44217
* http://www.nature.com/nrendo/journal/v6/n8/fig_tab/nrendo.2010.93_F1.html