View source for BrainRegionFMM FT HC CA1P

<pre style="color: green">Proximal CA1 of Hippocampus</pre>
@@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainAreaFMM]] -> [[BrainRegionFMM_FT_HC_CA1P]]
----

This page covers biological details of component Proximal CA1 of Hippocampus.
Region is part of aHuman target integrated biological model.

* '''Top-down path to region''': Forebrain Telencephalon -> [[BrainCenterFMM_FT_HF|Hippocampal Formation]] (FMM.FT.HF) -> Hippocampus (FMM.FT.HC) -> Ventrolateral Cornu Ammonis of Hippocampus (FMM.FT.HC.CA1) -> [[BrainRegionFMM_FT_HC_CA1P|Proximal CA1 of Hippocampus]] (FMM.FT.HC.CA1P) (see [[OverallMindMaps|Mind Maps]])
* '''Type''': cortex
* '''Brain area''': [[BrainAreaFMM|Forebrain - Memory Management Area]]
* '''Role''': processor.memory.ca1
* '''Function''': Long-term memory, spatial
(generated)
= Components =
(generated)


* no child items defined

= Connectivity =
(generated)


http://ahuman.org/svn/ahwiki/images/dot/FMM.FT.HC.CA1P.dot.png

'''Inbound Region Connections:'''

{| class=wikitable width=80%
| '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Reference'''
|-
| [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FT_AM_AB|FAM.FT.AM.AB]] || Accessory Basal Amygdaloid Nucleus || excitatory-glu || [https://books.google.ru/books?id=P3fSBwAAQBAJ Detailed amygdalohippocampal projections (ABmg -> CA1P)]
|-
| [[BrainAreaFMM|FMM]] || [[BrainRegionFMM_FD_TH_AV|FMM.FD.TH.AV]] || Anteroventral Nucleus || excitatory-glu || [http://learnmem.cshlp.org/content/18/6/384/F1.expansion.html Contributions of Diencephalon to Recognition Memory (AN -> HC, abstract)]
|-
|  || [[BrainRegionFMM_FD_TH_LD|FMM.FD.TH.LD]] || Lateral Dorsal Nucleus of Thalamus || excitatory-glu || [http://learnmem.cshlp.org/content/18/6/384/F1.expansion.html Contributions of Diencephalon to Recognition Memory (LD -> HC, abstract)]
|-
|  || [[BrainRegionFMM_FT_HC_CA2|FMM.FT.HC.CA2]] || Dorsolateral Cornu Ammonis of Hippocampus || excitatory-glu || [http://www.sciencedirect.com/science/article/pii/S030645220600755X Flow of impulses in hippocampal region (CA2 -> CA1, abstract)]
|-
|  || [[BrainRegionFMM_FT_HC_CA3D|FMM.FT.HC.CA3D]] || Distal CA3 of Hippocampus || excitatory-glu || [http://journal.frontiersin.org/Journal/10.3389/fpsyt.2013.00061/full Neuronal projections in the hippocampus (CA3 -> CA1, abstract)]
|-
|  || [[BrainRegionFMM_NC_PH_MEC|FMM.NC.PH.MEC]] || Medial Entorhinal Cortex || excitatory-glu || [http://journal.frontiersin.org/Journal/10.3389/fpsyt.2013.00061/full Neuronal projections in the hippocampus (ET -> CA1, abstract)]
|-
| [[BrainAreaNCP|NCP]] || [[BrainRegionNCP_NC_MPL_PSCG|NCP.NC.MPL.PSCG]] || Posterior Cingulate Cortex || excitatory-glu || [http://www.nature.com/nrn/journal/v5/n7 Feeling (CG -> HC, abstract)]
|-
|  || [[BrainRegionNCP_NC_MPL_RSC|NCP.NC.MPL.RSC]] || Retrosplenial Cortex || excitatory-glu || [https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 Prefrontal Cortex (PFC) in emotional behavior (PCA -> HCA, abstract)]
|-
| [[BrainAreaNPE|NPE]] || [[BrainRegionNPE_NC_IPL_MST|NPE.NC.IPL.MST]] || Medial Superior Temporal Area || excitatory-glu || [http://www.sciencedirect.com/science/article/pii/S0149763409002061 Contribution of hippocampal region CA3 to consciousness (IPL -> CA1, abstract)]
|}

'''Outbound Region Connections:'''

{| class=wikitable width=80%
| '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Reference'''
|-
| [[BrainAreaFMM|FMM]] || [[BrainRegionFMM_FD_MB_MMB|FMM.FD.MB.MMB]] || Medial Mammillary Nucleus || excitatory-glu || [http://www.nature.com/nrn/journal/v5/n7 Feeling (HC -> HT, abstract)]
|-
|  || [[BrainRegionFMM_FT_HF_SUBD|FMM.FT.HF.SUBD]] || Distal Subiculum || excitatory-glu || [http://learnmem.cshlp.org/content/14/11/714/F1.expansion Attractor Network in Hippocampus (CA1 -> SUB, abstract)]
|-
|  || [[BrainRegionFMM_NC_PH_PAS|FMM.NC.PH.PAS]] || Parasubiculum || excitatory-glu || (unknown reference)
|-
|  || [[BrainRegionFMM_NC_PH_POR|FMM.NC.PH.POR]] || Postrhinal Cortex || excitatory-glu || [http://www.sciencedirect.com/science/article/pii/S0149763411001722 Entorhinal Cortex Inputs and Outputs (CA1 -> TFTH, abstract)]
|-
| [[BrainAreaNDM|NDM]] || [[BrainRegionNDM_NC_AL_DMPFC|NDM.NC.AL.DMPFC]] || Dorsomedial Prefrontal Cortex || excitatory-glu || [http://journal.frontiersin.org/article/10.3389/fncom.2011.00001/full Gating of medial prefrontal activity by the entorhinal cortex (HC -> MPFC, abstract)]
|}

= Thirdparty Circuits =
(generated)

* [http://www.nature.com/nrn/journal/v5/n1/images/nrn1299-f4.jpg Medial mammillary nucleus and theta rhythm] - see [http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F4.html Reference] (CT.MMB-THETA)

 AVTH=[[BrainRegionFMM_FD_TH_AV|Anteroventral Nucleus,FMM.FD.TH.AV]]
 HF=[[BrainCenterFMM_FT_HF|Hippocampal Formation,FMM.FT.HF]]
 MMB=[[BrainRegionFMM_FD_MB_MMB|Medial Mammillary Nucleus,FMM.FD.MB.MMB]]
 RSP=[[BrainRegionNCP_NC_MPL_RSC|Retrosplenial Cortex,NCP.NC.MPL.RSC]]
 SEP=[[BrainCenterFAM_FT_SEP|Septal Nuclei,FAM.FT.SEP]]
 SupraMM=[[BrainRegionLAC_FD_HT_SUM|Supramammillary Nucleus,LAC.FD.HT.SUM]]
 VTN=[[BrainRegionLMC_MM_VTA|Ventral Tegmental Area,LMC.MM.VTA]]
<img src="http://ahuman.org/svn/ahwiki/images/ext/111fc1b02f4b92516dc6ba2b8dc06e0d.jpg" alt=alt="unavailable" style="max-width: 100%;">

* [http://www.scholarpedia.org/w/images/6/63/Taube_Figure_5a.png Head Direction Cell Circuit] - see [http://www.scholarpedia.org/article/Head_direction_cells Reference] (CT.HEAD-DIRECTION)

 AD=[[BrainRegionFMM_FD_TH_AD|Anterodorsal Nucleus,FMM.FD.TH.AD]]
 DTN=[[BrainRegionLMC_HT_TG_LDT|Laterodorsal Tegmental Nucleus,LMC.HT.TG.DTG]]
 EC=Entorhinal Cortex,FMM.NC.PH.ET (see [[BrainCenterNC_PHA_RH|Rhinal Cortex]])
 HC=Hippocampus,FMM.FT.HC (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]])
 IPD=[[BrainRegionFEC_HT_TG_IPD|Interpeduncular Nucleus,FEC.HT.TG.IPD]]
 LD=[[BrainRegionFMM_FD_TH_LD|Lateral Dorsal Nucleus of Thalamus,FMM.FD.TH.LD]]
 LHAB=[[BrainCenterFAM_FD_HB|Habenula,FAM.FD.HB]]
 LMB=[[BrainRegionFMM_FD_MB_LMB|Lateral Mammillary Nucleus,FMM.FD.MB.LMB]]
 MVSN=[[BrainRegionLPC_HT_MVBN|Medial Vestibular Nucleus,LPC.HT.MVBN]]
 NPRP=[[BrainRegionLRC_HL_NPH|Prepositus Nucleus,LRC.HL.NPH]]
 PC=Parietal Lobe,NC.LOBE.PAR
 PRHC=[[BrainRegionFMM_NC_PH_POR|Postrhinal Cortex,FMM.NC.PH.POR]]
 PSUB=[[BrainRegionFMM_NC_PH_POS|Postsubiculum,FMM.NC.PH.POS]]
 RSP=[[BrainRegionNCP_NC_MPL_RSC|Retrosplenial Cortex,NCP.NC.MPL.RSC]]
 SUPGEN=[[BrainRegionNSA_FD_TH_SG|Suprageniculate Nucleus of Thalamus,NSA.FD.TH.SG]]
 VC=[[BrainCenterNC_LOBE_OCC|Occipital Lobe,NC.LOBE.OCC]]
<img src="http://ahuman.org/svn/ahwiki/images/ext/1f4c1812ddb8ec93b53b4ed26dc3a381.png" alt=alt="unavailable" style="max-width: 100%;">

* [http://media.wiley.com/mrw_images/compphys/articles/cp010508/image_n/ncp01050839.jpg Entorhinal Cortex Inputs and Outputs] - see [http://www.sciencedirect.com/science/article/pii/S0149763411001722 Reference] (CT.ENTORHINAL-CORTEX)

 CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]])
 EC=Entorhinal Cortex,FMM.NC.PH.ET (see [[BrainCenterNC_PHA_RH|Rhinal Cortex]])
 TFTH=[[BrainRegionFMM_NC_PH_POR|Postrhinal Cortex,FMM.NC.PH.POR]]
<img src="http://ahuman.org/svn/ahwiki/images/ext/8c59021eebc110403d093cb1f7d2c6cf.jpg" alt=alt="unavailable" style="max-width: 100%;">

* [http://learnmem.cshlp.org/content/14/11/714/F1.large.jpg Attractor Network in Hippocampus] - see [http://learnmem.cshlp.org/content/14/11/714/F1.expansion Reference] (CT.ATTRACTOR-NETWORK)

 AN=Anterior Nucleus of Thalamus,FD.TH.AN (see [[BrainCenterFD_TH_CR|Cognitive Thalamus]])
 CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]])
 CA3=Dorsomedial Cornu Ammonis of Hippocampus,FMM.FT.HC.CA3 (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]])
 DG=[[BrainRegionFMM_FT_HC_DG|Dentate Gyrus,FMM.FT.HC.DG]]
 EC=Entorhinal Cortex,FMM.NC.PH.ET (see [[BrainCenterNC_PHA_RH|Rhinal Cortex]])
 MBIN=[[BrainRegionFMM_FD_MB_MMB|Medial Mammillary Nucleus,FMM.FD.MB.MMB]]
 MBOUT=[[BrainRegionFMM_FD_MB_LMB|Lateral Mammillary Nucleus,FMM.FD.MB.LMB]]
 NACC=Accumbens Nucleus,FEC.FT.ACC (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 PERI=[[BrainRegionFMM_NC_PH_PER|Perirhinal Cortex,FMM.NC.PH.PER]]
 PRESUB=[[BrainRegionFMM_NC_PH_PRS|Presubiculum,FMM.NC.PH.PRS]]
 SEP=[[BrainCenterFAM_FT_SEP|Septal Nuclei,FAM.FT.SEP]]
 SUB=Subiculum,FMM.FT.HF.SUB (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]])
<img src="http://ahuman.org/svn/ahwiki/images/ext/fe6b169088a7e187f94593c41d180791.jpg" alt=alt="unavailable" style="max-width: 100%;">

* [http://www.nature.com/nrn/journal/v3/n2/images/nrn726-f3.jpg McNaughton Spatial Processing Network] - see [http://www.nature.com/nrn/journal/v3/n2/fig_tab/nrn726_F3.html Reference] (CP.VISUAL-SPATIAL-PROCESSING)

 EnthCortex=Entorhinal Cortex,FMM.NC.PH.ET (see [[BrainCenterNC_PHA_RH|Rhinal Cortex]])
 HF=[[BrainCenterFMM_FT_HF|Hippocampal Formation,FMM.FT.HF]]
 ITCortex=[[BrainCenterNSA_NC_IT|Inferotemporal Area,NSA.NC.IT]]
 PCGRSP=[[BrainCenterNC_MPL|Medial Parietal Lobule,NC.MPL]]
 ParInsVestCortex=[[BrainRegionNSA_NC_IPS_VIP|Ventral Intraparietal Sulcus,NSA.NC.IPS.VIP]]
 PosteriorParietalCortex=[[BrainRegionNPE_NC_SPL_PG|Caudal Precuneus,NPE.NC.SPL.PG]]
 SUB=Subiculum,FMM.FT.HF.SUB (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]])
 SomSensCortex=[[BrainRegionNCP_NC_PG_S1|Primary Somatosensory Cortex,NCP.NC.PG.S1]]
 VisualCortex=[[BrainCenterNC_LOBE_OCC|Occipital Lobe,NC.LOBE.OCC]]
<img src="http://ahuman.org/svn/ahwiki/images/ext/c42500e1552f1c4fb7efbead39db13a4.jpg" alt=alt="unavailable" style="max-width: 100%;">

* [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/emotional_top.jpg Prefrontal Cortex (PFC) in emotional behavior] - see [https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 Reference] (CF.PFC-EMOTIONS)

 ACG=Anterior Cingulate Cortex,NC.AL.ACG (see [[BrainCenterNC_ACG|Anterior Cingulate Area]])
 AM=[[BrainCenterFAM_FT_AM|Amygdala,FAM.FT.AM]]
 HCA=Hippocampus,FMM.FT.HC (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]])
 HT=[[BrainCenterFD_HT|Hypothalamus,FD.HT]]
 LPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see [[BrainCenterNC_AL_LPFC|Lateral Prefrontal Cortex]])
 OPFC=Orbitofrontal Cortex,NC.AL.OPFC (see [[BrainCenterNC_AL_OMPFC|Orbitomedial Prefrontal Cortex]])
 PCA=[[BrainCenterNC_MPL|Medial Parietal Lobule,NC.MPL]]
 PN=Pontine Nuclear Complex,HT.PN (see [[BrainCenterHT_SN|Metencephalic Sensory Nuclei]])
 TH=Mediodorsal Nucleus of Thalamus,FD.TH.MD (see [[BrainCenterFD_TH_CR|Cognitive Thalamus]])
<img src="http://ahuman.org/svn/ahwiki/images/ext/7d91d7629de1c1676ca328be6b84f80c.jpg" alt=alt="unavailable" style="max-width: 100%;">

* [http://www.nature.com/nrn/journal/v5/n7/images/nrn1432-f2.jpg Feeling] - see [http://www.nature.com/nrn/journal/v5/n7 Reference] (CF.FEELING)

 AN=Anterior Nucleus of Thalamus,FD.TH.AN (see [[BrainCenterFD_TH_CR|Cognitive Thalamus]])
 CG=[[BrainRegionNCP_NC_MPL_PSCG|Posterior Cingulate Cortex,NCP.NC.MPL.PSCG]]
 HC=Hippocampus,FMM.FT.HC (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]])
 HT=[[BrainCenterFD_HT|Hypothalamus,FD.HT]]
<img src="http://ahuman.org/svn/ahwiki/images/ext/739bae9479f0b9abd97f4fa36e001aff.jpg" alt=alt="unavailable" style="max-width: 100%;">

* [http://www.frontiersin.org/files/Articles/1854/fncom-05-00001-HTML/image_m/fncom-05-00001-g006.jpg Gating of medial prefrontal activity by the entorhinal cortex] - see [http://journal.frontiersin.org/article/10.3389/fncom.2011.00001/full Reference] (CF.EC-MPFC)

 EC=Entorhinal Cortex,FMM.NC.PH.ET (see [[BrainCenterNC_PHA_RH|Rhinal Cortex]])
 HC=Hippocampus,FMM.FT.HC (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]])
 MPFC=Medial Prefrontal Cortex,NC.AL.MPFC (see [[BrainCenterNC_AL_OMPFC|Orbitomedial Prefrontal Cortex]])
<img src="http://ahuman.org/svn/ahwiki/images/ext/a5a2fdaa7255e8a7c7262baa9b528b90.jpg" alt=alt="unavailable" style="max-width: 100%;">

* [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/am/hippocampo-amygdala-projections.png Detailed amygdalohippocampal projections] - see [https://books.google.ru/books?id=P3fSBwAAQBAJ Reference] (CF.AM-HC-DET)

 ABmg=[[BrainRegionFAM_FT_AM_AB|Accessory Basal Amygdaloid Nucleus,FAM.FT.AM.AB]]
 Bmg=[[BrainRegionFAM_FT_AM_BM|Magnocellular Basal Amygdaloid Nucleus,FAM.FT.AM.BM]]
 Bpc=[[BrainRegionFAM_FT_AM_BP|Parvicellular Basal Amygdaloid Nucleus,FAM.FT.AM.BP]]
 CA1D=[[BrainRegionFMM_FT_HC_CA1D|Distal CA1 of Hippocampus,FMM.FT.HC.CA1D]]
 CA1P=[[BrainRegionFMM_FT_HC_CA1P|Proximal CA1 of Hippocampus,FMM.FT.HC.CA1P]]
 L=Lateral Amygdaloid Nucleus,FAM.FT.AM.LA (see [[BrainCenterFAM_FT_AM|Amygdala]])
 PaS=[[BrainRegionFMM_NC_PH_PAS|Parasubiculum,FMM.NC.PH.PAS]]
 PrS=[[BrainRegionFMM_NC_PH_PRS|Presubiculum,FMM.NC.PH.PRS]]
<img src="http://ahuman.org/svn/ahwiki/images/ext/3121df9834588ca3e60638859e5381a2.png" alt=alt="unavailable" style="max-width: 100%;">


= References =
(generated)

* http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F4.html
* http://www.scholarpedia.org/article/Head_direction_cells
* http://www.sciencedirect.com/science/article/pii/S0149763411001722
* http://learnmem.cshlp.org/content/14/11/714/F1.expansion
* http://www.nature.com/nrn/journal/v3/n2/fig_tab/nrn726_F3.html
* https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988
* http://www.nature.com/nrn/journal/v5/n7
* http://journal.frontiersin.org/article/10.3389/fncom.2011.00001/full
* https://books.google.ru/books?id=P3fSBwAAQBAJ