#summary Ventromedial Prefrontal Cortex
@@[Home] -> [BiologicalLifeResearch] -> [BrainAreaNDM] -> [BrainRegionNDM_NC_AL_VMPFC]
----

This page covers biological details of component Ventromedial Prefrontal Cortex.
Region is part of aHuman target integrated biological model.

  * *Top-down path to region*: Cerebral Cortex -> Anterior Lobe (NC.LOBE.ANT) -> Prefrontal Cortex (NC.AL.PFC) -> [BrainCenterNC_AL_OMPFC Orbitomedial Prefrontal Cortex] (NC.AL.OMPFC) -> Medial Prefrontal Cortex (NC.AL.MPFC) -> [BrainRegionNDM_NC_AL_VMPFC Ventromedial Prefrontal Cortex] (NDM.NC.AL.VMPFC) (see [OverallMindMaps Mind Maps])
  * *Type*: cortex
  * *Quality*: L0
  * *Brain area*: [BrainAreaNDM Neocortical Brain - Decision Making Area] (NDM)
  * *Area circuit*: Motivatory Associations (MAS)
  * *Brodmann ID*: 11
  * *Role*: cortex.generic
  * *Function*: Ongoing Introverted Attention with Regard to Emotions and Feelings, Reward or Punishment
  * *Notes to function*: 
   * lower MPFC, primary connections to limbic and sensory cortices
   *  Reward mediated behaviours
(generated)
= Components =
(generated)


  * no child items defined

= Connectivity =
(generated)


http://ahuman.org/svn/ahwiki/images/dot/NDM.NC.AL.VMPFC.dot.png

*Inbound Region Connections:*

|| *Source Area* || *Source Region* || *Source Name* || *Type* || *Role* || *Reference* ||
|| [BrainAreaFAM FAM] || [BrainRegionFAM_FT_SEP_DBB FAM.FT.SEP.DBB] || Diagonal Band of Broca || inhibitory-gaba || uncertain ||(unknown reference) ||
|| [BrainAreaFMM FMM] || [BrainRegionFMM_FT_HC_CA1D FMM.FT.HC.CA1D] || Distal CA1 of Hippocampus || excitatory-glu || uncertain ||[http://journal.frontiersin.org/article/10.3389/fncom.2011.00001/full Gating of medial prefrontal activity by the entorhinal cortex (HC -> MPFC, abstract)] ||
|| [BrainAreaNDM NDM] || [BrainRegionNDM_FD_TH_PV NDM.FD.TH.PV] || Paraventricular Nucleus of Thalamus || excitatory-glu || uncertain ||[http://www.nature.com/nrn/journal/v5/n3/box/nrn1345_BX1.html Saccadic Vision (Thalamus -> FrontalCortex, abstract)] ||
||  || [BrainRegionNDM_NC_AL_DLPFCR NDM.NC.AL.DLPFCR] || Rostral Mid-Dorsolateral Prefrontal Cortex || feedforward-glu || uncertain ||[https://brmlab.cz/project/brain_hacking/tdcs/pfc Fear regulation (dlPFC -> vmPFC, abstract)] ||

*Outbound Region Connections:*

|| *Target Area* || *Target Region* || *Target Name* || *Type* || *Role* || *Reference* ||
|| [BrainAreaFAM FAM] || [BrainRegionFAM_FT_AM_ITC FAM.FT.AM.ITC] || Intercalated Amygdaloid Nuclei || excitatory-glu || uncertain || (unknown reference) ||
||  || [BrainRegionFAM_FT_AM_LADL FAM.FT.AM.LADL] || Dorsolateral Amygdaloid Nucleus || excitatory-glu || uncertain || (unknown reference) ||

= Thirdparty Circuits =
(generated)

  * [http://www.nature.com/npp/journal/v35/n1/images/npp2009121f1.jpg Fear regulation] - see [https://brmlab.cz/project/brain_hacking/tdcs/pfc Reference] (CF.FEAR-REG)

 B=Basal Amygdaloid Nucleus,FAM.FT.AM.B (see [BrainCenterFAM_FT_AM Amygdala])
 CE=Central Amygdala,FAM.FT.AM.CEA (see [BrainCenterFAM_FT_AM Amygdala])
 Hippocampus=Hippocampus,FMM.FT.HC (see [BrainCenterFMM_FT_HF Hippocampal Formation])
 Hypothalamus=[BrainCenterFD_HT Hypothalamus,FD.HT]
 ITC=[BrainRegionFAM_FT_AM_ITC Intercalated Amygdaloid Nuclei,FAM.FT.AM.ITC]
 LA=Lateral Amygdaloid Nucleus,FAM.FT.AM.LA (see [BrainCenterFAM_FT_AM Amygdala])
 Striatum=Striatum,FEC.FT.ST (see [BrainCenterFEC_FT_BG Basal Ganglia])
 dlPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see [BrainCenterNC_AL_LPFC Lateral Prefrontal Cortex])
 vmPFC=[BrainRegionNDM_NC_AL_VMPFC Ventromedial Prefrontal Cortex,NDM.NC.AL.VMPFC]
<img src="http://www.nature.com/npp/journal/v35/n1/images/npp2009121f1.jpg" alt="unavailable" style="max-width: 100%;">


= References =
(generated)

  * https://brmlab.cz/project/brain_hacking/tdcs/pfc