#summary Most Rostral Orbitofrontal Cortex @@[Home] -> [BiologicalLifeResearch] -> [BrainAreaNDM] -> [BrainRegionNDM_NC_AL_ROFCR] ---- This page covers biological details of component Most Rostral Orbitofrontal Cortex. Region is part of aHuman target integrated biological model. * *Top-down path to region*: Cerebral Cortex -> Anterior Lobe (NC.LOBE.ANT) -> Prefrontal Cortex (NC.AL.PFC) -> [BrainCenterNC_AL_OMPFC Orbitomedial Prefrontal Cortex] (NC.AL.OMPFC) -> Orbitofrontal Cortex (NC.AL.OPFC) -> Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFC) -> [BrainRegionNDM_NC_AL_ROFCR Most Rostral Orbitofrontal Cortex] (NDM.NC.AL.ROFCR) (see [OverallMindMaps Mind Maps]) * *Type*: cortex * *Quality*: L0 * *Brain area*: [BrainAreaNDM Neocortical Brain - Decision Making Area] (NDM) * *Area circuit*: High-Level Novelty Attention (HLNM) * *Brodmann ID*: 12 * *Role*: cortex.generic * *Function*: Integral conscious selection of novelty * *Notes to function*: * 12R (generated) = Components = (generated) * no child items defined = Connectivity = (generated) http://ahuman.org/svn/ahwiki/images/dot/NDM.NC.AL.ROFCR.dot.png *Inbound Region Connections:* || *Source Area* || *Source Region* || *Source Name* || *Type* || *Role* || *Reference* || || [BrainAreaFAM FAM] || [BrainRegionFAM_FD_TH_PT FAM.FD.TH.PT] || Paratenial Nucleus of Thalamus || excitatory-glu || uncertain ||[http://www.nature.com/nrn/journal/v5/n3/box/nrn1345_BX1.html Saccadic Vision (Thalamus -> FrontalCortex, abstract)] || || [BrainAreaFMM FMM] || [BrainRegionFMM_FT_HC_CA1D FMM.FT.HC.CA1D] || Distal CA1 of Hippocampus || excitatory-glu || uncertain ||[http://www.sciencedirect.com/science/article/pii/S030100820900183X Simplified model of hippocampal formation anatomy (CA1 -> mPFC, abstract)] || || || [BrainRegionFMM_FT_HF_SUBD FMM.FT.HF.SUBD] || Distal Subiculum || excitatory-glu || uncertain ||[http://www.sciencedirect.com/science/article/pii/S030100820900183X Simplified model of hippocampal formation anatomy (SUB -> mPFC, abstract)] || || [BrainAreaNCP NCP] || [BrainRegionNCP_NC_MPL_RSC NCP.NC.MPL.RSC] || Retrosplenial Cortex || feedforward-glu || uncertain ||[https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 Prefrontal Cortex (PFC) in emotional behavior (PCA -> OPFC, abstract)] || || [BrainAreaNDM NDM] || [BrainRegionNDM_NC_AL_ROFCL NDM.NC.AL.ROFCL] || Lateral Rostral Orbitofrontal Cortex || feedforward-glu || uncertain ||[http://brmlab.cz/project/brain_hacking/tdcs/pfc Regulation of Social Brain (MPFC -> OFC, abstract)] || || || [BrainRegionNDM_NC_AL_ROFCM NDM.NC.AL.ROFCM] || Medial Rostral Orbitofrontal Cortex || feedforward-glu || uncertain ||[http://brmlab.cz/project/brain_hacking/tdcs/pfc Regulation of Social Brain (MPFC -> OFC, abstract)] || *Outbound Region Connections:* || *Target Area* || *Target Region* || *Target Name* || *Type* || *Role* || *Reference* || || [BrainAreaFEC FEC] || [BrainRegionFEC_FD_STN_DL FEC.FD.STN.DL] || Subthalamic Nucleus Dorsolateral || excitatory-glu || uncertain || [http://www.degruyter.com/view/j/revneuro.2014.25.issue-4/revneuro-2014-0004/revneuro-2014-0004.xml Serotonin regulation of subthalamic neurons (CTX -> STN, abstract)] || || || [BrainRegionFEC_FT_CN_TL FEC.FT.CN.TL] || Caudate Nucleus Tail || excitatory-glu || uncertain || [http://www.sciencedirect.com/science/article/pii/S0959438808001566 Global visual system (FrontalCortex -> BGA, abstract)] || || [BrainAreaFMM FMM] || [BrainRegionFMM_FD_TH_RE FMM.FD.TH.RE] || Reuniens Nucleus of Thalamus || excitatory-glu || uncertain || (unknown reference) || || || [BrainRegionFMM_FD_TH_RH FMM.FD.TH.RH] || Rhomboidal Nucleus of Thalamus || excitatory-glu || uncertain || (unknown reference) || || [BrainAreaNDM NDM] || [BrainRegionNDM_NC_AL_DACG NDM.NC.AL.DACG] || Dorsal Anterior Cingulate Area || feedforward-glu || uncertain || [http://www.pnas.org/content/107/40/17071/F1.expansion.html Role for serotonin in moral behavior (OMPFC -> ACG, abstract)] || || || [BrainRegionNDM_NC_AL_IPG NDM.NC.AL.IPG] || Inferior Prefrontal Gyrus || feedforward-glu || uncertain || [http://brmlab.cz/project/brain_hacking/tdcs/pfc Regulation of Social Brain (OFC -> IFG, abstract)] || = Thirdparty Circuits = (generated) * [http://brmlab.cz/lib/exe/fetch.php?hash=fca48f&media=http%3A%2F%2Fars.els-cdn.com%2Fcontent%2Fimage%2F1-s2.0-S1364661308002490-gr2.jpg Regulation of Social Brain] - see [http://brmlab.cz/project/brain_hacking/tdcs/pfc Reference] (CT.SOCIAL-BRAIN) AMG=[BrainCenterFAM_FT_AM Amygdala,FAM.FT.AM] Caud=Caudate Nucleus,FEC.FT.CN (see [BrainCenterFEC_FT_BG Basal Ganglia]) DACC=[BrainRegionNDM_NC_AL_DACG Dorsal Anterior Cingulate Area,NDM.NC.AL.DACG] DLPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see [BrainCenterNC_AL_LPFC Lateral Prefrontal Cortex]) Hipp=Hippocampus,FMM.FT.HC (see [BrainCenterFMM_FT_HF Hippocampal Formation]) IFG=[BrainRegionNDM_NC_AL_IPG Inferior Prefrontal Gyrus,NDM.NC.AL.IPG] LSN=[BrainRegionLAC_SC_LH_LSN Lateral Spinal Nucleus,LAC.SC.LH.LSN] MPFC=Orbitofrontal Cortex,NC.AL.OPFC (see [BrainCenterNC_AL_OMPFC Orbitomedial Prefrontal Cortex]) NACC=Accumbens Nucleus,FEC.FT.ACC (see [BrainCenterFEC_FT_BG Basal Ganglia]) OFC=Orbitofrontal Cortex,NC.AL.OPFC (see [BrainCenterNC_AL_OMPFC Orbitomedial Prefrontal Cortex]) PhippG=Entorhinal Cortex,FMM.NC.PH.ET (see [BrainCenterNC_PHA_RH Rhinal Cortex]) Put=Dorsal Putamen,FEC.FT.DPU (see [BrainCenterFEC_FT_BG Basal Ganglia]) SGC=[BrainRegionNCP_NC_AL_SGCG Subgenual Cingulate Cortex,NCP.NC.AL.SGCG] SN=Substantia Nigra,FEC.FT.SN (see [BrainCenterFEC_FT_BG Basal Ganglia]) VACC=[BrainRegionNDM_NC_AL_VACG Ventral Anterior Cingulate Area,NDM.NC.AL.VACG] VTA=[BrainRegionLMC_MM_VTA Ventral Tegmental Area,LMC.MM.VTA] VentPal=Ventral Pallidum,FEC.FT.VP (see [BrainCenterFEC_FT_BG Basal Ganglia]) unavailable * [http://ars.els-cdn.com/content/image/1-s2.0-S0959438808001566-gr1.jpg Global visual system] - see [http://www.sciencedirect.com/science/article/pii/S0959438808001566 Reference] (CP.GLOBAL-VISUAL-SYSTEM) ATH=Anterior Nucleus of Thalamus,FD.TH.AN (see [BrainCenterFD_TH_CR Cognitive Thalamus]) BGA=[BrainCenterFEC_FT_BG Basal Ganglia,FEC.FT.BG] FrontalCortex=Anterior Lobe,NC.LOBE.ANT LGN=[BrainRegionNSA_FD_LGN Lateral Geniculate Nucleus,NSA.FD.LGN] OPN=[BrainRegionLPC_MM_OCN Oculomotor Nucleus,LPC.MM.OCN] ParietalCortex=Parietal Lobe,NC.LOBE.PAR Pulvinar=Pulvinar,FD.PV (see [BrainCenterFD_TH_SR Sensory Thalamus]) RF=[BrainCenterHT_RF Pontine Reticular Formation,HT.RF] Retina=[BrainRegionLPC_FD_RT Retinal Nucleus,LPC.FD.RT] SCi=Superior Colliculus,MM.SC (see [BrainCenterMM_REF Reflexes Nuclei of Midbrain Mesencephalon]) SCs=Superior Colliculus,MM.SC (see [BrainCenterMM_REF Reflexes Nuclei of Midbrain Mesencephalon]) SNc=[BrainRegionFEC_FT_SNC_LT Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT] SNr=[BrainRegionFEC_FT_SNR_DL Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL] SpinalCord=Lamina IX,SC.VH.L9 (see [BrainCenterSC_VH Anterior/Ventral Horn]) Striatum=Striatum,FEC.FT.ST (see [BrainCenterFEC_FT_BG Basal Ganglia]) VisualCortex=[BrainCenterNC_LOBE_OCC Occipital Lobe,NC.LOBE.OCC] unavailable * [http://www.degruyter.com/view/j/revneuro.2014.25.issue-4/revneuro-2014-0004/graphic/revneuro-2014-0004_fig1.jpg Serotonin regulation of subthalamic neurons] - see [http://www.degruyter.com/view/j/revneuro.2014.25.issue-4/revneuro-2014-0004/revneuro-2014-0004.xml Reference] (CM.SUBTHALAMUS) CTX=Anterior Lobe,NC.LOBE.ANT GPe=Globus Pallidus External,FEC.FT.GPE (see [BrainCenterFEC_FT_BG Basal Ganglia]) GPi=Globus Pallidus Internal,FEC.FT.GPI (see [BrainCenterFEC_FT_BG Basal Ganglia]) PPN=[BrainRegionLMC_HT_TG_PPN Pedunculopontine Tegmental Nuclei,LMC.HT.TG.PPN] SNr=Substantia Nigra Pars Reticulata,FEC.FT.SNR (see [BrainCenterFEC_FT_BG Basal Ganglia]) STN=Subthalamic Nucleus,FEC.FD.STN (see [BrainCenterFEC_FD_STA Subthalamus Area]) unavailable * [http://www.pnas.org/content/107/40/17071/F1.medium.gif Role for serotonin in moral behavior] - see [http://www.pnas.org/content/107/40/17071/F1.expansion.html Reference] (CF.EMOTIONAL-MODULATION) ACG=Anterior Cingulate Cortex,NC.AL.ACG (see [BrainCenterNC_ACG Anterior Cingulate Area]) AMY=[BrainCenterFAM_FT_AM Amygdala,FAM.FT.AM] HYP=[BrainCenterFD_HT Hypothalamus,FD.HT] LPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see [BrainCenterNC_AL_LPFC Lateral Prefrontal Cortex]) OMPFC=Orbitofrontal Cortex,NC.AL.OPFC (see [BrainCenterNC_AL_OMPFC Orbitomedial Prefrontal Cortex]) unavailable = References = (generated) * http://brmlab.cz/project/brain_hacking/tdcs/pfc * http://www.sciencedirect.com/science/article/pii/S0959438808001566 * http://www.degruyter.com/view/j/revneuro.2014.25.issue-4/revneuro-2014-0004/revneuro-2014-0004.xml * http://www.pnas.org/content/107/40/17071/F1.expansion.html