#summary Rostral Mid-Dorsolateral Prefrontal Cortex @@[Home] -> [BiologicalLifeResearch] -> [BrainAreaNDM] -> [BrainRegionNDM_NC_AL_DLPFCR] ---- This page covers biological details of component Rostral Mid-Dorsolateral Prefrontal Cortex. Region is part of aHuman target integrated biological model. * *Top-down path to region*: Cerebral Cortex -> Anterior Lobe (NC.LOBE.ANT) -> Prefrontal Cortex (NC.AL.PFC) -> [BrainCenterNC_AL_LPFC Lateral Prefrontal Cortex] (NC.AL.LPFC) -> Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFC) -> [BrainRegionNDM_NC_AL_DLPFCR Rostral Mid-Dorsolateral Prefrontal Cortex] (NDM.NC.AL.DLPFCR) (see [OverallMindMaps Mind Maps]) * *Type*: cortex * *Quality*: L0 * *Brain area*: [BrainAreaNDM Neocortical Brain - Decision Making Area] (NDM) * *Area circuit*: Working Memory (HWM) * *Brodmann ID*: 46 * *Role*: cortex.generic * *Function*: Cognitive control and monitoring to resolve conflict in information processing and competing response plans (generated) = Components = (generated) * no child items defined = Connectivity = (generated) http://ahuman.org/svn/ahwiki/images/dot/NDM.NC.AL.DLPFCR.dot.png *Inbound Region Connections:* || *Source Area* || *Source Region* || *Source Name* || *Type* || *Role* || *Reference* || || [BrainAreaNCP NCP] || [BrainRegionNCP_NC_MPL_RSC NCP.NC.MPL.RSC] || Retrosplenial Cortex || feedforward-glu || uncertain ||[https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 Prefrontal Cortex (PFC) in emotional behavior (PCA -> LPFC, abstract)] || || [BrainAreaNDM NDM] || [BrainRegionNDM_FD_TH_MDM NDM.FD.TH.MDM] || Medial Mediodorsal Nucleus of Thalamus || excitatory-glu || uncertain ||[https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 Prefrontal Cortex (PFC) in emotional behavior (TH -> LPFC, abstract)] || || || [BrainRegionNDM_NC_AL_FPC NDM.NC.AL.FPC] || Lateral Frontopolar Cortex || feedforward-glu || uncertain ||[https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 Prefrontal Cortex (PFC) in emotional behavior (OPFC -> LPFC, abstract)] || || || [BrainRegionNDM_NC_AL_VACG NDM.NC.AL.VACG] || Ventral Anterior Cingulate Area || feedforward-glu || uncertain ||[http://www.pnas.org/content/107/40/17071/F1.expansion.html Role for serotonin in moral behavior (ACG -> LPFC, abstract)] || || [BrainAreaNPE NPE] || [BrainRegionNPE_NC_IPL_MST NPE.NC.IPL.MST] || Medial Superior Temporal Area || feedforward-glu || uncertain ||[http://www.sciencedirect.com/science/article/pii/S1053810011000080 Cortico-Cortical Connectivity (PTHA -> PFC, abstract)] || || || [BrainRegionNPE_NC_IPS_LIP NPE.NC.IPS.LIP] || Lateral Intraparietal Sulcus || feedforward-glu || uncertain ||[http://www.cixip.com/index.php/page/content/id/1190 Summary of eye movement control (PEF -> DLPFC, abstract)] || *Outbound Region Connections:* || *Target Area* || *Target Region* || *Target Name* || *Type* || *Role* || *Reference* || || [BrainAreaNDM NDM] || [BrainRegionNDM_NC_AL_DACG NDM.NC.AL.DACG] || Dorsal Anterior Cingulate Area || feedforward-glu || uncertain || [https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 Prefrontal Cortex (PFC) in emotional behavior (LPFC -> ACG, abstract)] || || || [BrainRegionNDM_NC_AL_VMPFC NDM.NC.AL.VMPFC] || Ventromedial Prefrontal Cortex || feedforward-glu || uncertain || [https://brmlab.cz/project/brain_hacking/tdcs/pfc Fear regulation (dlPFC -> vmPFC, abstract)] || || [BrainAreaNMA NMA] || [BrainRegionNMA_NC_PMC_F7 NMA.NC.PMC.F7] || Dorsal Rostral Premotor Cortex || feedforward-glu || uncertain || [https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 Prefrontal Cortex (PFC) in motor behavior (LPFC -> PMC, abstract)] || || || [BrainRegionNMA_NC_SMC_F6 NMA.NC.SMC.F6] || Pre-Supplementary Motor Area || feedforward-glu || uncertain || [http://www.sciencedirect.com/science/article/pii/S0893608098000471 Primate Control of Grasping (46 -> F6, abstract)] || || [BrainAreaNPE NPE] || [BrainRegionNPE_NC_SMC_SEF NPE.NC.SMC.SEF] || Supplementary Eye Field || feedforward-glu || uncertain || [http://ahuman.org/svn/ahengine/research/articles/Biological/2008-dorsal-stream.pdf 3 Visual Cortex Paths (LPC -> pre-SMA, abstract)] || = Thirdparty Circuits = (generated) * [http://ars.els-cdn.com/content/image/1-s2.0-S0959438808001566-gr1.jpg Global visual system] - see [http://www.sciencedirect.com/science/article/pii/S0959438808001566 Reference] (CP.GLOBAL-VISUAL-SYSTEM) ATH=Anterior Nucleus of Thalamus,FD.TH.AN (see [BrainCenterFD_TH_CR Cognitive Thalamus]) BGA=[BrainCenterFEC_FT_BG Basal Ganglia,FEC.FT.BG] FrontalCortex=Anterior Lobe,NC.LOBE.ANT LGN=[BrainRegionNSA_FD_LGN Lateral Geniculate Nucleus,NSA.FD.LGN] OPN=[BrainRegionLPC_MM_OCN Oculomotor Nucleus,LPC.MM.OCN] ParietalCortex=Parietal Lobe,NC.LOBE.PAR Pulvinar=Pulvinar,FD.PV (see [BrainCenterFD_TH_SR Sensory Thalamus]) RF=[BrainCenterHT_RF Pontine Reticular Formation,HT.RF] Retina=[BrainRegionLPC_FD_RT Retinal Nucleus,LPC.FD.RT] SCi=Superior Colliculus,MM.SC (see [BrainCenterMM_REF Reflexes Nuclei of Midbrain Mesencephalon]) SCs=Superior Colliculus,MM.SC (see [BrainCenterMM_REF Reflexes Nuclei of Midbrain Mesencephalon]) SNc=[BrainRegionFEC_FT_SNC_LT Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT] SNr=[BrainRegionFEC_FT_SNR_DL Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL] SpinalCord=Lamina IX,SC.VH.L9 (see [BrainCenterSC_VH Anterior/Ventral Horn]) Striatum=Striatum,FEC.FT.ST (see [BrainCenterFEC_FT_BG Basal Ganglia]) VisualCortex=[BrainCenterNC_LOBE_OCC Occipital Lobe,NC.LOBE.OCC] unavailable * [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/visual-streams.jpg 3 Visual Cortex Paths] - see [article:Biological/2008-dorsal-stream.pdf Reference] (CP.BASE-VISUAL-CORTEX-FLOWS) IPL=[BrainCenterNC_IPL Inferior Parietal Lobule,NC.IPL] IPS=[BrainCenterNSA_NC_IPS Intraparietal Sulcus,NSA.NC.IPS] IT=[BrainCenterNSA_NC_IT Inferotemporal Area,NSA.NC.IT] LPC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see [BrainCenterNC_AL_LPFC Lateral Prefrontal Cortex]) MI=[BrainRegionNMA_NC_MC Motor Cortex,NMA.NC.MC] OCC=[BrainCenterNC_LOBE_OCC Occipital Lobe,NC.LOBE.OCC] SPL=[BrainCenterNC_SPL Superior Parietal Lobule,NC.SPL] dPM=Dorsal Premotor Cortex,MCA.NC.DPMC (see [BrainCenterNC_PMC Premotor Cortex]) pre-SMA=[BrainCenterNMA_NC_SMC Supplementary Motor Cortex,NMA.NC.SMC] vPM=Ventral Premotor Cortex,MCA.NC.VPMC (see [BrainCenterNC_PMC Premotor Cortex]) unavailable * [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/motor_top.jpg Prefrontal Cortex (PFC) in motor behavior] - see [https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 Reference] (CM.PFC-MOTOR) CN.PU=Striatum,FEC.FT.ST (see [BrainCenterFEC_FT_BG Basal Ganglia]) CR=[BrainCenterLLC_HT_CRC Cerebellar Complex,LLC.HT.CRC] GP=Globus Pallidus,FEC.FT.GP (see [BrainCenterFEC_FT_BG Basal Ganglia]) LPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see [BrainCenterNC_AL_LPFC Lateral Prefrontal Cortex]) MC=[BrainRegionNMA_NC_MC Motor Cortex,NMA.NC.MC] PMC=[BrainCenterNC_PMC Premotor Cortex,NC.PMC] PN=Pontine Nuclear Complex,HT.PN (see [BrainCenterHT_SN Metencephalic Sensory Nuclei]) SN=Substantia Nigra,FEC.FT.SN (see [BrainCenterFEC_FT_BG Basal Ganglia]) TH=Ventral Thalamus,FD.TH.VTH (see [BrainCenterFD_TH_MR Motor Thalamus]) unavailable * [http://ars.els-cdn.com/content/image/1-s2.0-S0893608098000471-gr6.gif Primate Control of Grasping] - see [http://www.sciencedirect.com/science/article/pii/S0893608098000471 Reference] (CM.GRASPING-CONTROL) 46=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see [BrainCenterNC_AL_LPFC Lateral Prefrontal Cortex]) AIP=[BrainRegionNSA_NC_IPS_AIP Anterior Intraparietal Sulcus,NSA.NC.IPS.AIP] BG=[BrainCenterFEC_FT_BG Basal Ganglia,FEC.FT.BG] BTH=[BrainRegionNMA_FD_TH_VA Ventral Anterior Nucleus,NMA.FD.TH.VA] F1=[BrainRegionNMA_NC_MC Motor Cortex,NMA.NC.MC] F2=[BrainRegionNMA_NC_PMC_F2 Dorsal Caudal Premotor Cortex,NMA.NC.PMC.F2] F4=[BrainRegionNMA_NC_PMC_F4 Ventral Caudal Premotor Cortex,NMA.NC.PMC.F4] F5=[BrainRegionNMA_NC_PMC_F5 Ventral Rostral Premotor Cortex,NMA.NC.PMC.F5] F6=[BrainRegionNMA_NC_SMC_F6 Pre-Supplementary Motor Area,NMA.NC.SMC.F6] IT=[BrainCenterNSA_NC_IT Inferotemporal Area,NSA.NC.IT] PIP=Posterior Eye Field,NPE.NC.IPS.PEF (see [BrainCenterNSA_NC_IPS Intraparietal Sulcus]) S1=[BrainRegionNCP_NC_PG_S1 Primary Somatosensory Cortex,NCP.NC.PG.S1] S2=[BrainRegionNCP_NC_PG_S1 Primary Somatosensory Cortex,NCP.NC.PG.S1] VC=[BrainCenterNC_LOBE_OCC Occipital Lobe,NC.LOBE.OCC] VIP=[BrainRegionNSA_NC_IPS_VIP Ventral Intraparietal Sulcus,NSA.NC.IPS.VIP] unavailable * [http://what-when-how.com/wp-content/uploads/2012/04/tmp3649_thumb1_thumb.jpg Thalamocortical relationships] - see [http://what-when-how.com/neuroscience/the-thalamus-and-cerebral-cortex-integrative-systems-part-2/ Reference] (CL.THALAMUS-PROJECTIONS) A=Anterior Nucleus of Thalamus,FD.TH.AN (see [BrainCenterFD_TH_CR Cognitive Thalamus]) CM=[BrainRegionFEC_FD_TH_CM Centromedian Nucleus of Thalamus,FEC.FD.TH.CM] LD=[BrainRegionFMM_FD_TH_LD Lateral Dorsal Nucleus of Thalamus,FMM.FD.TH.LD] LGN=[BrainRegionNSA_FD_LGN Lateral Geniculate Nucleus,NSA.FD.LGN] LP=[BrainRegionNPE_FD_TH_LP Lateral Posterior Nucleus of Thalamus,NPE.FD.TH.LP] MD=Mediodorsal Nucleus of Thalamus,FD.TH.MD (see [BrainCenterFD_TH_CR Cognitive Thalamus]) MGN=[BrainRegionNSA_FD_TH_MGB Medial Geniculate Body,NSA.FD.TH.MGB] P=Ventral Posterior Nuclei,NSA.FD.TH.VP (see [BrainCenterFD_TH_SR Sensory Thalamus]) VA=[BrainRegionNMA_FD_TH_VA Ventral Anterior Nucleus,NMA.FD.TH.VA] VL=[BrainRegionNMA_FD_TH_VL Ventral Lateral Nucleus,NMA.FD.TH.VL] VPL=[BrainRegionNCP_FD_TH_VPL Ventral Posterolateral Nucleus,NCP.FD.TH.VPL] VPM=[BrainRegionNCP_FD_TH_VPM Ventral Posteromedial Nucleus,NCP.FD.TH.VPM] pA=[BrainRegionNCP_NC_MPL_PSCG Posterior Cingulate Cortex,NCP.NC.MPL.PSCG] pCM=Dorsal Putamen,FEC.FT.DPU (see [BrainCenterFEC_FT_BG Basal Ganglia]) pLD=Anterior Cingulate Cortex,NC.AL.ACG (see [BrainCenterNC_ACG Anterior Cingulate Area]) pLGN=[BrainRegionNSA_NC_OCC_V1 Primary Visual Cortex,NSA.NC.OCC.V1] pLP=[BrainCenterNC_SPL Superior Parietal Lobule,NC.SPL] pMD=Prefrontal Cortex,NC.AL.PFC pMGN=[BrainRegionNSA_NC_TTG_A1 Primary Auditory Cortex,NSA.NC.TTG.A1] pP=[BrainCenterNC_INS Insular Cortex,NC.INS] pVA=[BrainCenterNMA_NC_SMC Supplementary Motor Cortex,NMA.NC.SMC] pVL=[BrainRegionNMA_NC_MC Motor Cortex,NMA.NC.MC] pVPL=[BrainRegionNCP_NC_PG_S1 Primary Somatosensory Cortex,NCP.NC.PG.S1] pVPM=[BrainRegionNCP_NC_PO_PCC Precentral Cortex,NCP.NC.PO.PCC] s1A=Subiculum,FMM.FT.HF.SUB (see [BrainCenterFMM_FT_HF Hippocampal Formation]) s1MD=[BrainCenterFAM_FT_SEP Septal Nuclei,FAM.FT.SEP] s1P=[BrainRegionLPC_SC_IZ_CCV Central Cervical Nucleus,LPC.SC.IZ.CCV] s1VL=[BrainRegionLLC_HT_CR_DN Dentate Nucleus,LLC.HT.CR.DN] s2A=Mammillary Body,FD.MB (see [BrainCenterFD_HT Hypothalamus]) s2MD=[BrainRegionNSA_NC_PH_PIR Piriform Cortex,NSA.NC.PH.PIR] s2P=[BrainRegionLPC_HT_PN_PTR Principal Trigeminal Nucleus,LPC.HT.PN.PTR] s2VL=[BrainCenterFEC_FT_BG Basal Ganglia,FEC.FT.BG] s3MD=Prefrontal Cortex,NC.AL.PFC sCM=Globus Pallidus Internal,FEC.FT.GPI (see [BrainCenterFEC_FT_BG Basal Ganglia]) sLD=[BrainCenterNC_SPL Superior Parietal Lobule,NC.SPL] sLP=Superior Colliculus,MM.SC (see [BrainCenterMM_REF Reflexes Nuclei of Midbrain Mesencephalon]) sVA=[BrainCenterFEC_FT_BG Basal Ganglia,FEC.FT.BG] sVPL=Marginal Nucleus,LPC.SC.PH.MG (see [BrainCenterBMA_SC_PH Posterior/Dorsal Horn]) sVPM=[BrainRegionLPC_HL_SOL Solitary Nucleus,LPC.HL.SOL] unavailable * [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/emotional_top.jpg Prefrontal Cortex (PFC) in emotional behavior] - see [https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 Reference] (CF.PFC-EMOTIONS) ACG=Anterior Cingulate Cortex,NC.AL.ACG (see [BrainCenterNC_ACG Anterior Cingulate Area]) AM=[BrainCenterFAM_FT_AM Amygdala,FAM.FT.AM] HCA=Hippocampus,FMM.FT.HC (see [BrainCenterFMM_FT_HF Hippocampal Formation]) HT=[BrainCenterFD_HT Hypothalamus,FD.HT] LPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see [BrainCenterNC_AL_LPFC Lateral Prefrontal Cortex]) OPFC=Orbitofrontal Cortex,NC.AL.OPFC (see [BrainCenterNC_AL_OMPFC Orbitomedial Prefrontal Cortex]) PCA=[BrainCenterNC_MPL Medial Parietal Lobule,NC.MPL] PN=Pontine Nuclear Complex,HT.PN (see [BrainCenterHT_SN Metencephalic Sensory Nuclei]) TH=Mediodorsal Nucleus of Thalamus,FD.TH.MD (see [BrainCenterFD_TH_CR Cognitive Thalamus]) unavailable * [http://www.nature.com/npp/journal/v35/n1/images/npp2009121f1.jpg Fear regulation] - see [https://brmlab.cz/project/brain_hacking/tdcs/pfc Reference] (CF.FEAR-REG) B=Basal Amygdaloid Nucleus,FAM.FT.AM.B (see [BrainCenterFAM_FT_AM Amygdala]) CE=Central Amygdala,FAM.FT.AM.CEA (see [BrainCenterFAM_FT_AM Amygdala]) Hippocampus=Hippocampus,FMM.FT.HC (see [BrainCenterFMM_FT_HF Hippocampal Formation]) Hypothalamus=[BrainCenterFD_HT Hypothalamus,FD.HT] ITC=[BrainRegionFAM_FT_AM_ITC Intercalated Amygdaloid Nuclei,FAM.FT.AM.ITC] LA=Lateral Amygdaloid Nucleus,FAM.FT.AM.LA (see [BrainCenterFAM_FT_AM Amygdala]) Striatum=Striatum,FEC.FT.ST (see [BrainCenterFEC_FT_BG Basal Ganglia]) dlPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see [BrainCenterNC_AL_LPFC Lateral Prefrontal Cortex]) vmPFC=[BrainRegionNDM_NC_AL_VMPFC Ventromedial Prefrontal Cortex,NDM.NC.AL.VMPFC] unavailable * [http://www.pnas.org/content/107/40/17071/F1.medium.gif Role for serotonin in moral behavior] - see [http://www.pnas.org/content/107/40/17071/F1.expansion.html Reference] (CF.EMOTIONAL-MODULATION) ACG=Anterior Cingulate Cortex,NC.AL.ACG (see [BrainCenterNC_ACG Anterior Cingulate Area]) AMY=[BrainCenterFAM_FT_AM Amygdala,FAM.FT.AM] HYP=[BrainCenterFD_HT Hypothalamus,FD.HT] LPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see [BrainCenterNC_AL_LPFC Lateral Prefrontal Cortex]) OMPFC=Orbitofrontal Cortex,NC.AL.OPFC (see [BrainCenterNC_AL_OMPFC Orbitomedial Prefrontal Cortex]) unavailable = References = (generated) * http://www.sciencedirect.com/science/article/pii/S0959438808001566 * article:Biological/2008-dorsal-stream.pdf * https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 * http://www.sciencedirect.com/science/article/pii/S0893608098000471 * http://what-when-how.com/neuroscience/the-thalamus-and-cerebral-cortex-integrative-systems-part-2/ * https://brmlab.cz/project/brain_hacking/tdcs/pfc * http://www.pnas.org/content/107/40/17071/F1.expansion.html