#summary Medial Mediodorsal Nucleus of Thalamus @@[Home] -> [BiologicalLifeResearch] -> [BrainAreaNDM] -> [BrainRegionNDM_FD_TH_MDM] ---- This page covers biological details of component Medial Mediodorsal Nucleus of Thalamus. Region is part of aHuman target integrated biological model. * *Top-down path to region*: Forebrain Diencephalon -> Thalamus (FD.TH) -> [BrainCenterFD_TH_CR Cognitive Thalamus] (FD.TH.CR) -> Mediodorsal Nucleus of Thalamus (FD.TH.MD) -> [BrainRegionNDM_FD_TH_MDM Medial Mediodorsal Nucleus of Thalamus] (NDM.FD.TH.MDM) (see [OverallMindMaps Mind Maps]) * *Type*: nucleus * *Quality*: L0 * *Brain area*: [BrainAreaNDM Neocortical Brain - Decision Making Area] (NDM) * *Area circuit*: High-Level Control (HLC) * *Role*: thalamic.cortex.reinforce * *Function*: relay emotional attention to orbitofrontal cortex * *Notes to function*: * orbitofrontal cortex (BA12,13) defined by MDm projection * relay AM-Bp to OFC * OFCm - subjective pleasantness, OFCl - subjective unpleasantness (generated) = Components = (generated) * no child items defined = Connectivity = (generated) http://ahuman.org/svn/ahwiki/images/dot/NDM.FD.TH.MDM.dot.png *Inbound Region Connections:* || *Source Area* || *Source Region* || *Source Name* || *Type* || *Role* || *Reference* || || [BrainAreaFAM FAM] || [BrainRegionFAM_FT_AM_AB FAM.FT.AM.AB] || Accessory Basal Amygdaloid Nucleus || excitatory-glu || uncertain ||[https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 Prefrontal Cortex (PFC) in emotional behavior (AM -> TH, abstract)] || || || [BrainRegionFAM_FT_AM_BP FAM.FT.AM.BP] || Parvicellular Basal Amygdaloid Nucleus || excitatory-glu || uncertain ||[http://www.surgicalneurologyint.com/article.asp?issn=2152-7806;year=2012;volume=3;issue=2;spage=40;epage=46;aulast=Langevin Amygdala and its network (BLN -> MD, abstract)] || || || [BrainRegionFAM_FT_SEP_MED FAM.FT.SEP.MED] || Medial Septal Nucleus || modulatory-ach || uncertain ||[http://what-when-how.com/neuroscience/the-thalamus-and-cerebral-cortex-integrative-systems-part-2/ Thalamocortical relationships (s1MD -> MD, abstract)] || || [BrainAreaFEC FEC] || [BrainRegionFEC_FT_GPI_RM FEC.FT.GPI.RM] || Globus Pallidus Internal Rostromedial || inhibitory-gaba || uncertain ||[http://www.nature.com/nrn/journal/v5/n3/box/nrn1345_BX1.html Saccadic Vision (BG -> Thalamus, abstract)] || || [BrainAreaFMM FMM] || [BrainRegionFMM_NC_PH_LEC FMM.NC.PH.LEC] || Lateral Entorhinal Cortex || excitatory-glu || uncertain ||[http://learnmem.cshlp.org/content/18/6/384/F1.expansion.html Contributions of Diencephalon to Recognition Memory (EC -> MDmc, abstract)] || || || [BrainRegionFMM_NC_PH_PER FMM.NC.PH.PER] || Perirhinal Cortex || excitatory-glu || uncertain ||[http://learnmem.cshlp.org/content/18/6/384/F1.expansion.html Contributions of Diencephalon to Recognition Memory (Perirhinal -> MDmc, abstract)] || || [BrainAreaNCP NCP] || [BrainRegionNCP_NC_MPL_PSCG NCP.NC.MPL.PSCG] || Posterior Cingulate Cortex || excitatory-glu || uncertain ||[http://learnmem.cshlp.org/content/18/6/384/F1.expansion.html Contributions of Diencephalon to Recognition Memory (PostCingulate -> MDmc, abstract)] || *Outbound Region Connections:* || *Target Area* || *Target Region* || *Target Name* || *Type* || *Role* || *Reference* || || [BrainAreaNDM NDM] || [BrainRegionNDM_NC_AL_DLPFCR NDM.NC.AL.DLPFCR] || Rostral Mid-Dorsolateral Prefrontal Cortex || excitatory-glu || uncertain || [https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 Prefrontal Cortex (PFC) in emotional behavior (TH -> LPFC, abstract)] || || || [BrainRegionNDM_NC_AL_FPC NDM.NC.AL.FPC] || Lateral Frontopolar Cortex || excitatory-glu || uncertain || [http://www.surgicalneurologyint.com/article.asp?issn=2152-7806;year=2012;volume=3;issue=2;spage=40;epage=46;aulast=Langevin Amygdala and its network (MD -> MPFC, abstract)] || = Thirdparty Circuits = (generated) * [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/emotional_top.jpg Prefrontal Cortex (PFC) in emotional behavior] - see [https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 Reference] (CF.PFC-EMOTIONS) ACG=Anterior Cingulate Cortex,NC.AL.ACG (see [BrainCenterNC_ACG Anterior Cingulate Area]) AM=[BrainCenterFAM_FT_AM Amygdala,FAM.FT.AM] HCA=Hippocampus,FMM.FT.HC (see [BrainCenterFMM_FT_HF Hippocampal Formation]) HT=[BrainCenterFD_HT Hypothalamus,FD.HT] LPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see [BrainCenterNC_AL_LPFC Lateral Prefrontal Cortex]) OPFC=Orbitofrontal Cortex,NC.AL.OPFC (see [BrainCenterNC_AL_OMPFC Orbitomedial Prefrontal Cortex]) PCA=[BrainCenterNC_MPL Medial Parietal Lobule,NC.MPL] PN=Pontine Nuclear Complex,HT.PN (see [BrainCenterHT_SN Metencephalic Sensory Nuclei]) TH=Mediodorsal Nucleus of Thalamus,FD.TH.MD (see [BrainCenterFD_TH_CR Cognitive Thalamus]) unavailable * [http://sni.wpengine.com/wp-content/uploads/2015/05/3520/SNI-3-40-g001.png Amygdala and its network] - see [http://www.surgicalneurologyint.com/article.asp?issn=2152-7806;year=2012;volume=3;issue=2;spage=40;epage=46;aulast=Langevin Reference] (CF.AM-NET) BLN=[BrainRegionFAM_FT_AM_BP Parvicellular Basal Amygdaloid Nucleus,FAM.FT.AM.BP] CEA=Central Amygdala,FAM.FT.AM.CEA (see [BrainCenterFAM_FT_AM Amygdala]) EC=Entorhinal Cortex,FMM.NC.PH.ET (see [BrainCenterNC_PHA_RH Rhinal Cortex]) HC=Hippocampus,FMM.FT.HC (see [BrainCenterFMM_FT_HF Hippocampal Formation]) HTS=[BrainRegionLAC_FD_HT_LTN Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN] ITC=[BrainRegionNSA_NC_IT_TE Inferotemporal Cortex,NSA.NC.IT.TE] LA=Lateral Amygdaloid Nucleus,FAM.FT.AM.LA (see [BrainCenterFAM_FT_AM Amygdala]) LHB=Lateral Habenula,FAM.FD.LHB (see [BrainCenterFAM_FD_HB Habenula]) MD=Mediodorsal Nucleus of Thalamus,FD.TH.MD (see [BrainCenterFD_TH_CR Cognitive Thalamus]) MPFC=[BrainCenterNC_AL_OMPFC Orbitomedial Prefrontal Cortex,NC.AL.OMPFC] NACC=Accumbens Nucleus,FEC.FT.ACC (see [BrainCenterFEC_FT_BG Basal Ganglia]) PAG=[BrainRegionLMC_MM_PAG Periaqueductal Gray Matter,LMC.MM.PAG] RMTG=[BrainRegionFEC_HT_TG_RMTG Rostromedial Tegmental Nucleus,FEC.HT.TG.RMTG] STC=[BrainRegionNSA_NC_STG_A3 Wernicke's area A3,NSA.NC.STG.A3] VGDM=[BrainRegionLAC_HL_VGN Vagus Nucleus,LAC.HL.VGN] VTA=[BrainRegionLMC_MM_VTA Ventral Tegmental Area,LMC.MM.VTA] unavailable * [http://neuropolitics.org/connect-amygdala.jpg Amygdalar disruption of prefrontal cortex] - see [http://neuropolitics.org/defaultmay10.asp Reference] (CF.AM-DISRUPTION) ACG=Anterior Cingulate Cortex,NC.AL.ACG (see [BrainCenterNC_ACG Anterior Cingulate Area]) AM=[BrainCenterFAM_FT_AM Amygdala,FAM.FT.AM] HC=Hippocampus,FMM.FT.HC (see [BrainCenterFMM_FT_HF Hippocampal Formation]) HT.L=Lateral Hypothalamic Area,LAC.FD.HT.LT (see [BrainCenterFD_HT Hypothalamus]) HT.PV=[BrainRegionLAC_FD_HT_PV Paraventricular Nucleus,LAC.FD.HT.PV] INS=[BrainCenterNC_INS Insular Cortex,NC.INS] LC=[BrainRegionLMC_HT_LC Locus Coeruleus,LMC.HT.LC] MPFC=Orbitofrontal Cortex,NC.AL.OPFC (see [BrainCenterNC_AL_OMPFC Orbitomedial Prefrontal Cortex]) PAG=[BrainRegionLMC_MM_PAG Periaqueductal Gray Matter,LMC.MM.PAG] PB=[BrainRegionLPC_HT_PRF_PB Parabrachial Nucleus,LPC.HT.PRF.PB] PUT=[BrainRegionTARGET_TEA_ENDOCRINE Endocrine Glands,TARGET.TEA.ENDOCRINE] SOL=[BrainRegionLPC_HL_SOL Solitary Nucleus,LPC.HL.SOL] TH=Thalamus,FD.TH unavailable = References = (generated) * https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 * http://www.surgicalneurologyint.com/article.asp?issn=2152-7806;year=2012;volume=3;issue=2;spage=40;epage=46;aulast=Langevin * http://neuropolitics.org/defaultmay10.asp