#summary Retrosplenial Cortex
@@[Home] -> [BiologicalLifeResearch] -> [BrainAreaNCP] -> [BrainRegionNCP_NC_MPL_RSC]
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This page covers biological details of component Retrosplenial Cortex.
Region is part of aHuman target integrated biological model.

  * *Top-down path to region*: Cerebral Cortex -> Parietal Lobe (NC.LOBE.PAR) -> [BrainCenterNC_MPL Medial Parietal Lobule] (NC.MPL) -> [BrainRegionNCP_NC_MPL_RSC Retrosplenial Cortex] (NCP.NC.MPL.RSC) (see [OverallMindMaps Mind Maps])
  * *Type*: cortex
  * *Quality*: L0
  * *Brain area*: [BrainAreaNCP Neocortical Brain - Conscious Personality Area] (NCP)
  * *Area circuit*: Mental Self (MSF)
  * *Brodmann ID*: 29,30
  * *Role*: cortex.generic
  * *Function*: Processing of emotionally salient stimuli
(generated)
= Components =
(generated)


  * no child items defined

= Connectivity =
(generated)


http://ahuman.org/svn/ahwiki/images/dot/NCP.NC.MPL.RSC.dot.png

*Inbound Region Connections:*

|| *Source Area* || *Source Region* || *Source Name* || *Type* || *Role* || *Reference* ||
|| [BrainAreaFAM FAM] || [BrainRegionFAM_FD_TH_PT FAM.FD.TH.PT] || Paratenial Nucleus of Thalamus || excitatory-glu || uncertain ||(unknown reference) ||
||  || [BrainRegionFAM_FT_SEP_MED FAM.FT.SEP.MED] || Medial Septal Nucleus || modulatory-ach || uncertain ||[http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F4.html Medial mammillary nucleus and theta rhythm (SEP -> RSP, abstract)] ||
|| [BrainAreaFMM FMM] || [BrainRegionFMM_FT_HF_SUBD FMM.FT.HF.SUBD] || Distal Subiculum || excitatory-glu || uncertain ||[http://www.nature.com/nrn/journal/v3/n2/fig_tab/nrn726_F3.html McNaughton Spatial Processing Network (SUB -> PCGRSP, abstract)] ||
|| [BrainAreaNCP NCP] || [BrainRegionNCP_FD_TH_AM NCP.FD.TH.AM] || Anteromedial Nucleus || excitatory-glu || uncertain ||[http://ahuman.org/svn/ahengine/research/articles/2009-Hippocampus-Thesis.pdf Hippocampal Formation (ATN -> Rsp, abstract)] ||
|| [BrainAreaNPE NPE] || [BrainRegionNPE_NC_SPL_PF NPE.NC.SPL.PF] || Rostral Precuneus || feedforward-glu || uncertain ||(unknown reference) ||
||  || [BrainRegionNPE_NC_SPL_PG NPE.NC.SPL.PG] || Caudal Precuneus || feedforward-glu || uncertain ||[http://www.nature.com/nrn/journal/v3/n2/fig_tab/nrn726_F3.html McNaughton Spatial Processing Network (PosteriorParietalCortex -> PCGRSP, abstract)] ||
|| [BrainAreaNSA NSA] || [BrainRegionNSA_NC_OCC_V1 NSA.NC.OCC.V1] || Primary Visual Cortex || feedforward-glu || uncertain ||[http://www.sciencedirect.com/science/article/pii/S1053811905008013 Category-Selectivity Paradigm (V1 -> RS)] ||

*Outbound Region Connections:*

|| *Target Area* || *Target Region* || *Target Name* || *Type* || *Role* || *Reference* ||
|| [BrainAreaFMM FMM] || [BrainRegionFMM_FD_TH_AD FMM.FD.TH.AD] || Anterodorsal Nucleus || excitatory-glu || uncertain || [http://www.scholarpedia.org/article/Head_direction_cells Head Direction Cell Circuit (RSP -> AD)] ||
||  || [BrainRegionFMM_FD_TH_AV FMM.FD.TH.AV] || Anteroventral Nucleus || excitatory-glu || uncertain || [http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F4.html Medial mammillary nucleus and theta rhythm (RSP -> AVTH)] ||
||  || [BrainRegionFMM_FD_TH_LD FMM.FD.TH.LD] || Lateral Dorsal Nucleus of Thalamus || excitatory-glu || uncertain || [http://www.scholarpedia.org/article/Head_direction_cells Head Direction Cell Circuit (RSP -> LD)] ||
||  || [BrainRegionFMM_FT_HC_CA1P FMM.FT.HC.CA1P] || Proximal CA1 of Hippocampus || excitatory-glu || uncertain || [https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 Prefrontal Cortex (PFC) in emotional behavior (PCA -> HCA, abstract)] ||
||  || [BrainRegionFMM_NC_PH_MEC FMM.NC.PH.MEC] || Medial Entorhinal Cortex || feedforward-glu || uncertain || [http://www.nature.com/nrn/journal/v3/n2/fig_tab/nrn726_F3.html McNaughton Spatial Processing Network (PCGRSP -> EnthCortex, abstract)] ||
||  || [BrainRegionFMM_NC_PH_POS FMM.NC.PH.POS] || Postsubiculum || feedforward-glu || uncertain || [http://www.scholarpedia.org/article/Head_direction_cells Head Direction Cell Circuit (RSP -> PSUB)] ||
|| [BrainAreaNDM NDM] || [BrainRegionNDM_NC_AL_DLPFCR NDM.NC.AL.DLPFCR] || Rostral Mid-Dorsolateral Prefrontal Cortex || feedforward-glu || uncertain || [https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 Prefrontal Cortex (PFC) in emotional behavior (PCA -> LPFC, abstract)] ||
||  || [BrainRegionNDM_NC_AL_ROFCR NDM.NC.AL.ROFCR] || Most Rostral Orbitofrontal Cortex || feedforward-glu || uncertain || [https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 Prefrontal Cortex (PFC) in emotional behavior (PCA -> OPFC, abstract)] ||

= Thirdparty Circuits =
(generated)

  * [http://www.nature.com/nrn/journal/v5/n1/images/nrn1299-f4.jpg Medial mammillary nucleus and theta rhythm] - see [http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F4.html Reference] (CT.MMB-THETA)

 AVTH=[BrainRegionFMM_FD_TH_AV Anteroventral Nucleus,FMM.FD.TH.AV]
 HF=[BrainCenterFMM_FT_HF Hippocampal Formation,FMM.FT.HF]
 MMB=[BrainRegionFMM_FD_MB_MMB Medial Mammillary Nucleus,FMM.FD.MB.MMB]
 RSP=[BrainRegionNCP_NC_MPL_RSC Retrosplenial Cortex,NCP.NC.MPL.RSC]
 SEP=[BrainCenterFAM_FT_SEP Septal Nuclei,FAM.FT.SEP]
 SupraMM=[BrainRegionLAC_FD_HT_SUM Supramammillary Nucleus,LAC.FD.HT.SUM]
 VTN=[BrainRegionLMC_MM_VTA Ventral Tegmental Area,LMC.MM.VTA]
<img src="http://www.nature.com/nrn/journal/v5/n1/images/nrn1299-f4.jpg" alt="unavailable" style="max-width: 100%;">

  * [http://www.scholarpedia.org/w/images/6/63/Taube_Figure_5a.png Head Direction Cell Circuit] - see [http://www.scholarpedia.org/article/Head_direction_cells Reference] (CT.HEAD-DIRECTION)

 AD=[BrainRegionFMM_FD_TH_AD Anterodorsal Nucleus,FMM.FD.TH.AD]
 DTN=[BrainRegionLMC_HT_TG_LDT Laterodorsal Tegmental Nucleus,LMC.HT.TG.DTG]
 EC=Entorhinal Cortex,FMM.NC.PH.ET (see [BrainCenterNC_PHA_RH Rhinal Cortex])
 HC=Hippocampus,FMM.FT.HC (see [BrainCenterFMM_FT_HF Hippocampal Formation])
 IPD=[BrainRegionFEC_HT_TG_IPD Interpeduncular Nucleus,FEC.HT.TG.IPD]
 LD=[BrainRegionFMM_FD_TH_LD Lateral Dorsal Nucleus of Thalamus,FMM.FD.TH.LD]
 LHAB=[BrainCenterFAM_FD_HB Habenula,FAM.FD.HB]
 LMB=[BrainRegionFMM_FD_MB_LMB Lateral Mammillary Nucleus,FMM.FD.MB.LMB]
 MVSN=[BrainRegionLPC_HT_MVBN Medial Vestibular Nucleus,LPC.HT.MVBN]
 NPRP=[BrainRegionLRC_HL_NPH Prepositus Nucleus,LRC.HL.NPH]
 PC=Parietal Lobe,NC.LOBE.PAR
 PRHC=[BrainRegionFMM_NC_PH_POR Postrhinal Cortex,FMM.NC.PH.POR]
 PSUB=[BrainRegionFMM_NC_PH_POS Postsubiculum,FMM.NC.PH.POS]
 RSP=[BrainRegionNCP_NC_MPL_RSC Retrosplenial Cortex,NCP.NC.MPL.RSC]
 SUPGEN=[BrainRegionNSA_FD_TH_SG Suprageniculate Nucleus of Thalamus,NSA.FD.TH.SG]
 VC=[BrainCenterNC_LOBE_OCC Occipital Lobe,NC.LOBE.OCC]
<img src="http://www.scholarpedia.org/w/images/6/63/Taube_Figure_5a.png" alt="unavailable" style="max-width: 100%;">

  * [http://www.nature.com/nrn/journal/v3/n2/images/nrn726-f3.jpg McNaughton Spatial Processing Network] - see [http://www.nature.com/nrn/journal/v3/n2/fig_tab/nrn726_F3.html Reference] (CP.VISUAL-SPATIAL-PROCESSING)

 EnthCortex=Entorhinal Cortex,FMM.NC.PH.ET (see [BrainCenterNC_PHA_RH Rhinal Cortex])
 HF=[BrainCenterFMM_FT_HF Hippocampal Formation,FMM.FT.HF]
 ITCortex=[BrainCenterNSA_NC_IT Inferotemporal Area,NSA.NC.IT]
 PCGRSP=[BrainCenterNC_MPL Medial Parietal Lobule,NC.MPL]
 ParInsVestCortex=[BrainRegionNSA_NC_IPS_VIP Ventral Intraparietal Sulcus,NSA.NC.IPS.VIP]
 PosteriorParietalCortex=[BrainRegionNPE_NC_SPL_PG Caudal Precuneus,NPE.NC.SPL.PG]
 SUB=Subiculum,FMM.FT.HF.SUB (see [BrainCenterFMM_FT_HF Hippocampal Formation])
 SomSensCortex=[BrainRegionNCP_NC_PG_S1 Primary Somatosensory Cortex,NCP.NC.PG.S1]
 VisualCortex=[BrainCenterNC_LOBE_OCC Occipital Lobe,NC.LOBE.OCC]
<img src="http://www.nature.com/nrn/journal/v3/n2/images/nrn726-f3.jpg" alt="unavailable" style="max-width: 100%;">

  * [http://ars.els-cdn.com/content/image/1-s2.0-S0959438808001566-gr1.jpg Global visual system] - see [http://www.sciencedirect.com/science/article/pii/S0959438808001566 Reference] (CP.GLOBAL-VISUAL-SYSTEM)

 ATH=Anterior Nucleus of Thalamus,FD.TH.AN (see [BrainCenterFD_TH_CR Cognitive Thalamus])
 BGA=[BrainCenterFEC_FT_BG Basal Ganglia,FEC.FT.BG]
 FrontalCortex=Anterior Lobe,NC.LOBE.ANT
 LGN=[BrainRegionNSA_FD_LGN Lateral Geniculate Nucleus,NSA.FD.LGN]
 OPN=[BrainRegionLPC_MM_OCN Oculomotor Nucleus,LPC.MM.OCN]
 ParietalCortex=Parietal Lobe,NC.LOBE.PAR
 Pulvinar=Pulvinar,FD.PV (see [BrainCenterFD_TH_SR Sensory Thalamus])
 RF=[BrainCenterHT_RF Pontine Reticular Formation,HT.RF]
 Retina=[BrainRegionLPC_FD_RT Retinal Nucleus,LPC.FD.RT]
 SCi=Superior Colliculus,MM.SC (see [BrainCenterMM_REF Reflexes Nuclei of Midbrain Mesencephalon])
 SCs=Superior Colliculus,MM.SC (see [BrainCenterMM_REF Reflexes Nuclei of Midbrain Mesencephalon])
 SNc=[BrainRegionFEC_FT_SNC_LT Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT]
 SNr=[BrainRegionFEC_FT_SNR_DL Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL]
 SpinalCord=Lamina IX,SC.VH.L9 (see [BrainCenterSC_VH Anterior/Ventral Horn])
 Striatum=Striatum,FEC.FT.ST (see [BrainCenterFEC_FT_BG Basal Ganglia])
 VisualCortex=[BrainCenterNC_LOBE_OCC Occipital Lobe,NC.LOBE.OCC]
<img src="http://ars.els-cdn.com/content/image/1-s2.0-S0959438808001566-gr1.jpg" alt="unavailable" style="max-width: 100%;">

  * [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/emotional_top.jpg Prefrontal Cortex (PFC) in emotional behavior] - see [https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 Reference] (CF.PFC-EMOTIONS)

 ACG=Anterior Cingulate Cortex,NC.AL.ACG (see [BrainCenterNC_ACG Anterior Cingulate Area])
 AM=[BrainCenterFAM_FT_AM Amygdala,FAM.FT.AM]
 HCA=Hippocampus,FMM.FT.HC (see [BrainCenterFMM_FT_HF Hippocampal Formation])
 HT=[BrainCenterFD_HT Hypothalamus,FD.HT]
 LPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see [BrainCenterNC_AL_LPFC Lateral Prefrontal Cortex])
 OPFC=Orbitofrontal Cortex,NC.AL.OPFC (see [BrainCenterNC_AL_OMPFC Orbitomedial Prefrontal Cortex])
 PCA=[BrainCenterNC_MPL Medial Parietal Lobule,NC.MPL]
 PN=Pontine Nuclear Complex,HT.PN (see [BrainCenterHT_SN Metencephalic Sensory Nuclei])
 TH=Mediodorsal Nucleus of Thalamus,FD.TH.MD (see [BrainCenterFD_TH_CR Cognitive Thalamus])
<img src="http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/emotional_top.jpg" alt="unavailable" style="max-width: 100%;">

  * [http://ars.els-cdn.com/content/image/1-s2.0-S0149763409002061-gr1.jpg Contribution of hippocampal region CA3 to consciousness] - see [http://www.sciencedirect.com/science/article/pii/S0149763409002061 Reference] (CT.HIPPOCAMPUS-FOR-CONSCIOUSNESS)

 AnteriorHC=Hippocampus,FMM.FT.HC (see [BrainCenterFMM_FT_HF Hippocampal Formation])
 AnteriorTemporal=[BrainRegionNCP_NC_INS_HR Anterior Temporal Lobe,NCP.NC.INS.HR]
 CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (see [BrainCenterFMM_FT_HF Hippocampal Formation])
 CA3=Dorsomedial Cornu Ammonis of Hippocampus,FMM.FT.HC.CA3 (see [BrainCenterFMM_FT_HF Hippocampal Formation])
 IPL=[BrainCenterNC_IPL Inferior Parietal Lobule,NC.IPL]
 LateralEC=Entorhinal Cortex,FMM.NC.PH.ET (see [BrainCenterNC_PHA_RH Rhinal Cortex])
 MB=Mammillary Body,FD.MB (see [BrainCenterFD_HT Hypothalamus])
 MedialEC=Entorhinal Cortex,FMM.NC.PH.ET (see [BrainCenterNC_PHA_RH Rhinal Cortex])
 PHCortex=[BrainRegionFMM_NC_PH_POR Postrhinal Cortex,FMM.NC.PH.POR]
 PRCortex=[BrainRegionFMM_NC_PH_PER Perirhinal Cortex,FMM.NC.PH.PER]
 PosteriorCingulate=[BrainRegionNCP_NC_MPL_PSCG Posterior Cingulate Cortex,NCP.NC.MPL.PSCG]
 PosteriorHC=Hippocampus,FMM.FT.HC (see [BrainCenterFMM_FT_HF Hippocampal Formation])
 Retrosplenial=[BrainRegionNCP_NC_MPL_RSC Retrosplenial Cortex,NCP.NC.MPL.RSC]
 TH.AV=[BrainRegionFMM_FD_TH_AV Anteroventral Nucleus,FMM.FD.TH.AV]
<img src="http://ars.els-cdn.com/content/image/1-s2.0-S0149763409002061-gr1.jpg" alt="unavailable" style="max-width: 100%;">

  * [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/brain/HF.jpg Hippocampal Formation] - see [article:2009-Hippocampus-Thesis.pdf Reference] (CT.HIPPOCAMPAL-FORMATION)

 ATN=Anterior Nucleus of Thalamus,FD.TH.AN (see [BrainCenterFD_TH_CR Cognitive Thalamus])
 CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (see [BrainCenterFMM_FT_HF Hippocampal Formation])
 CA3=Dorsomedial Cornu Ammonis of Hippocampus,FMM.FT.HC.CA3 (see [BrainCenterFMM_FT_HF Hippocampal Formation])
 DG=[BrainRegionFMM_FT_HC_DG Dentate Gyrus,FMM.FT.HC.DG]
 DTN=[BrainRegionLMC_HT_TG_LDT Laterodorsal Tegmental Nucleus,LMC.HT.TG.LDT]
 EC=Entorhinal Cortex,FMM.NC.PH.ET (see [BrainCenterNC_PHA_RH Rhinal Cortex])
 LDN=[BrainRegionFMM_FD_TH_LD Lateral Dorsal Nucleus of Thalamus,FMM.FD.TH.LD]
 LMam=[BrainRegionFMM_FD_MB_LMB Lateral Mammillary Nucleus,FMM.FD.MB.LMB]
 PoS=[BrainRegionFMM_NC_PH_POS Postsubiculum,FMM.NC.PH.POS]
 Rsp=[BrainRegionNCP_NC_MPL_RSC Retrosplenial Cortex,NCP.NC.MPL.RSC]
 Sub=Subiculum,FMM.FT.HF.SUB (see [BrainCenterFMM_FT_HF Hippocampal Formation])
<img src="http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/brain/HF.jpg" alt="unavailable" style="max-width: 100%;" height=300 width=300>

  * [http://ars.els-cdn.com/content/image/1-s2.0-S1053811905008013-gr5.jpg Category-Selectivity Paradigm] - see [http://www.sciencedirect.com/science/article/pii/S1053811905008013 Reference] (CT.CATEGORY-SELECTIVITY)

 FFA=Fusiform Gyrus,NSA.NC.OCC.V4 (see [BrainCenterNC_LOBE_OCC Occipital Lobe])
 IOG=[BrainRegionNSA_NC_OCC_MT Middle Temporal Area,NSA.NC.OCC.MT]
 PPA=Parahippocampal Lobe,NC.LOBE.PH
 RS=[BrainRegionNCP_NC_MPL_RSC Retrosplenial Cortex,NCP.NC.MPL.RSC]
 STS=[BrainCenterNC_STG Superior Temporal Gyrus,NC.STG]
 V1=[BrainRegionNSA_NC_OCC_V1 Primary Visual Cortex,NSA.NC.OCC.V1]
<img src="http://ars.els-cdn.com/content/image/1-s2.0-S1053811905008013-gr5.jpg" alt="unavailable" style="max-width: 100%;">

  * [http://www.nature.com/npp/journal/v35/n1/images/npp2009104f10.jpg Medial prefrontal network] - see [http://www.nature.com/npp/journal/v35/n1/fig_tab/npp2009104f10.html Reference] (CF.DEFAULT-SYSTEM)

 BNST=[BrainRegionFAM_FT_BNST Bed Nucleus of Stria Terminalis,FAM.FT.BNST]
 MPFC=Orbitofrontal Cortex,NC.AL.OPFC (see [BrainCenterNC_AL_OMPFC Orbitomedial Prefrontal Cortex])
 NACC=Accumbens Nucleus,FEC.FT.ACC (see [BrainCenterFEC_FT_BG Basal Ganglia])
 PCG=[BrainRegionNCP_NC_MPL_PSCG Posterior Cingulate Cortex,NCP.NC.MPL.PSCG]
 PH=Parahippocampal Lobe,NC.LOBE.PH
 RSP=[BrainRegionNCP_NC_MPL_RSC Retrosplenial Cortex,NCP.NC.MPL.RSC]
 RostralCtx=[BrainRegionNCP_NC_TPC Temporopolar Cortex,NCP.NC.TPC]
 TH.MD=Mediodorsal Nucleus of Thalamus,FD.TH.MD (see [BrainCenterFD_TH_CR Cognitive Thalamus])
 TH.PV=[BrainRegionNDM_FD_TH_PV Paraventricular Nucleus of Thalamus,NDM.FD.TH.PV]
 VPAL=Ventral Pallidum,FEC.FT.VP (see [BrainCenterFEC_FT_BG Basal Ganglia])
<img src="http://www.nature.com/npp/journal/v35/n1/images/npp2009104f10.jpg" alt="unavailable" style="max-width: 100%;">


= References =
(generated)

  * http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F4.html
  * http://www.scholarpedia.org/article/Head_direction_cells
  * http://www.nature.com/nrn/journal/v3/n2/fig_tab/nrn726_F3.html
  * http://www.sciencedirect.com/science/article/pii/S0959438808001566
  * https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988
  * http://www.sciencedirect.com/science/article/pii/S0149763409002061
  * article:2009-Hippocampus-Thesis.pdf
  * http://www.sciencedirect.com/science/article/pii/S1053811905008013
  * http://www.nature.com/npp/journal/v35/n1/fig_tab/npp2009104f10.html