#summary Posterior Insular Cortex
@@[Home] -> [BiologicalLifeResearch] -> [BrainAreaNCP] -> [BrainRegionNCP_NC_INS_PIC]
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This page covers biological details of component Posterior Insular Cortex.
Region is part of aHuman target integrated biological model.

  * *Top-down path to region*: Cerebral Cortex -> Temporal Lobe (NC.LOBE.TEMP) -> [BrainCenterNC_INS Insular Cortex] (NC.INS) -> [BrainRegionNCP_NC_INS_PIC Posterior Insular Cortex] (NCP.NC.INS.PIC) (see [OverallMindMaps Mind Maps])
  * *Type*: cortex
  * *Quality*: L0
  * *Brain area*: [BrainAreaNCP Neocortical Brain - Conscious Personality Area] (NCP)
  * *Area circuit*: Body Self (BSF)
  * *Brodmann ID*: 13
  * *Role*: cortex.sensory.primary
  * *Function*: Awareness and sensation of pain
(generated)
= Components =
(generated)


  * no child items defined

= Connectivity =
(generated)


http://ahuman.org/svn/ahwiki/images/dot/NCP.NC.INS.PIC.dot.png

*Inbound Region Connections:*

|| *Source Area* || *Source Region* || *Source Name* || *Type* || *Role* || *Reference* ||
|| [BrainAreaLPC LPC] || [BrainRegionLPC_HT_PRF_PB LPC.HT.PRF.PB] || Parabrachial Nucleus || excitatory-glu || uncertain ||[http://www.sciencedirect.com/science/article/pii/S0149763401000215 Gustatory sensory system of rat and macaque (PB -> Gud, abstract)] ||
|| [BrainAreaNCP NCP] || [BrainRegionNCP_FD_TH_VPI NCP.FD.TH.VPI] || Ventral Posteroinferior Nucleus || excitatory-glu || uncertain ||[http://users.atw.hu/blp6/BLP6/HTML/C0079780323045827.htm Pain matrix (TH.VPI -> INS)] ||
||  || [BrainRegionNCP_FD_TH_VPM NCP.FD.TH.VPM] || Ventral Posteromedial Nucleus || excitatory-glu || uncertain ||[http://neuropolitics.org/defaultmay10.asp Amygdalar disruption of prefrontal cortex (TH -> INS, abstract)] ||
||  || [BrainRegionNCP_NC_SPL_SA NCP.NC.SPL.SA] || Somatosensory Association Cortex || feedforward-glu || uncertain ||(unknown reference) ||

*Outbound Region Connections:*

|| *Target Area* || *Target Region* || *Target Name* || *Type* || *Role* || *Reference* ||
|| [BrainAreaFAM FAM] || [BrainRegionFAM_FT_AM_BM FAM.FT.AM.BM] || Magnocellular Basal Amygdaloid Nucleus || excitatory-glu || uncertain || [http://www.nature.com/nrn/journal/v14/n7/fig_tab/nrn3516_F2.html Afferent pain pathways (Insula -> AMY, abstract)] ||
|| [BrainAreaNCP NCP] || [BrainRegionNCP_NC_INS_AIC NCP.NC.INS.AIC] || Anterior Insular Cortex || feedforward-glu || uncertain || [http://www.sciencedirect.com/science/article/pii/S0149763401000215 Gustatory sensory system of rat and macaque (Iav -> IadIap, abstract)] ||
||  || [BrainRegionNCP_NC_INS_PPC NCP.NC.INS.PPC] || Peripaleocortical Claustral || feedforward-glu || uncertain || [http://www.sciencedirect.com/science/article/pii/S0149763401000215 Gustatory sensory system of rat and macaque (Iav -> IadIap, abstract)] ||

= Thirdparty Circuits =
(generated)

  * [http://ars.els-cdn.com/content/image/1-s2.0-S0149763401000215-gr4a.gif Gustatory sensory system of rat and macaque] - see [http://www.sciencedirect.com/science/article/pii/S0149763401000215 Reference] (CP.GUSTATORY-OLFACTORY)

 EnP=[BrainRegionFAM_FT_EPF Endopiriform Nucleus,FAM.FT.EPF]
 Gud=[BrainCenterNC_INS Insular Cortex,NC.INS]
 Gug=[BrainCenterNC_INS Insular Cortex,NC.INS]
 HF=[BrainCenterFMM_FT_HF Hippocampal Formation,FMM.FT.HF]
 IadIap=[BrainCenterNC_INS Insular Cortex,NC.INS]
 Iav=[BrainCenterNC_INS Insular Cortex,NC.INS]
 NST=[BrainRegionLPC_HL_SOL Solitary Nucleus,LPC.HL.SOL]
 PB=[BrainRegionLPC_HT_PRF_PB Parabrachial Nucleus,LPC.HT.PRF.PB]
 PiR=[BrainRegionNSA_NC_PH_PIR Piriform Cortex,NSA.NC.PH.PIR]
 PrC=[BrainRegionFMM_NC_PH_PER Perirhinal Cortex,FMM.NC.PH.PER]
 VPMpc=[BrainRegionNCP_FD_TH_VPM Ventral Posteromedial Nucleus,NCP.FD.TH.VPM]
<img src="http://ars.els-cdn.com/content/image/1-s2.0-S0149763401000215-gr4a.gif" alt="unavailable" style="max-width: 100%;">

  * [http://www.nature.com/nrn/journal/v14/n7/images/nrn3516-f2.jpg Afferent pain pathways] - see [http://www.nature.com/nrn/journal/v14/n7/fig_tab/nrn3516_F2.html Reference] (CF.PAIN-PATH)

 ACC=Anterior Cingulate Cortex,NC.AL.ACG (see [BrainCenterNC_ACG Anterior Cingulate Area])
 AMY=[BrainCenterFAM_FT_AM Amygdala,FAM.FT.AM]
 BG=[BrainCenterFEC_FT_BG Basal Ganglia,FEC.FT.BG]
 Cerebellum=[BrainCenterLLC_HT_CRC Cerebellar Complex,LLC.HT.CRC]
 Insula=[BrainCenterNC_INS Insular Cortex,NC.INS]
 PAG=[BrainRegionLMC_MM_PAG Periaqueductal Gray Matter,LMC.MM.PAG]
 PB=[BrainRegionLPC_HT_PRF_PB Parabrachial Nucleus,LPC.HT.PRF.PB]
 PFC=Prefrontal Cortex,NC.AL.PFC
 S1=[BrainRegionNCP_NC_PG_S1 Primary Somatosensory Cortex,NCP.NC.PG.S1]
 S2=[BrainRegionNCP_NC_PG_S2 Secondary Somatosensory Cortex,NCP.NC.PG.S2]
 SC=[BrainCenterBMA_SC_PH Posterior/Dorsal Horn,BMA.SC.PH]
 Thalamus=[BrainCenterFD_TH_SR Sensory Thalamus,FD.TH.SR]
<img src="http://www.nature.com/nrn/journal/v14/n7/images/nrn3516-f2.jpg" alt="unavailable" style="max-width: 100%;">

  * [http://users.atw.hu/blp6/BLP6/HTML/common/M9780323045827-007-f005.jpg Pain matrix] - see [http://users.atw.hu/blp6/BLP6/HTML/C0079780323045827.htm Reference] (CF.SOMATOSENSORY-THALAMUS)

 INS=[BrainRegionNCP_NC_INS_PIC Posterior Insular Cortex,NCP.NC.INS.PIC]
 S1=[BrainRegionNCP_NC_PG_S1 Primary Somatosensory Cortex,NCP.NC.PG.S1]
 TH.VPI=[BrainRegionNCP_FD_TH_VPI Ventral Posteroinferior Nucleus,NCP.FD.TH.VPI]
 TH.VPL=[BrainRegionNCP_FD_TH_VPL Ventral Posterolateral Nucleus,NCP.FD.TH.VPL]
 TH.VPM=[BrainRegionNCP_FD_TH_VPM Ventral Posteromedial Nucleus,NCP.FD.TH.VPM]
<img src="http://users.atw.hu/blp6/BLP6/HTML/common/M9780323045827-007-f005.jpg" alt="unavailable" style="max-width: 100%;">


= References =
(generated)

  * http://www.sciencedirect.com/science/article/pii/S0149763401000215
  * http://www.nature.com/nrn/journal/v14/n7/fig_tab/nrn3516_F2.html
  * http://users.atw.hu/blp6/BLP6/HTML/C0079780323045827.htm