#summary Lower Marginal Nucleus @@[Home] -> [BiologicalLifeResearch] -> [BrainAreaLPC] -> [BrainRegionLPC_SC_PH_LMG] ---- This page covers biological details of component Lower Marginal Nucleus. Region is part of aHuman target integrated biological model. * *Top-down path to region*: Spinal Cord -> [BrainCenterBMA_SC_PH Posterior/Dorsal Horn] (BMA.SC.PH) -> Lamina I (LPC.SC.PH.L1) -> Marginal Nucleus (LPC.SC.PH.MG) -> [BrainRegionLPC_SC_PH_LMG Lower Marginal Nucleus] (LPC.SC.PH.LMG) (see [OverallMindMaps Mind Maps]) * *Type*: nucleus * *Quality*: L0 * *Brain area*: [BrainAreaLPC Lower Brain - Peripheral Control Area] (LPC) * *Area circuit*: Lower Body Conscious Sensations (SBL) * *Role*: sensory.nucleus * *Function*: Relay information related to pain and temperature sensation - T7-T12,L1-L5,S1-S5,CX (generated) = Components = (generated) * no child items defined = Connectivity = (generated) http://ahuman.org/svn/ahwiki/images/dot/LPC.SC.PH.LMG.dot.png *Inbound Region Connections:* || *Source Area* || *Source Region* || *Source Name* || *Type* || *Role* || *Reference* || || [BrainAreaLMC LMC] || [BrainRegionLMC_HL_RP_PL LMC.HL.RP.PL] || Raphe Pallidus Nucleus || modulatory-5ht || uncertain ||(unknown reference) || || [BrainAreaLPC LPC] || [BrainRegionLPC_PN_SG_LDRG LPC.PN.SG.LDRG] || Lower Dorsal Root Ganglion || excitatory-glu || uncertain ||(unknown reference) || *Outbound Region Connections:* || *Target Area* || *Target Region* || *Target Name* || *Type* || *Role* || *Reference* || || [BrainAreaNCP NCP] || [BrainRegionNCP_FD_TH_LI NCP.FD.TH.LI] || Limitans Nucleus of Thalamus || excitatory-glu || uncertain || [http://www.nature.com/nrn/journal/v14/n7/fig_tab/nrn3516_F2.html Afferent pain pathways (SC -> Thalamus, abstract)] || || || [BrainRegionNCP_FD_TH_VPI NCP.FD.TH.VPI] || Ventral Posteroinferior Nucleus || excitatory-glu || uncertain || [http://www.nature.com/nrn/journal/v14/n7/fig_tab/nrn3516_F2.html Afferent pain pathways (SC -> Thalamus, abstract)] || || || [BrainRegionNCP_FD_TH_VPL NCP.FD.TH.VPL] || Ventral Posterolateral Nucleus || excitatory-glu || uncertain || [http://www.nature.com/nrn/journal/v14/n7/fig_tab/nrn3516_F2.html Afferent pain pathways (SC -> Thalamus, abstract)] || || [BrainAreaNDM NDM] || [BrainRegionNDM_FD_TH_SM NDM.FD.TH.SM] || Submedial Nucleus of Thalamus || excitatory-glu || uncertain || [http://www.nature.com/nrn/journal/v14/n7/fig_tab/nrn3516_F2.html Afferent pain pathways (SC -> Thalamus, abstract)] || = Thirdparty Circuits = (generated) * [http://www.nature.com/nrn/journal/v14/n7/images/nrn3516-f2.jpg Afferent pain pathways] - see [http://www.nature.com/nrn/journal/v14/n7/fig_tab/nrn3516_F2.html Reference] (CF.PAIN-PATH) ACC=Anterior Cingulate Cortex,NC.AL.ACG (see [BrainCenterNC_ACG Anterior Cingulate Area]) AMY=[BrainCenterFAM_FT_AM Amygdala,FAM.FT.AM] BG=[BrainCenterFEC_FT_BG Basal Ganglia,FEC.FT.BG] Cerebellum=[BrainCenterLLC_HT_CRC Cerebellar Complex,LLC.HT.CRC] Insula=[BrainCenterNC_INS Insular Cortex,NC.INS] PAG=[BrainRegionLMC_MM_PAG Periaqueductal Gray Matter,LMC.MM.PAG] PB=[BrainRegionLPC_HT_PRF_PB Parabrachial Nucleus,LPC.HT.PRF.PB] PFC=Prefrontal Cortex,NC.AL.PFC S1=[BrainRegionNCP_NC_PG_S1 Primary Somatosensory Cortex,NCP.NC.PG.S1] S2=[BrainRegionNCP_NC_PG_S2 Secondary Somatosensory Cortex,NCP.NC.PG.S2] SC=[BrainCenterBMA_SC_PH Posterior/Dorsal Horn,BMA.SC.PH] Thalamus=[BrainCenterFD_TH_SR Sensory Thalamus,FD.TH.SR] unavailable = References = (generated) * http://www.nature.com/nrn/journal/v14/n7/fig_tab/nrn3516_F2.html