#summary Dorsal Raphe Nucleus
@@[Home] -> [BiologicalLifeResearch] -> [BrainAreaLMC] -> [BrainRegionLMC_MM_RP_DRN]
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This page covers biological details of component Dorsal Raphe Nucleus.
Region is part of aHuman target integrated biological model.
* *Top-down path to region*: Midbrain Mesencephalon -> [BrainCenterMM_RF Mesencephalic Reticular Formation] (MM.RF) -> Mesencephalic Reticular Formation, Midline Column (MM.RF.MID) -> [BrainRegionLMC_MM_RP_DRN Dorsal Raphe Nucleus] (LMC.MM.RP.DRN) (see [OverallMindMaps Mind Maps])
* *Type*: nucleus
* *Quality*: L0
* *Brain area*: [BrainAreaLMC Lower Brain - Modulatory Contol Area] (LMC)
* *Area circuit*: Serotonin - Feelings of Well-Being and Happiness (5HT)
* *Role*: processor.autonomic
* *Function*: Regulation of sleep and mood
* *Notes to function*:
* Major source of 5HT
* inhibitory nucleus
(generated)
= Components =
(generated)
*Component items*:
* *Serotonergic cell group B7*
= Connectivity =
(generated)
http://ahuman.org/svn/ahwiki/images/dot/LMC.MM.RP.DRN.dot.png
*Inbound Region Connections:*
|| *Source Area* || *Source Region* || *Source Name* || *Type* || *Role* || *Reference* ||
|| [BrainAreaFAM FAM] || [BrainRegionFAM_FD_LHB_MED FAM.FD.LHB.MED] || Lateral Habenula Medial Part || excitatory-glu || uncertain ||[http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Both LHb and MHb control the dopaminergic and serotonergic systems (LHbM -> DRN)] ||
|| [BrainAreaFEC FEC] || [BrainRegionFEC_HT_TG_IPD FEC.HT.TG.IPD] || Interpeduncular Nucleus || modulatory-ach || uncertain ||[http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Both LHb and MHb control the dopaminergic and serotonergic systems (IPN -> DRN)] ||
|| || [BrainRegionFEC_HT_TG_RMTG FEC.HT.TG.RMTG] || Rostromedial Tegmental Nucleus || inhibitory-gaba || uncertain ||[http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Both LHb and MHb control the dopaminergic and serotonergic systems (RMTg -> DRN)] ||
|| [BrainAreaLLC LLC] || [BrainRegionLLC_FD_TH_SF LLC.FD.TH.SF] || Subfascicular Nucleus of Thalamus || inhibitory-gaba || uncertain ||(unknown reference) ||
|| [BrainAreaLMC LMC] || [BrainRegionLMC_HP_RP_LI LMC.HP.RP.LI] || Raphe Nucleus Linearis || modulatory-5ht || uncertain ||(unknown reference) ||
*Outbound Region Connections:*
|| *Target Area* || *Target Region* || *Target Name* || *Type* || *Role* || *Reference* ||
|| [BrainAreaNDM NDM] || [BrainRegionNDM_FD_TH_PV NDM.FD.TH.PV] || Paraventricular Nucleus of Thalamus || modulatory-5ht || uncertain || (unknown reference) ||
= Thirdparty Circuits =
(generated)
* [http://www.nature.com/neuro/journal/v17/n9/images/nn.3779-F2.jpg Both LHb and MHb control the dopaminergic and serotonergic systems] - see [http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Reference] (CF.HB-DA5HT)
DBB=[BrainRegionFAM_FT_SEP_DBB Diagonal Band of Broca,FAM.FT.SEP.DBB]
DRN=[BrainRegionLMC_MM_RP_DRN Dorsal Raphe Nucleus,LMC.MM.RP.DRN]
GPb=Dorsal Pallidum,FEC.FT.DP (see [BrainCenterFEC_FT_BG Basal Ganglia])
IPN=[BrainRegionFEC_HT_TG_IPD Interpeduncular Nucleus,FEC.HT.TG.IPD]
LHA=[BrainRegionLAC_FD_HT_LTN Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]
LHbL=[BrainRegionFAM_FD_LHB_LT Lateral Habenula Lateral Part,FAM.FD.LHB.LT]
LHbM=[BrainRegionFAM_FD_LHB_MED Lateral Habenula Medial Part,FAM.FD.LHB.MED]
LPO=[BrainRegionLAC_FD_HT_VLPO Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO]
LS=[BrainRegionFAM_FT_SEP_LT Lateral Septal Nucleus,FAM.FT.SEP.LT]
MHb=[BrainRegionFAM_FD_MHB Medial Habenula,FAM.FD.MHB]
MRN=Raphe Nuclei of Medulla,LMC.HL.RP (see [BrainCenterHL_RF Medullary Reticular Formation])
MS=[BrainRegionFAM_FT_SEP_MED Medial Septal Nucleus,FAM.FT.SEP.MED]
PS=Posterior Septal Group,FAM.FT.SEP.PG (see [BrainCenterFAM_FT_SEP Septal Nuclei])
RMTg=[BrainRegionFEC_HT_TG_RMTG Rostromedial Tegmental Nucleus,FEC.HT.TG.RMTG]
SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see [BrainCenterFEC_FT_BG Basal Ganglia])
VP=Ventral Pallidum,FEC.FT.VP (see [BrainCenterFEC_FT_BG Basal Ganglia])
VTA=[BrainRegionLMC_MM_VTA Ventral Tegmental Area,LMC.MM.VTA]
* [http://www.scholarpedia.org/w/images/thumb/2/2d/Hb-connections-small.jpg/800px-Hb-connections-small.jpg Habenula Connections] - see [http://www.scholarpedia.org/article/Habenula Reference] (CF.HB-CONNECTIONS)
CPu=Striatum,FEC.FT.ST (see [BrainCenterFEC_FT_BG Basal Ganglia])
DBB=[BrainRegionFAM_FT_SEP_DBB Diagonal Band of Broca,FAM.FT.SEP.DBB]
DR=[BrainRegionLMC_MM_RP_DRN Dorsal Raphe Nucleus,LMC.MM.RP.DRN]
GPi=Globus Pallidus Internal,FEC.FT.GPI (see [BrainCenterFEC_FT_BG Basal Ganglia])
IP=[BrainRegionFEC_HT_TG_IPD Interpeduncular Nucleus,FEC.HT.TG.IPD]
LH=Lateral Hypothalamic Area,LAC.FD.HT.LT (see [BrainCenterFD_HT Hypothalamus])
LHb=Lateral Habenula,FAM.FD.LHB (see [BrainCenterFAM_FD_HB Habenula])
LPO=[BrainRegionLAC_FD_HT_VLPO Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO]
MHb=[BrainRegionFAM_FD_MHB Medial Habenula,FAM.FD.MHB]
MR=[BrainRegionLMC_MM_RP_SUC Superior Central Raphe Nucleus,LMC.MM.RP.SUC]
PB=[BrainRegionTARGET_TEA_ENDOCRINE Endocrine Glands,TARGET.TEA.ENDOCRINE]
S=[BrainCenterFAM_FT_SEP Septal Nuclei,FAM.FT.SEP]
SNc=[BrainRegionFEC_FT_SNC_LT Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT]
VTA=[BrainRegionLMC_MM_VTA Ventral Tegmental Area,LMC.MM.VTA]
= References =
(generated)
* http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html
* http://www.scholarpedia.org/article/Habenula