#summary Pontine Reticulotegmental Nucleus
@@[Home] -> [BiologicalLifeResearch] -> [BrainAreaLLC] -> [BrainRegionLLC_HT_PRF_RTMG]
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This page covers biological details of component Pontine Reticulotegmental Nucleus.
Region is part of aHuman target integrated biological model.

  * *Top-down path to region*: Hindbrain Metencephalon -> [BrainCenterHT_RF Pontine Reticular Formation] (HT.RF) -> Pontine Reticular Formation, Lateral Column (HT.RF.LAT) -> [BrainRegionLLC_HT_PRF_RTMG Pontine Reticulotegmental Nucleus] (LLC.HT.PRF.RTMG) (see [OverallMindMaps Mind Maps])
  * *Type*: nucleus
  * *Quality*: L0
  * *Brain area*: [BrainAreaLLC Lower Brain - Locomotion Control Area] (LLC)
  * *Area circuit*: Cerebrocerebellar Locomotion (LLC)
  * *Role*: processor.automatic
  * *Function*: Mediate saccadic eye movements
  * *Comments*: Nucleus of Bechterew, tegmentopontine reticular nucleus, projections from superior colliculus to vermis of CR
  * *Notes to function*: 
   * Inactivation leads to deficit of expression, but not learning
(generated)
= Components =
(generated)


  * no child items defined

= Connectivity =
(generated)


http://ahuman.org/svn/ahwiki/images/dot/LLC.HT.PRF.RTMG.dot.png

*Inbound Region Connections:*

|| *Source Area* || *Source Region* || *Source Name* || *Type* || *Role* || *Reference* ||
|| [BrainAreaFMM FMM] || [BrainRegionFMM_FD_MB_LMB FMM.FD.MB.LMB] || Lateral Mammillary Nucleus || excitatory-glu || uncertain ||[http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/mb.jpg Mammillary Body (LMB -> RTG)] ||
||  || [BrainRegionFMM_FD_MB_MMB FMM.FD.MB.MMB] || Medial Mammillary Nucleus || excitatory-glu || uncertain ||[http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/mb.jpg Mammillary Body (MMB -> RTG)] ||
|| [BrainAreaLPC LPC] || [BrainRegionLPC_HL_TGS_STR LPC.HL.TGS.STR] || Spinal Trigeminal Nucleus || excitatory-glu || uncertain ||[http://neuroscience.uth.tmc.edu/s3/chapter07.html Eye blink reflex and pupillary light reflex (SpinalTrigeminal -> RF, abstract)] ||
|| [BrainAreaLRC LRC] || [BrainRegionLRC_MM_SC_DEEP LRC.MM.SC.DEEP] || Deep Superior Colliculus || excitatory-glu || uncertain ||[http://www.sciencedirect.com/science/article/pii/S0387760401003308 Geniculate and Extyrageniculate Paths (SC -> RF, abstract)] ||
||  || [BrainRegionLRC_MM_SC_INT LRC.MM.SC.INT] || Intermediate Superior Colliculus || excitatory-glu || uncertain ||[http://www.sciencedirect.com/science/article/pii/S0387760401003308 Geniculate and Extyrageniculate Paths (SC -> RF, abstract)] ||
|| [BrainAreaNDM NDM] || [BrainRegionNDM_NC_AL_VACG NDM.NC.AL.VACG] || Ventral Anterior Cingulate Area || excitatory-glu || uncertain ||[http://openagrosrl.com/www/page/292/ Motor neurons control (CTX -> PRF, abstract)] ||
|| [BrainAreaNMA NMA] || [BrainRegionNMA_NC_MC NMA.NC.MC] || Motor Cortex || excitatory-glu || uncertain ||[http://openagrosrl.com/www/page/292/ Motor neurons control (CTX -> PRF, abstract)] ||
||  || [BrainRegionNMA_NC_SMC_F3 NMA.NC.SMC.F3] || Supplementary Motor Area || excitatory-glu || uncertain ||[http://openagrosrl.com/www/page/292/ Motor neurons control (CTX -> PRF, abstract)] ||
|| [BrainAreaNPE NPE] || [BrainRegionNPE_NC_BRA_PO NPE.NC.BRA.PO] || Broca's Area Pars Opercularis || excitatory-glu || uncertain ||[http://openagrosrl.com/www/page/292/ Motor neurons control (CTX -> PRF, abstract)] ||

*Outbound Region Connections:*

|| *Target Area* || *Target Region* || *Target Name* || *Type* || *Role* || *Reference* ||
|| [BrainAreaLRC LRC] || [BrainRegionLRC_HT_CR_FN LRC.HT.CR.FN] || Cerebellar Flocconodular Lobe || inhibitory-gaba || uncertain || (unknown reference) ||
||  || [BrainRegionLRC_HT_CR_VM LRC.HT.CR.VM] || Cerebellar Vermis || inhibitory-gaba || uncertain || (unknown reference) ||

= Thirdparty Circuits =
(generated)

  * [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/mb.jpg Mammillary Body] (unknown reference) (CT.LMB-MMB)

 LMB=[BrainRegionFMM_FD_MB_LMB Lateral Mammillary Nucleus,FMM.FD.MB.LMB]
 MMB=[BrainRegionFMM_FD_MB_MMB Medial Mammillary Nucleus,FMM.FD.MB.MMB]
 RTG=[BrainRegionLLC_HT_PRF_RTMG Pontine Reticulotegmental Nucleus,LLC.HT.PRF.RTMG]
<img src="http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/mb.jpg" alt="unavailable" style="max-width: 100%;">

  * [http://ars.els-cdn.com/content/image/1-s2.0-S0006899301025987-gr1.gif Horizontal saccades and smooth pursuit movements] - see [http://www.sciencedirect.com/science/article/pii/S0006899301025987 Reference] (CP.VISION-SACCADES)

 Bechterew=[BrainRegionLLC_HT_PRF_RTMG Pontine Reticulotegmental Nucleus,LLC.HT.PRF.RTMG]
 CR=Cerebellum,LLC.HT.CR (see [BrainCenterLLC_HT_CRC Cerebellar Complex])
 FEFSEF=Anterior Lobe,NC.LOBE.ANT
 LGB=[BrainRegionNSA_FD_LGN Lateral Geniculate Nucleus,NSA.FD.LGN]
 PPRF=Paramedian Pontine Reticular Formation,HT.PRF.PPRF (see [BrainCenterHT_RF Pontine Reticular Formation])
 PrimaryVisual=[BrainRegionNSA_NC_OCC_V1 Primary Visual Cortex,NSA.NC.OCC.V1]
 RIP=[BrainRegionLRC_MM_RP_RIP Raphe Interpositus Nucleus,LRC.MM.RP.RIP]
 SC=Superior Colliculus,MM.SC (see [BrainCenterMM_REF Reflexes Nuclei of Midbrain Mesencephalon])
 Striatum=Striatum,FEC.FT.ST (see [BrainCenterFEC_FT_BG Basal Ganglia])
 Vestibular=[BrainRegionLPC_HT_SVBN Superior Vestibular Nucleus,LPC.HT.SVBN]
 VisualAssociation=[BrainRegionNPE_NC_SPL_PG Caudal Precuneus,NPE.NC.SPL.PG]
<img src="http://ars.els-cdn.com/content/image/1-s2.0-S0006899301025987-gr1.gif" alt="unavailable" style="max-width: 100%;">


= References =
(generated)

  * http://www.sciencedirect.com/science/article/pii/S0006899301025987