#summary Edinger-Westphal Nucleus @@[Home] -> [BiologicalLifeResearch] -> [BrainAreaLAC] -> [BrainRegionLAC_MM_EWN] ---- This page covers biological details of component Edinger-Westphal Nucleus. Region is part of aHuman target integrated biological model. * *Top-down path to region*: Midbrain Mesencephalon -> [BrainCenterMM_PER Perhipheral Nuclei of Midbrain Mesencephalon] (MM.PER) -> [BrainRegionLAC_MM_EWN Edinger-Westphal Nucleus] (LAC.MM.EWN) (see [OverallMindMaps Mind Maps]) * *Type*: nucleus * *Quality*: L0 * *Brain area*: [BrainAreaLAC Lower Brain - Autonomous Control Area] (LAC) * *Area circuit*: Vision Autonomic Control (LAV) * *Role*: parasympathetic.nucleus * *Function*: Change Eye Pupil * *Notes to function*: * Parasympathetic nucleus, parvocellular extention of OCN (generated) = Components = (generated) * no child items defined = Connectivity = (generated) http://ahuman.org/svn/ahwiki/images/dot/LAC.MM.EWN.dot.png *Inbound Region Connections:* || *Source Area* || *Source Region* || *Source Name* || *Type* || *Role* || *Reference* || || [BrainAreaLRC LRC] || [BrainRegionLRC_MM_DSCH LRC.MM.DSCH] || Darkschewitsch Nucleus || excitatory-glu || uncertain ||[http://neuroscience.uth.tmc.edu/s3/chapter07.html Eye blink reflex and pupillary light reflex (SupraOculomotor -> EWN, abstract)] || || || [BrainRegionLRC_MM_PT_PON LRC.MM.PT.PON] || Pretectal Olivary Nucleus || excitatory-glu || uncertain ||[http://journal.frontiersin.org/article/10.3389/fnint.2012.00094/full Effect of light on pupil diameter (OPN -> EW)] || || || [BrainRegionLRC_MM_PT_PR LRC.MM.PT.PR] || Principal Pretectal Nucleus || excitatory-glu || uncertain ||[http://neuroscience.uth.tmc.edu/s3/chapter07.html Eye blink reflex and pupillary light reflex (Pretectum -> EWN, abstract)] || || || [BrainRegionLRC_MM_PT_SL LRC.MM.PT.SL] || Sublentiform Nucleus || excitatory-glu || uncertain ||[http://neuroscience.uth.tmc.edu/s3/chapter07.html Eye blink reflex and pupillary light reflex (Pretectum -> EWN, abstract)] || *Outbound Region Connections:* || *Target Area* || *Target Region* || *Target Name* || *Type* || *Role* || *Reference* || || [BrainAreaLAC LAC] || [BrainRegionLAC_PN_PSYM_CLG LAC.PN.PSYM.CLG] || Ciliary Ganglion || excitatory-glu || uncertain || [http://www.neurophysiology.ws/autonomicns.htm Autonomic nervous system (EWN -> CLG)] || || || [BrainRegionLAC_PN_PSYM_EPG LAC.PN.PSYM.EPG] || Episcleral Ganglion || excitatory-glu || uncertain || [http://www.neurophysiology.ws/autonomicns.htm Autonomic nervous system (EWN -> EPG)] || = Thirdparty Circuits = (generated) * [http://www.neurophysiology.ws/images/fig-4.gif Autonomic nervous system] - see [http://www.neurophysiology.ws/autonomicns.htm Reference] (CM.AUTONOMIC-MUSCLES) CLG=[BrainRegionLAC_PN_PSYM_CLG Ciliary Ganglion,LAC.PN.PSYM.CLG] DM=[BrainRegionLAC_HL_VGN Vagus Nucleus,LAC.HL.VGN] EPG=[BrainRegionLAC_PN_PSYM_EPG Episcleral Ganglion,LAC.PN.PSYM.EPG] EWN=[BrainRegionLAC_MM_EWN Edinger-Westphal Nucleus,LAC.MM.EWN] EYE=[BrainRegionTARGET_TSA_EYE Eye,TARGET.TSA.EYE] ISL=[BrainRegionLAC_HL_SAL_ISL Inferior Salivatory Nucleus,LAC.HL.SAL.ISL] OTG=[BrainRegionLAC_PN_PSYM_OTG Otic Ganglion,LAC.PN.PSYM.OTG] SMG=[BrainRegionLAC_PN_PSYM_SXG Submandibular Ganglion,LAC.PN.PSYM.SXG] SPG=[BrainRegionLAC_PN_PSYM_SPG Sphenopalatine Ganglion,LAC.PN.PSYM.SPG] SSL=[BrainRegionLAC_HL_SAL_SSL Superior Salivatory Nucleus,LAC.HL.SAL.SSL] unavailable * [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/vision-subcortical.jpg Vision Components] - see [http://neuroscience.uth.tmc.edu/s3/chapter07.html Reference] (CP.VISION-COMPONENTS) CG=[BrainRegionLAC_PN_PSYM_CLG Ciliary Ganglion,LAC.PN.PSYM.CLG] EWN=[BrainRegionLAC_MM_EWN Edinger-Westphal Nucleus,LAC.MM.EWN] EYE=[BrainRegionTARGET_TSA_EYE Eye,TARGET.TSA.EYE] LGN=[BrainRegionNSA_FD_LGN Lateral Geniculate Nucleus,NSA.FD.LGN] OCN=[BrainRegionLPC_MM_OCN Oculomotor Nucleus,LPC.MM.OCN] RT=[BrainRegionLPC_PN_SG_RT Retinal Ganglion,LPC.PN.SG.RT] SOA=Supraoculomotor Area,VBA.MM.SOA (see [BrainCenterMM_REF Reflexes Nuclei of Midbrain Mesencephalon]) STN=[BrainRegionLPC_HL_TGS_STR Spinal Trigeminal Nucleus,LPC.HL.TGS.STR] VAC=Posterior Eye Field,NPE.NC.IPS.PEF (see [BrainCenterNSA_NC_IPS Intraparietal Sulcus]) VC=[BrainCenterNC_LOBE_OCC Occipital Lobe,NC.LOBE.OCC] unavailable * [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/oculomotor.jpg Eye blink reflex and pupillary light reflex] - see [http://neuroscience.uth.tmc.edu/s3/chapter07.html Reference] (CP.SACCADIC-MOTOR-CONTROL) Abducens=[BrainRegionLPC_HT_ABD Abducens Nucleus,LPC.HT.ABD] Ciliary=[BrainRegionLAC_PN_PSYM_CLG Ciliary Ganglion,LAC.PN.PSYM.CLG] EWN=[BrainRegionLAC_MM_EWN Edinger-Westphal Nucleus,LAC.MM.EWN] EYE=[BrainRegionTARGET_TSA_EYE Eye,TARGET.TSA.EYE] Facial=[BrainRegionLPC_HT_FCM Facial Motor Nucleus,LPC.HT.FCM] Oculomotor=[BrainRegionLPC_MM_OCN Oculomotor Nucleus,LPC.MM.OCN] Pretectum=Pretectum,MM.PT (see [BrainCenterMM_REF Reflexes Nuclei of Midbrain Mesencephalon]) PrincipalTrigeminal=[BrainRegionLPC_HT_PN_PTR Principal Trigeminal Nucleus,LPC.HT.PN.PTR] RF=[BrainCenterHT_RF Pontine Reticular Formation,HT.RF] SpinalTrigeminal=[BrainRegionLPC_HL_TGS_STR Spinal Trigeminal Nucleus,LPC.HL.TGS.STR] SupraOculomotor=Supraoculomotor Area,VBA.MM.SOA (see [BrainCenterMM_REF Reflexes Nuclei of Midbrain Mesencephalon]) VAC=Associative Visual Cortex,NPE.NC.OCC.V3 (see [BrainCenterNC_LOBE_OCC Occipital Lobe]) unavailable * [http://www.frontiersin.org/files/Articles/31465/fnint-06-00094-r2/image_m/fnint-06-00094-g002.jpg Effect of light on pupil diameter] - see [http://journal.frontiersin.org/article/10.3389/fnint.2012.00094/full Reference] (CP.PUPIL-REFLEX) DMH=[BrainRegionLAC_FD_HT_DM Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM] EW=[BrainRegionLAC_MM_EWN Edinger-Westphal Nucleus,LAC.MM.EWN] EYE=[BrainRegionTARGET_TSA_EYE Eye,TARGET.TSA.EYE] GC=[BrainRegionLAC_PN_PSYM_CLG Ciliary Ganglion,LAC.PN.PSYM.CLG] IML=[BrainRegionLAC_SC_IZ_CSC Ciliospinal Center,LAC.SC.IZ.CSC] LC=[BrainRegionLMC_HT_LC Locus Coeruleus,LMC.HT.LC] OPN=[BrainRegionLRC_MM_PT_PON Pretectal Olivary Nucleus,LRC.MM.PT.PON] PVN=[BrainRegionLAC_FD_HT_PV Paraventricular Nucleus,LAC.FD.HT.PV] RET=[BrainRegionLPC_FD_RT Retinal Nucleus,LPC.FD.RT] SCG=[BrainRegionLAC_PN_SYM_SCG Superior Cervical Ganglion,LAC.PN.SYM.SCG] SCN=[BrainRegionLAC_FD_HT_SCN Suprachiasmatic Nucleus,LAC.FD.HT.SCN] unavailable * [http://www.nature.com/pr/journal/v71/n3/images/pr201138f1.gif Sympathetic and parasympathetic eye pathways] - see [http://www.nature.com/pr/journal/v71/n3/fig_tab/pr201138f1.html Reference] (CP.EYE-SYM-PATHWAYS) CC=[BrainRegionLAC_SC_IZ_CSC Ciliospinal Center,LAC.SC.IZ.CSC] CLG=[BrainRegionLAC_PN_PSYM_CLG Ciliary Ganglion,LAC.PN.PSYM.CLG] EWN=[BrainRegionLAC_MM_EWN Edinger-Westphal Nucleus,LAC.MM.EWN] EYE=[BrainRegionTARGET_TSA_EYE Eye,TARGET.TSA.EYE] PHT=[BrainRegionLAC_FD_HT_PN Posterior Hypothalamic Nucleus,LAC.FD.HT.PN] SCG=[BrainRegionLAC_PN_SYM_SCG Superior Cervical Ganglion,LAC.PN.SYM.SCG] unavailable = References = (generated) * http://www.neurophysiology.ws/autonomicns.htm * http://neuroscience.uth.tmc.edu/s3/chapter07.html * http://journal.frontiersin.org/article/10.3389/fnint.2012.00094/full * http://www.nature.com/pr/journal/v71/n3/fig_tab/pr201138f1.html