#summary Ventromedial Hypothalamic Nucleus @@[Home] -> [BiologicalLifeResearch] -> [BrainAreaLAC] -> [BrainRegionLAC_FD_HT_VM] ---- This page covers biological details of component Ventromedial Hypothalamic Nucleus. Region is part of aHuman target integrated biological model. * *Top-down path to region*: Forebrain Diencephalon -> [BrainCenterFD_HT Hypothalamus] (FD.HT) -> Anterior Hypothalamus Area (LAC.FD.HT.AHT) -> Tuberal Area (LAC.FD.HT.TUB) -> [BrainRegionLAC_FD_HT_VM Ventromedial Hypothalamic Nucleus] (LAC.FD.HT.VM) (see [OverallMindMaps Mind Maps]) * *Type*: nucleus * *Quality*: L0 * *Brain area*: [BrainAreaLAC Lower Brain - Autonomous Control Area] (LAC) * *Area circuit*: Thirst and Hunger Control (LATH) * *Role*: processor.autonomic * *Function*: Satiety, control of eating * *Notes to function*: * medial of tuberculum (generated) = Components = (generated) * no child items defined = Connectivity = (generated) http://ahuman.org/svn/ahwiki/images/dot/LAC.FD.HT.VM.dot.png *Inbound Region Connections:* || *Source Area* || *Source Region* || *Source Name* || *Type* || *Role* || *Reference* || || [BrainAreaFAM FAM] || [BrainRegionFAM_FT_AM_MPV FAM.FT.AM.MPV] || Medial Posterior Ventral Amygdaloid Nucleus || inhibitory-gaba || uncertain ||[http://www.pnas.org/content/107/40/17071/F1.expansion.html Role for serotonin in moral behavior (AMY -> HYP, abstract)] || || [BrainAreaFMM FMM] || [BrainRegionFMM_FT_HF_SUBP FMM.FT.HF.SUBP] || Proximal Subiculum || excitatory-glu || uncertain ||(unknown reference) || || [BrainAreaLAC LAC] || [BrainRegionLAC_FD_HT_AH LAC.FD.HT.AH] || Anterior Hypothalamic Nucleus || excitatory-glu || uncertain ||[http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf Intrahypothalamic connections important for neural control of food intake and energy balance (AH -> VMN)] || || || [BrainRegionLAC_FD_HT_AR LAC.FD.HT.AR] || Arcuate Nucleus of Hypothalamus || excitatory-glu || uncertain ||[http://neuroscience.uth.tmc.edu/s4/chapter04.html Schematic of hypothalamic circuitry underlying satiety (ARC -> VMH)] || || || [BrainRegionLAC_FD_HT_PRM LAC.FD.HT.PRM] || Premammillary Nucleus || excitatory-glu || uncertain ||(unknown reference) || *Outbound Region Connections:* || *Target Area* || *Target Region* || *Target Name* || *Type* || *Role* || *Reference* || || [BrainAreaFAM FAM] || [BrainRegionFAM_FT_BNST FAM.FT.BNST] || Bed Nucleus of Stria Terminalis || excitatory-glu || uncertain || (unknown reference) || || [BrainAreaFEC FEC] || [BrainRegionFEC_FD_STN_CD FEC.FD.STN.CD] || Subthalamic Nucleus Caudal || excitatory-glu || uncertain || (unknown reference) || || || [BrainRegionFEC_FT_ACC_SH FEC.FT.ACC.SH] || Nucleus Accumbens Shell || excitatory-glu || uncertain || [http://www.nature.com/nrendo/journal/v6/n8/fig_tab/nrendo.2010.93_F1.html Bowels control brain: gut hormones and obesity (VMN -> NAc, abstract)] || || [BrainAreaLAC LAC] || [BrainRegionLAC_FD_HT_DM LAC.FD.HT.DM] || Dorsomedial Hypothalamic Nucleus || excitatory-glu || uncertain || [http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf Intrahypothalamic connections important for neural control of food intake and energy balance (VMN -> DMN)] || || || [BrainRegionLAC_FD_HT_LTN LAC.FD.HT.LTN] || Lateral Hypothalamic Nucleus || excitatory-glu || uncertain || [http://ajpregu.physiology.org/content/302/2/R215 Glucose-sensing neural network (VMH -> LHA)] || || || [BrainRegionLAC_FD_HT_PV LAC.FD.HT.PV] || Paraventricular Nucleus || excitatory-glu || uncertain || [http://ajpregu.physiology.org/content/302/2/R215 Glucose-sensing neural network (VMH -> PVH)] || || || [BrainRegionLAC_FD_HT_VLPO LAC.FD.HT.VLPO] || Ventrolateral Preoptic Nucleus || excitatory-glu || uncertain || (unknown reference) || || [BrainAreaLPC LPC] || [BrainRegionLPC_HL_SOL LPC.HL.SOL] || Solitary Nucleus || excitatory-glu || uncertain || [http://www.nature.com/nrendo/journal/v6/n8/fig_tab/nrendo.2010.93_F1.html Bowels control brain: gut hormones and obesity (VMN -> NTS)] || = Thirdparty Circuits = (generated) * [http://dkqlgfb5sk2dk.cloudfront.net/content/ajpregu/302/2/R215/F1.large.jpg Glucose-sensing neural network] - see [http://ajpregu.physiology.org/content/302/2/R215 Reference] (CP.GLUCOSE) ARC=[BrainRegionLAC_FD_HT_AR Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR] DMN=[BrainRegionLAC_FD_HT_DM Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM] LHA=[BrainRegionLAC_FD_HT_LTN Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN] PVH=[BrainRegionLAC_FD_HT_PV Paraventricular Nucleus,LAC.FD.HT.PV] VMH=[BrainRegionLAC_FD_HT_VM Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM] unavailable * [http://www.nature.com/nrendo/journal/v6/n8/images/nrendo.2010.93-f1.jpg Bowels control brain: gut hormones and obesity] - see [http://www.nature.com/nrendo/journal/v6/n8/fig_tab/nrendo.2010.93_F1.html Reference] (CP.BOWELS) AMY=[BrainCenterFAM_FT_AM Amygdala,FAM.FT.AM] ARC=[BrainRegionLAC_FD_HT_AR Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR] DS=Dorsal Striatum,FEC.FT.DST (see [BrainCenterFEC_FT_BG Basal Ganglia]) LHA=[BrainRegionLAC_FD_HT_LTN Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN] ME=[BrainRegionTARGET_TEA_ENDOCRINE Endocrine Glands,TARGET.TEA.ENDOCRINE] NAc=Accumbens Nucleus,FEC.FT.ACC (see [BrainCenterFEC_FT_BG Basal Ganglia]) NTS=[BrainRegionLPC_HL_SOL Solitary Nucleus,LPC.HL.SOL] OFC=Orbitofrontal Cortex,NC.AL.OPFC (see [BrainCenterNC_AL_OMPFC Orbitomedial Prefrontal Cortex]) PBN=[BrainRegionLPC_HT_PRF_PB Parabrachial Nucleus,LPC.HT.PRF.PB] PVN=[BrainRegionLAC_FD_HT_PV Paraventricular Nucleus,LAC.FD.HT.PV] VMN=[BrainRegionLAC_FD_HT_VM Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM] VTA=[BrainRegionLMC_MM_VTA Ventral Tegmental Area,LMC.MM.VTA] unavailable * [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/intrahypothalamic.png Intrahypothalamic connections important for neural control of food intake and energy balance] - see [http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf Reference] (CL.INTRAHYPOTHALAMIC) AH=[BrainRegionLAC_FD_HT_AH Anterior Hypothalamic Nucleus,LAC.FD.HT.AH] ARC=[BrainRegionLAC_FD_HT_AR Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR] DMN=[BrainRegionLAC_FD_HT_DM Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM] LHA=[BrainRegionLAC_FD_HT_LTN Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN] MPOA=[BrainRegionLAC_FD_HT_MPO Median Preoptic Nucleus,LAC.FD.HT.MPO] PA=[BrainRegionLAC_FD_HT_PV Paraventricular Nucleus,LAC.FD.HT.PV] SCH=[BrainRegionLAC_FD_HT_SCN Suprachiasmatic Nucleus,LAC.FD.HT.SCN] SON=[BrainRegionLAC_FD_HT_SO Supraoptic Nucleus,LAC.FD.HT.SO] VMN=[BrainRegionLAC_FD_HT_VM Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM] unavailable * [http://neuroscience.uth.tmc.edu/s4/images/dougherty/pdougherty4_3.jpg Schematic of hypothalamic circuitry underlying satiety] - see [http://neuroscience.uth.tmc.edu/s4/chapter04.html Reference] (CP.SATIETY) ARC=[BrainRegionLAC_FD_HT_AR Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR] DMH=[BrainRegionLAC_FD_HT_DM Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM] LHA=[BrainRegionLAC_FD_HT_LTN Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN] NTS=[BrainRegionLPC_HL_SOL Solitary Nucleus,LPC.HL.SOL] PVN=[BrainRegionLAC_FD_HT_PV Paraventricular Nucleus,LAC.FD.HT.PV] VMH=[BrainRegionLAC_FD_HT_VM Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM] unavailable * [http://www.dana.org/uploadedImages/Images/Content_Images/SenBodyFunc2_PR2007_cont.jpg Eating and sleeping to survive] - see [http://www.dana.org/Publications/ReportDetails.aspx?id=44217 Reference] (CP.DMH-CYCLES) ARC=[BrainRegionLAC_FD_HT_AR Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR] DMH=[BrainRegionLAC_FD_HT_DM Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM] LHA=[BrainRegionLAC_FD_HT_LTN Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN] MPO=[BrainRegionLAC_FD_HT_MPO Median Preoptic Nucleus,LAC.FD.HT.MPO] PVH=[BrainRegionLAC_FD_HT_PV Paraventricular Nucleus,LAC.FD.HT.PV] SCN=[BrainRegionLAC_FD_HT_SCN Suprachiasmatic Nucleus,LAC.FD.HT.SCN] VLPO=[BrainRegionLAC_FD_HT_VLPO Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO] VMH=[BrainRegionLAC_FD_HT_VM Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM] unavailable * [http://www.jneurosci.org/content/20/4/1589/F9.medium.gif Spine induction on short primary dendrites in the ventrolateral VMH] - see [http://www.jneurosci.org/content/20/4/1589/F9.expansion Reference] (CL.VMH-PAG) PAG=[BrainRegionLMC_MM_PAG Periaqueductal Gray Matter,LMC.MM.PAG] VMH=[BrainRegionLAC_FD_HT_VM Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM] unavailable = References = (generated) * http://ajpregu.physiology.org/content/302/2/R215 * http://www.nature.com/nrendo/journal/v6/n8/fig_tab/nrendo.2010.93_F1.html * http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf * http://neuroscience.uth.tmc.edu/s4/chapter04.html * http://www.dana.org/Publications/ReportDetails.aspx?id=44217 * http://www.jneurosci.org/content/20/4/1589/F9.expansion