#summary Suprachiasmatic Nucleus @@[Home] -> [BiologicalLifeResearch] -> [BrainAreaLAC] -> [BrainRegionLAC_FD_HT_SCN] ---- This page covers biological details of component Suprachiasmatic Nucleus. Region is part of aHuman target integrated biological model. * *Top-down path to region*: Forebrain Diencephalon -> [BrainCenterFD_HT Hypothalamus] (FD.HT) -> Anterior Hypothalamus Area (LAC.FD.HT.AHT) -> Chiasmatic Area (LAC.FD.HT.CHS) -> [BrainRegionLAC_FD_HT_SCN Suprachiasmatic Nucleus] (LAC.FD.HT.SCN) (see [OverallMindMaps Mind Maps]) * *Type*: nucleus * *Quality*: L0 * *Brain area*: [BrainAreaLAC Lower Brain - Autonomous Control Area] (LAC) * *Area circuit*: Daily Cycle Autonomic Control (LADC) * *Role*: processor.autonomic * *Function*: Regulate the circadian cycle, 24-hour rhythms (generated) = Components = (generated) *Component items*: * *Dorsomedial Suprachiasmatic Nucleus* * *Ventrolateral Suprachiasmatic Nucleus* * *Ventral Suprachiasmatic Nucleus* = Connectivity = (generated) http://ahuman.org/svn/ahwiki/images/dot/LAC.FD.HT.SCN.dot.png *Inbound Region Connections:* || *Source Area* || *Source Region* || *Source Name* || *Type* || *Role* || *Reference* || || [BrainAreaLPC LPC] || [BrainRegionLPC_FD_RT LPC.FD.RT] || Retinal Nucleus || excitatory-glu || uncertain ||[http://journal.frontiersin.org/article/10.3389/fnint.2012.00094/full Effect of light on pupil diameter (RET -> SCN)] || || [BrainAreaNDM NDM] || [BrainRegionNDM_FD_TH_PV NDM.FD.TH.PV] || Paraventricular Nucleus of Thalamus || excitatory-glu || uncertain ||(unknown reference) || *Outbound Region Connections:* || *Target Area* || *Target Region* || *Target Name* || *Type* || *Role* || *Reference* || || [BrainAreaLAC LAC] || [BrainRegionLAC_FD_HT_DM LAC.FD.HT.DM] || Dorsomedial Hypothalamic Nucleus || excitatory-glu || uncertain || [http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf Intrahypothalamic connections important for neural control of food intake and energy balance (SCH -> DMN)] || || || [BrainRegionLAC_FD_HT_MPO LAC.FD.HT.MPO] || Median Preoptic Nucleus || excitatory-glu || uncertain || [http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf Intrahypothalamic connections important for neural control of food intake and energy balance (SCH -> MPOA)] || || || [BrainRegionLAC_FD_HT_PV LAC.FD.HT.PV] || Paraventricular Nucleus || excitatory-glu || uncertain || [http://www.pnas.org/content/103/32/12150/F7.expansion.html Food-entrainable circadian oscillator (SCN -> PVH)] || || || [BrainRegionLAC_FD_HT_VLPO LAC.FD.HT.VLPO] || Ventrolateral Preoptic Nucleus || excitatory-glu || uncertain || (unknown reference) || || [BrainAreaLRC LRC] || [BrainRegionLRC_MM_PT_NOT LRC.MM.PT.NOT] || Nucleus of Optic Tract || excitatory-glu || uncertain || (unknown reference) || = Thirdparty Circuits = (generated) * [http://www.pnas.org/content/103/32/12150/F7.large.jpg Food-entrainable circadian oscillator] - see [http://www.pnas.org/content/103/32/12150/F7.expansion.html Reference] (CP.FOOD-OCSILLATOR) DMH=[BrainRegionLAC_FD_HT_DM Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM] LH=[BrainRegionLAC_FD_HT_LTN Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN] NTS=[BrainRegionLPC_HL_SOL Solitary Nucleus,LPC.HL.SOL] PBN=[BrainRegionLPC_HT_PRF_PB Parabrachial Nucleus,LPC.HT.PRF.PB] PVH=[BrainRegionLAC_FD_HT_PV Paraventricular Nucleus,LAC.FD.HT.PV] SCN=[BrainRegionLAC_FD_HT_SCN Suprachiasmatic Nucleus,LAC.FD.HT.SCN] unavailable * [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/intrahypothalamic.png Intrahypothalamic connections important for neural control of food intake and energy balance] - see [http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf Reference] (CL.INTRAHYPOTHALAMIC) AH=[BrainRegionLAC_FD_HT_AH Anterior Hypothalamic Nucleus,LAC.FD.HT.AH] ARC=[BrainRegionLAC_FD_HT_AR Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR] DMN=[BrainRegionLAC_FD_HT_DM Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM] LHA=[BrainRegionLAC_FD_HT_LTN Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN] MPOA=[BrainRegionLAC_FD_HT_MPO Median Preoptic Nucleus,LAC.FD.HT.MPO] PA=[BrainRegionLAC_FD_HT_PV Paraventricular Nucleus,LAC.FD.HT.PV] SCH=[BrainRegionLAC_FD_HT_SCN Suprachiasmatic Nucleus,LAC.FD.HT.SCN] SON=[BrainRegionLAC_FD_HT_SO Supraoptic Nucleus,LAC.FD.HT.SO] VMN=[BrainRegionLAC_FD_HT_VM Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM] unavailable * [http://www.frontiersin.org/files/Articles/31465/fnint-06-00094-r2/image_m/fnint-06-00094-g002.jpg Effect of light on pupil diameter] - see [http://journal.frontiersin.org/article/10.3389/fnint.2012.00094/full Reference] (CP.PUPIL-REFLEX) DMH=[BrainRegionLAC_FD_HT_DM Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM] EW=[BrainRegionLAC_MM_EWN Edinger-Westphal Nucleus,LAC.MM.EWN] EYE=[BrainRegionTARGET_TSA_EYE Eye,TARGET.TSA.EYE] GC=[BrainRegionLAC_PN_PSYM_CLG Ciliary Ganglion,LAC.PN.PSYM.CLG] IML=[BrainRegionLAC_SC_IZ_CSC Ciliospinal Center,LAC.SC.IZ.CSC] LC=[BrainRegionLMC_HT_LC Locus Coeruleus,LMC.HT.LC] OPN=[BrainRegionLRC_MM_PT_PON Pretectal Olivary Nucleus,LRC.MM.PT.PON] PVN=[BrainRegionLAC_FD_HT_PV Paraventricular Nucleus,LAC.FD.HT.PV] RET=[BrainRegionLPC_FD_RT Retinal Nucleus,LPC.FD.RT] SCG=[BrainRegionLAC_PN_SYM_SCG Superior Cervical Ganglion,LAC.PN.SYM.SCG] SCN=[BrainRegionLAC_FD_HT_SCN Suprachiasmatic Nucleus,LAC.FD.HT.SCN] unavailable * [http://www.dana.org/uploadedImages/Images/Content_Images/SenBodyFunc2_PR2007_cont.jpg Eating and sleeping to survive] - see [http://www.dana.org/Publications/ReportDetails.aspx?id=44217 Reference] (CP.DMH-CYCLES) ARC=[BrainRegionLAC_FD_HT_AR Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR] DMH=[BrainRegionLAC_FD_HT_DM Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM] LHA=[BrainRegionLAC_FD_HT_LTN Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN] MPO=[BrainRegionLAC_FD_HT_MPO Median Preoptic Nucleus,LAC.FD.HT.MPO] PVH=[BrainRegionLAC_FD_HT_PV Paraventricular Nucleus,LAC.FD.HT.PV] SCN=[BrainRegionLAC_FD_HT_SCN Suprachiasmatic Nucleus,LAC.FD.HT.SCN] VLPO=[BrainRegionLAC_FD_HT_VLPO Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO] VMH=[BrainRegionLAC_FD_HT_VM Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM] unavailable = References = (generated) * http://www.pnas.org/content/103/32/12150/F7.expansion.html * http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf * http://journal.frontiersin.org/article/10.3389/fnint.2012.00094/full * http://www.dana.org/Publications/ReportDetails.aspx?id=44217