#summary Median Preoptic Nucleus
@@[Home] -> [BiologicalLifeResearch] -> [BrainAreaLAC] -> [BrainRegionLAC_FD_HT_MPO]
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This page covers biological details of component Median Preoptic Nucleus.
Region is part of aHuman target integrated biological model.
* *Top-down path to region*: Forebrain Diencephalon -> [BrainCenterFD_HT Hypothalamus] (FD.HT) -> Anterior Hypothalamus Area (LAC.FD.HT.AHT) -> Chiasmatic Area (LAC.FD.HT.CHS) -> Preoptic Nucleus (LAC.FD.HT.PO) -> [BrainRegionLAC_FD_HT_MPO Median Preoptic Nucleus] (LAC.FD.HT.MPO) (see [OverallMindMaps Mind Maps])
* *Type*: nucleus
* *Quality*: L0
* *Brain area*: [BrainAreaLAC Lower Brain - Autonomous Control Area] (LAC)
* *Area circuit*: Autonomic Thermoregulation (LAT)
* *Role*: processor.autonomic
* *Function*: generates thirst
* *Notes to function*:
* Drinking decreases noradrenaline release in median preoptic nucleus
(generated)
= Components =
(generated)
* no child items defined
= Connectivity =
(generated)
http://ahuman.org/svn/ahwiki/images/dot/LAC.FD.HT.MPO.dot.png
*Inbound Region Connections:*
|| *Source Area* || *Source Region* || *Source Name* || *Type* || *Role* || *Reference* ||
|| [BrainAreaFAM FAM] || [BrainRegionFAM_FT_AM_MPD FAM.FT.AM.MPD] || Medial Posterior Dorsal Amygdaloid Nucleus || inhibitory-gaba || uncertain ||[http://www.pnas.org/content/107/40/17071/F1.expansion.html Role for serotonin in moral behavior (AMY -> HYP, abstract)] ||
|| [BrainAreaFMM FMM] || [BrainRegionFMM_FT_HC_CA1D FMM.FT.HC.CA1D] || Distal CA1 of Hippocampus || excitatory-glu || uncertain ||[http://www.nature.com/nrn/journal/v5/n7 Feeling (HC -> HT, abstract)] ||
|| [BrainAreaLAC LAC] || [BrainRegionLAC_FD_HT_DM LAC.FD.HT.DM] || Dorsomedial Hypothalamic Nucleus || excitatory-glu || uncertain ||[http://www.dana.org/Publications/ReportDetails.aspx?id=44217 Eating and sleeping to survive (DMH -> MPO)] ||
|| || [BrainRegionLAC_FD_HT_PRM LAC.FD.HT.PRM] || Premammillary Nucleus || excitatory-glu || uncertain ||(unknown reference) ||
|| || [BrainRegionLAC_FD_HT_SCN LAC.FD.HT.SCN] || Suprachiasmatic Nucleus || excitatory-glu || uncertain ||[http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf Intrahypothalamic connections important for neural control of food intake and energy balance (SCH -> MPOA)] ||
|| || [BrainRegionLAC_HL_TGS_PE5 LAC.HL.TGS.PE5] || Peritrigeminal Nucleus || excitatory-glu || uncertain ||(unknown reference) ||
|| [BrainAreaNDM NDM] || [BrainRegionNDM_FD_TH_PV NDM.FD.TH.PV] || Paraventricular Nucleus of Thalamus || excitatory-glu || uncertain ||(unknown reference) ||
*Outbound Region Connections:*
|| *Target Area* || *Target Region* || *Target Name* || *Type* || *Role* || *Reference* ||
|| [BrainAreaFAM FAM] || [BrainRegionFAM_FD_TH_PT FAM.FD.TH.PT] || Paratenial Nucleus of Thalamus || excitatory-glu || uncertain || (unknown reference) ||
|| [BrainAreaLAC LAC] || [BrainRegionLAC_FD_HT_AH LAC.FD.HT.AH] || Anterior Hypothalamic Nucleus || excitatory-glu || uncertain || [http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf Intrahypothalamic connections important for neural control of food intake and energy balance (MPOA -> AH)] ||
|| || [BrainRegionLAC_FD_HT_PV LAC.FD.HT.PV] || Paraventricular Nucleus || excitatory-glu || uncertain || [http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf Intrahypothalamic connections important for neural control of food intake and energy balance (MPOA -> PA)] ||
|| || [BrainRegionLAC_FD_HT_SO LAC.FD.HT.SO] || Supraoptic Nucleus || excitatory-glu || uncertain || [http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf Intrahypothalamic connections important for neural control of food intake and energy balance (MPOA -> SON)] ||
|| [BrainAreaLMC LMC] || [BrainRegionLMC_HL_RP_OB LMC.HL.RP.OB] || Raphe Obscurus Nucleus || excitatory-glu || uncertain || (unknown reference) ||
= Thirdparty Circuits =
(generated)
* [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/intrahypothalamic.png Intrahypothalamic connections important for neural control of food intake and energy balance] - see [http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf Reference] (CL.INTRAHYPOTHALAMIC)
AH=[BrainRegionLAC_FD_HT_AH Anterior Hypothalamic Nucleus,LAC.FD.HT.AH]
ARC=[BrainRegionLAC_FD_HT_AR Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR]
DMN=[BrainRegionLAC_FD_HT_DM Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM]
LHA=[BrainRegionLAC_FD_HT_LTN Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]
MPOA=[BrainRegionLAC_FD_HT_MPO Median Preoptic Nucleus,LAC.FD.HT.MPO]
PA=[BrainRegionLAC_FD_HT_PV Paraventricular Nucleus,LAC.FD.HT.PV]
SCH=[BrainRegionLAC_FD_HT_SCN Suprachiasmatic Nucleus,LAC.FD.HT.SCN]
SON=[BrainRegionLAC_FD_HT_SO Supraoptic Nucleus,LAC.FD.HT.SO]
VMN=[BrainRegionLAC_FD_HT_VM Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM]
* [http://www.dana.org/uploadedImages/Images/Content_Images/SenBodyFunc2_PR2007_cont.jpg Eating and sleeping to survive] - see [http://www.dana.org/Publications/ReportDetails.aspx?id=44217 Reference] (CP.DMH-CYCLES)
ARC=[BrainRegionLAC_FD_HT_AR Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR]
DMH=[BrainRegionLAC_FD_HT_DM Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM]
LHA=[BrainRegionLAC_FD_HT_LTN Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]
MPO=[BrainRegionLAC_FD_HT_MPO Median Preoptic Nucleus,LAC.FD.HT.MPO]
PVH=[BrainRegionLAC_FD_HT_PV Paraventricular Nucleus,LAC.FD.HT.PV]
SCN=[BrainRegionLAC_FD_HT_SCN Suprachiasmatic Nucleus,LAC.FD.HT.SCN]
VLPO=[BrainRegionLAC_FD_HT_VLPO Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO]
VMH=[BrainRegionLAC_FD_HT_VM Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM]
* [http://www.intechopen.com/source/html/40109/media/image1.jpeg Physiology and pathophysiology of lower urinary tract] - see [http://www.intechopen.com/books/computational-intelligence-in-electromyography-analysis-a-perspective-on-current-applications-and-future-challenges/sphincter-emg-for-diagnosing-multiple-system-atrophy-and-related-disorders Reference] (CM.ONUF)
CN=Caudate Nucleus,FEC.FT.CN (see [BrainCenterFEC_FT_BG Basal Ganglia])
DVM=[BrainRegionLAC_HL_VGN Vagus Nucleus,LAC.HL.VGN]
IMG=[BrainRegionLAC_PN_SYM_IMG Inferior Mesenteric Ganglion,LAC.PN.SYM.IMG]
IML=[BrainRegionLAC_SC_IZ_IML Intermediolateral Nucleus,LAC.SC.IZ.IML]
LC=[BrainRegionLMC_HT_LC Locus Coeruleus,LMC.HT.LC]
MPFC=Orbitofrontal Cortex,NC.AL.OPFC (see [BrainCenterNC_AL_OMPFC Orbitomedial Prefrontal Cortex])
MPOA=[BrainRegionLAC_FD_HT_MPO Median Preoptic Nucleus,LAC.FD.HT.MPO]
NBM=[BrainRegionLMC_FT_NBM Basal Nucleus of Meynert,LMC.FT.NBM]
ONF=[BrainRegionLPC_SC_VH_ONF Onuf's Nucleus,LPC.SC.VH.ONF]
PBN=[BrainRegionLPC_HT_PRF_PB Parabrachial Nucleus,LPC.HT.PRF.PB]
PEL=[BrainRegionLAC_PN_PSYM_PPG Pelvic Peripheral Ganglion,LAC.PN.PSYM.PPG]
PU=[BrainRegionFEC_FT_PU_LT Dorsal Putamen Lateral,FEC.FT.PU.LT]
PVN=[BrainRegionLAC_FD_HT_PV Paraventricular Nucleus,LAC.FD.HT.PV]
SNC=[BrainRegionFEC_FT_SNC_LT Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT]
SPS=[BrainRegionLAC_SC_IZ_SPS Sacral Parasympathetic Nucleus,LAC.SC.IZ.SPS]
VTA=[BrainRegionLMC_MM_VTA Ventral Tegmental Area,LMC.MM.VTA]
ZI=[BrainRegionFEC_FD_STN_CD Subthalamic Nucleus Caudal,BGA.FD.STN.ZI]
= References =
(generated)
* http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf
* http://www.dana.org/Publications/ReportDetails.aspx?id=44217
* http://www.intechopen.com/books/computational-intelligence-in-electromyography-analysis-a-perspective-on-current-applications-and-future-challenges/sphincter-emg-for-diagnosing-multiple-system-atrophy-and-related-disorders