#summary Arcuate Nucleus of Hypothalamus
@@[Home] -> [BiologicalLifeResearch] -> [BrainAreaLAC] -> [BrainRegionLAC_FD_HT_AR]
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This page covers biological details of component Arcuate Nucleus of Hypothalamus.
Region is part of aHuman target integrated biological model.
* *Top-down path to region*: Forebrain Diencephalon -> [BrainCenterFD_HT Hypothalamus] (FD.HT) -> Anterior Hypothalamus Area (LAC.FD.HT.AHT) -> Tuberal Area (LAC.FD.HT.TUB) -> [BrainRegionLAC_FD_HT_AR Arcuate Nucleus of Hypothalamus] (LAC.FD.HT.AR) (see [OverallMindMaps Mind Maps])
* *Type*: nucleus
* *Quality*: L0
* *Brain area*: [BrainAreaLAC Lower Brain - Autonomous Control Area] (LAC)
* *Area circuit*: Thirst and Hunger Control (LATH)
* *Role*: processor.autonomic
* *Function*: Regulation of growth, appetite and body weight
* *Notes to function*:
* lateral of tuberlulum, TIDA - releases dopamine to regulate secretion of prolactin hormone, GHRH - stimulate growth hormone secretion (ventrolateral)
(generated)
= Components =
(generated)
* no child items defined
= Connectivity =
(generated)
http://ahuman.org/svn/ahwiki/images/dot/LAC.FD.HT.AR.dot.png
*Inbound Region Connections:*
* no connections
*Outbound Region Connections:*
|| *Target Area* || *Target Region* || *Target Name* || *Type* || *Role* || *Reference* ||
|| [BrainAreaLAC LAC] || [BrainRegionLAC_FD_HT_DM LAC.FD.HT.DM] || Dorsomedial Hypothalamic Nucleus || excitatory-glu || uncertain || [http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf Intrahypothalamic connections important for neural control of food intake and energy balance (ARC -> DMN)] ||
|| || [BrainRegionLAC_FD_HT_LTN LAC.FD.HT.LTN] || Lateral Hypothalamic Nucleus || excitatory-glu || uncertain || [http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf Intrahypothalamic connections important for neural control of food intake and energy balance (ARC -> LHA)] ||
|| || [BrainRegionLAC_FD_HT_PV LAC.FD.HT.PV] || Paraventricular Nucleus || excitatory-glu || uncertain || [http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf Intrahypothalamic connections important for neural control of food intake and energy balance (ARC -> PA)] ||
|| || [BrainRegionLAC_FD_HT_VM LAC.FD.HT.VM] || Ventromedial Hypothalamic Nucleus || excitatory-glu || uncertain || [http://neuroscience.uth.tmc.edu/s4/chapter04.html Schematic of hypothalamic circuitry underlying satiety (ARC -> VMH)] ||
|| [BrainAreaTEA TEA] || [BrainRegionTARGET_TEA_ENDOCRINE TARGET.TEA.ENDOCRINE] || Endocrine Glands || endocrine-adenohypophysis || (none) || (unknown reference) ||
= Thirdparty Circuits =
(generated)
* [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/intrahypothalamic.png Intrahypothalamic connections important for neural control of food intake and energy balance] - see [http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf Reference] (CL.INTRAHYPOTHALAMIC)
AH=[BrainRegionLAC_FD_HT_AH Anterior Hypothalamic Nucleus,LAC.FD.HT.AH]
ARC=[BrainRegionLAC_FD_HT_AR Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR]
DMN=[BrainRegionLAC_FD_HT_DM Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM]
LHA=[BrainRegionLAC_FD_HT_LTN Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]
MPOA=[BrainRegionLAC_FD_HT_MPO Median Preoptic Nucleus,LAC.FD.HT.MPO]
PA=[BrainRegionLAC_FD_HT_PV Paraventricular Nucleus,LAC.FD.HT.PV]
SCH=[BrainRegionLAC_FD_HT_SCN Suprachiasmatic Nucleus,LAC.FD.HT.SCN]
SON=[BrainRegionLAC_FD_HT_SO Supraoptic Nucleus,LAC.FD.HT.SO]
VMN=[BrainRegionLAC_FD_HT_VM Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM]
* [http://neuroscience.uth.tmc.edu/s4/images/dougherty/pdougherty4_3.jpg Schematic of hypothalamic circuitry underlying satiety] - see [http://neuroscience.uth.tmc.edu/s4/chapter04.html Reference] (CP.SATIETY)
ARC=[BrainRegionLAC_FD_HT_AR Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR]
DMH=[BrainRegionLAC_FD_HT_DM Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM]
LHA=[BrainRegionLAC_FD_HT_LTN Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]
NTS=[BrainRegionLPC_HL_SOL Solitary Nucleus,LPC.HL.SOL]
PVN=[BrainRegionLAC_FD_HT_PV Paraventricular Nucleus,LAC.FD.HT.PV]
VMH=[BrainRegionLAC_FD_HT_VM Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM]
* [http://dkqlgfb5sk2dk.cloudfront.net/content/ajpregu/302/2/R215/F1.large.jpg Glucose-sensing neural network] - see [http://ajpregu.physiology.org/content/302/2/R215 Reference] (CP.GLUCOSE)
ARC=[BrainRegionLAC_FD_HT_AR Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR]
DMN=[BrainRegionLAC_FD_HT_DM Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM]
LHA=[BrainRegionLAC_FD_HT_LTN Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]
PVH=[BrainRegionLAC_FD_HT_PV Paraventricular Nucleus,LAC.FD.HT.PV]
VMH=[BrainRegionLAC_FD_HT_VM Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM]
* [http://www.dana.org/uploadedImages/Images/Content_Images/SenBodyFunc2_PR2007_cont.jpg Eating and sleeping to survive] - see [http://www.dana.org/Publications/ReportDetails.aspx?id=44217 Reference] (CP.DMH-CYCLES)
ARC=[BrainRegionLAC_FD_HT_AR Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR]
DMH=[BrainRegionLAC_FD_HT_DM Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM]
LHA=[BrainRegionLAC_FD_HT_LTN Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]
MPO=[BrainRegionLAC_FD_HT_MPO Median Preoptic Nucleus,LAC.FD.HT.MPO]
PVH=[BrainRegionLAC_FD_HT_PV Paraventricular Nucleus,LAC.FD.HT.PV]
SCN=[BrainRegionLAC_FD_HT_SCN Suprachiasmatic Nucleus,LAC.FD.HT.SCN]
VLPO=[BrainRegionLAC_FD_HT_VLPO Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO]
VMH=[BrainRegionLAC_FD_HT_VM Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM]
* [http://www.nature.com/nrendo/journal/v6/n8/images/nrendo.2010.93-f1.jpg Bowels control brain: gut hormones and obesity] - see [http://www.nature.com/nrendo/journal/v6/n8/fig_tab/nrendo.2010.93_F1.html Reference] (CP.BOWELS)
AMY=[BrainCenterFAM_FT_AM Amygdala,FAM.FT.AM]
ARC=[BrainRegionLAC_FD_HT_AR Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR]
DS=Dorsal Striatum,FEC.FT.DST (see [BrainCenterFEC_FT_BG Basal Ganglia])
LHA=[BrainRegionLAC_FD_HT_LTN Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]
ME=[BrainRegionTARGET_TEA_ENDOCRINE Endocrine Glands,TARGET.TEA.ENDOCRINE]
NAc=Accumbens Nucleus,FEC.FT.ACC (see [BrainCenterFEC_FT_BG Basal Ganglia])
NTS=[BrainRegionLPC_HL_SOL Solitary Nucleus,LPC.HL.SOL]
OFC=Orbitofrontal Cortex,NC.AL.OPFC (see [BrainCenterNC_AL_OMPFC Orbitomedial Prefrontal Cortex])
PBN=[BrainRegionLPC_HT_PRF_PB Parabrachial Nucleus,LPC.HT.PRF.PB]
PVN=[BrainRegionLAC_FD_HT_PV Paraventricular Nucleus,LAC.FD.HT.PV]
VMN=[BrainRegionLAC_FD_HT_VM Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM]
VTA=[BrainRegionLMC_MM_VTA Ventral Tegmental Area,LMC.MM.VTA]
= References =
(generated)
* http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf
* http://neuroscience.uth.tmc.edu/s4/chapter04.html
* http://ajpregu.physiology.org/content/302/2/R215
* http://www.dana.org/Publications/ReportDetails.aspx?id=44217
* http://www.nature.com/nrendo/journal/v6/n8/fig_tab/nrendo.2010.93_F1.html