#summary Proximal CA1 of Hippocampus @@[Home] -> [BiologicalLifeResearch] -> [BrainAreaFMM] -> [BrainRegionFMM_FT_HC_CA1P] ---- This page covers biological details of component Proximal CA1 of Hippocampus. Region is part of aHuman target integrated biological model. * *Top-down path to region*: Forebrain Telencephalon -> [BrainCenterFMM_FT_HF Hippocampal Formation] (FMM.FT.HF) -> Hippocampus (FMM.FT.HC) -> Ventrolateral Cornu Ammonis of Hippocampus (FMM.FT.HC.CA1) -> [BrainRegionFMM_FT_HC_CA1P Proximal CA1 of Hippocampus] (FMM.FT.HC.CA1P) (see [OverallMindMaps Mind Maps]) * *Type*: cortex * *Quality*: L0 * *Brain area*: [BrainAreaFMM Forebrain - Memory Management Area] (FMM) * *Area circuit*: Spatial Hippocampus (MMAHCS) * *Role*: processor.memory.ca1 * *Function*: Long-term memory, spatial (generated) = Components = (generated) * no child items defined = Connectivity = (generated) http://ahuman.org/svn/ahwiki/images/dot/FMM.FT.HC.CA1P.dot.png *Inbound Region Connections:* || *Source Area* || *Source Region* || *Source Name* || *Type* || *Role* || *Reference* || || [BrainAreaFAM FAM] || [BrainRegionFAM_FT_AM_AB FAM.FT.AM.AB] || Accessory Basal Amygdaloid Nucleus || excitatory-glu || uncertain ||[https://books.google.ru/books?id=P3fSBwAAQBAJ Detailed amygdalohippocampal projections (ABmg -> CA1P)] || || [BrainAreaFMM FMM] || [BrainRegionFMM_FD_TH_AV FMM.FD.TH.AV] || Anteroventral Nucleus || excitatory-glu || uncertain ||[http://learnmem.cshlp.org/content/18/6/384/F1.expansion.html Contributions of Diencephalon to Recognition Memory (AN -> HC, abstract)] || || || [BrainRegionFMM_FD_TH_LD FMM.FD.TH.LD] || Lateral Dorsal Nucleus of Thalamus || excitatory-glu || uncertain ||[http://learnmem.cshlp.org/content/18/6/384/F1.expansion.html Contributions of Diencephalon to Recognition Memory (LD -> HC, abstract)] || || || [BrainRegionFMM_FT_HC_CA2 FMM.FT.HC.CA2] || Dorsolateral Cornu Ammonis of Hippocampus || excitatory-glu || uncertain ||[http://www.sciencedirect.com/science/article/pii/S030645220600755X Flow of impulses in hippocampal region (CA2 -> CA1, abstract)] || || || [BrainRegionFMM_FT_HC_CA3D FMM.FT.HC.CA3D] || Distal CA3 of Hippocampus || excitatory-glu || uncertain ||[http://journal.frontiersin.org/Journal/10.3389/fpsyt.2013.00061/full Neuronal projections in the hippocampus (CA3 -> CA1, abstract)] || || || [BrainRegionFMM_NC_PH_MEC FMM.NC.PH.MEC] || Medial Entorhinal Cortex || excitatory-glu || uncertain ||[http://journal.frontiersin.org/Journal/10.3389/fpsyt.2013.00061/full Neuronal projections in the hippocampus (ET -> CA1, abstract)] || || [BrainAreaNCP NCP] || [BrainRegionNCP_NC_MPL_PSCG NCP.NC.MPL.PSCG] || Posterior Cingulate Cortex || excitatory-glu || uncertain ||[http://www.nature.com/nrn/journal/v5/n7 Feeling (CG -> HC, abstract)] || || || [BrainRegionNCP_NC_MPL_RSC NCP.NC.MPL.RSC] || Retrosplenial Cortex || excitatory-glu || uncertain ||[https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 Prefrontal Cortex (PFC) in emotional behavior (PCA -> HCA, abstract)] || || [BrainAreaNPE NPE] || [BrainRegionNPE_NC_IPL_MST NPE.NC.IPL.MST] || Medial Superior Temporal Area || excitatory-glu || uncertain ||[http://www.sciencedirect.com/science/article/pii/S0149763409002061 Contribution of hippocampal region CA3 to consciousness (IPL -> CA1, abstract)] || *Outbound Region Connections:* || *Target Area* || *Target Region* || *Target Name* || *Type* || *Role* || *Reference* || || [BrainAreaFMM FMM] || [BrainRegionFMM_FD_MB_MMB FMM.FD.MB.MMB] || Medial Mammillary Nucleus || excitatory-glu || uncertain || [http://www.nature.com/nrn/journal/v5/n7 Feeling (HC -> HT, abstract)] || || || [BrainRegionFMM_FT_HF_SUBD FMM.FT.HF.SUBD] || Distal Subiculum || excitatory-glu || uncertain || [http://learnmem.cshlp.org/content/14/11/714/F1.expansion Attractor Network in Hippocampus (CA1 -> SUB, abstract)] || || || [BrainRegionFMM_NC_PH_PAS FMM.NC.PH.PAS] || Parasubiculum || excitatory-glu || uncertain || (unknown reference) || || || [BrainRegionFMM_NC_PH_POR FMM.NC.PH.POR] || Postrhinal Cortex || excitatory-glu || uncertain || [http://www.sciencedirect.com/science/article/pii/S0149763411001722 Entorhinal Cortex Inputs and Outputs (CA1 -> TFTH, abstract)] || || [BrainAreaNDM NDM] || [BrainRegionNDM_NC_AL_DMPFC NDM.NC.AL.DMPFC] || Dorsomedial Prefrontal Cortex || excitatory-glu || uncertain || [http://journal.frontiersin.org/article/10.3389/fncom.2011.00001/full Gating of medial prefrontal activity by the entorhinal cortex (HC -> MPFC, abstract)] || = Thirdparty Circuits = (generated) * [http://www.nature.com/nrn/journal/v5/n1/images/nrn1299-f4.jpg Medial mammillary nucleus and theta rhythm] - see [http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F4.html Reference] (CT.MMB-THETA) AVTH=[BrainRegionFMM_FD_TH_AV Anteroventral Nucleus,FMM.FD.TH.AV] HF=[BrainCenterFMM_FT_HF Hippocampal Formation,FMM.FT.HF] MMB=[BrainRegionFMM_FD_MB_MMB Medial Mammillary Nucleus,FMM.FD.MB.MMB] RSP=[BrainRegionNCP_NC_MPL_RSC Retrosplenial Cortex,NCP.NC.MPL.RSC] SEP=[BrainCenterFAM_FT_SEP Septal Nuclei,FAM.FT.SEP] SupraMM=[BrainRegionLAC_FD_HT_SUM Supramammillary Nucleus,LAC.FD.HT.SUM] VTN=[BrainRegionLMC_MM_VTA Ventral Tegmental Area,LMC.MM.VTA] unavailable * [http://www.scholarpedia.org/w/images/6/63/Taube_Figure_5a.png Head Direction Cell Circuit] - see [http://www.scholarpedia.org/article/Head_direction_cells Reference] (CT.HEAD-DIRECTION) AD=[BrainRegionFMM_FD_TH_AD Anterodorsal Nucleus,FMM.FD.TH.AD] DTN=[BrainRegionLMC_HT_TG_LDT Laterodorsal Tegmental Nucleus,LMC.HT.TG.DTG] EC=Entorhinal Cortex,FMM.NC.PH.ET (see [BrainCenterNC_PHA_RH Rhinal Cortex]) HC=Hippocampus,FMM.FT.HC (see [BrainCenterFMM_FT_HF Hippocampal Formation]) IPD=[BrainRegionFEC_HT_TG_IPD Interpeduncular Nucleus,FEC.HT.TG.IPD] LD=[BrainRegionFMM_FD_TH_LD Lateral Dorsal Nucleus of Thalamus,FMM.FD.TH.LD] LHAB=[BrainCenterFAM_FD_HB Habenula,FAM.FD.HB] LMB=[BrainRegionFMM_FD_MB_LMB Lateral Mammillary Nucleus,FMM.FD.MB.LMB] MVSN=[BrainRegionLPC_HT_MVBN Medial Vestibular Nucleus,LPC.HT.MVBN] NPRP=[BrainRegionLRC_HL_NPH Prepositus Nucleus,LRC.HL.NPH] PC=Parietal Lobe,NC.LOBE.PAR PRHC=[BrainRegionFMM_NC_PH_POR Postrhinal Cortex,FMM.NC.PH.POR] PSUB=[BrainRegionFMM_NC_PH_POS Postsubiculum,FMM.NC.PH.POS] RSP=[BrainRegionNCP_NC_MPL_RSC Retrosplenial Cortex,NCP.NC.MPL.RSC] SUPGEN=[BrainRegionNSA_FD_TH_SG Suprageniculate Nucleus of Thalamus,NSA.FD.TH.SG] VC=[BrainCenterNC_LOBE_OCC Occipital Lobe,NC.LOBE.OCC] unavailable * [http://media.wiley.com/mrw_images/compphys/articles/cp010508/image_n/ncp01050839.jpg Entorhinal Cortex Inputs and Outputs] - see [http://www.sciencedirect.com/science/article/pii/S0149763411001722 Reference] (CT.ENTORHINAL-CORTEX) CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (see [BrainCenterFMM_FT_HF Hippocampal Formation]) EC=Entorhinal Cortex,FMM.NC.PH.ET (see [BrainCenterNC_PHA_RH Rhinal Cortex]) TFTH=[BrainRegionFMM_NC_PH_POR Postrhinal Cortex,FMM.NC.PH.POR] unavailable * [http://learnmem.cshlp.org/content/14/11/714/F1.large.jpg Attractor Network in Hippocampus] - see [http://learnmem.cshlp.org/content/14/11/714/F1.expansion Reference] (CT.ATTRACTOR-NETWORK) AN=Anterior Nucleus of Thalamus,FD.TH.AN (see [BrainCenterFD_TH_CR Cognitive Thalamus]) CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (see [BrainCenterFMM_FT_HF Hippocampal Formation]) CA3=Dorsomedial Cornu Ammonis of Hippocampus,FMM.FT.HC.CA3 (see [BrainCenterFMM_FT_HF Hippocampal Formation]) DG=[BrainRegionFMM_FT_HC_DG Dentate Gyrus,FMM.FT.HC.DG] EC=Entorhinal Cortex,FMM.NC.PH.ET (see [BrainCenterNC_PHA_RH Rhinal Cortex]) MBIN=[BrainRegionFMM_FD_MB_MMB Medial Mammillary Nucleus,FMM.FD.MB.MMB] MBOUT=[BrainRegionFMM_FD_MB_LMB Lateral Mammillary Nucleus,FMM.FD.MB.LMB] NACC=Accumbens Nucleus,FEC.FT.ACC (see [BrainCenterFEC_FT_BG Basal Ganglia]) PERI=[BrainRegionFMM_NC_PH_PER Perirhinal Cortex,FMM.NC.PH.PER] PRESUB=[BrainRegionFMM_NC_PH_PRS Presubiculum,FMM.NC.PH.PRS] SEP=[BrainCenterFAM_FT_SEP Septal Nuclei,FAM.FT.SEP] SUB=Subiculum,FMM.FT.HF.SUB (see [BrainCenterFMM_FT_HF Hippocampal Formation]) unavailable * [http://www.nature.com/nrn/journal/v3/n2/images/nrn726-f3.jpg McNaughton Spatial Processing Network] - see [http://www.nature.com/nrn/journal/v3/n2/fig_tab/nrn726_F3.html Reference] (CP.VISUAL-SPATIAL-PROCESSING) EnthCortex=Entorhinal Cortex,FMM.NC.PH.ET (see [BrainCenterNC_PHA_RH Rhinal Cortex]) HF=[BrainCenterFMM_FT_HF Hippocampal Formation,FMM.FT.HF] ITCortex=[BrainCenterNSA_NC_IT Inferotemporal Area,NSA.NC.IT] PCGRSP=[BrainCenterNC_MPL Medial Parietal Lobule,NC.MPL] ParInsVestCortex=[BrainRegionNSA_NC_IPS_VIP Ventral Intraparietal Sulcus,NSA.NC.IPS.VIP] PosteriorParietalCortex=[BrainRegionNPE_NC_SPL_PG Caudal Precuneus,NPE.NC.SPL.PG] SUB=Subiculum,FMM.FT.HF.SUB (see [BrainCenterFMM_FT_HF Hippocampal Formation]) SomSensCortex=[BrainRegionNCP_NC_PG_S1 Primary Somatosensory Cortex,NCP.NC.PG.S1] VisualCortex=[BrainCenterNC_LOBE_OCC Occipital Lobe,NC.LOBE.OCC] unavailable * [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/emotional_top.jpg Prefrontal Cortex (PFC) in emotional behavior] - see [https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 Reference] (CF.PFC-EMOTIONS) ACG=Anterior Cingulate Cortex,NC.AL.ACG (see [BrainCenterNC_ACG Anterior Cingulate Area]) AM=[BrainCenterFAM_FT_AM Amygdala,FAM.FT.AM] HCA=Hippocampus,FMM.FT.HC (see [BrainCenterFMM_FT_HF Hippocampal Formation]) HT=[BrainCenterFD_HT Hypothalamus,FD.HT] LPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see [BrainCenterNC_AL_LPFC Lateral Prefrontal Cortex]) OPFC=Orbitofrontal Cortex,NC.AL.OPFC (see [BrainCenterNC_AL_OMPFC Orbitomedial Prefrontal Cortex]) PCA=[BrainCenterNC_MPL Medial Parietal Lobule,NC.MPL] PN=Pontine Nuclear Complex,HT.PN (see [BrainCenterHT_SN Metencephalic Sensory Nuclei]) TH=Mediodorsal Nucleus of Thalamus,FD.TH.MD (see [BrainCenterFD_TH_CR Cognitive Thalamus]) unavailable * [http://www.nature.com/nrn/journal/v5/n7/images/nrn1432-f2.jpg Feeling] - see [http://www.nature.com/nrn/journal/v5/n7 Reference] (CF.FEELING) AN=Anterior Nucleus of Thalamus,FD.TH.AN (see [BrainCenterFD_TH_CR Cognitive Thalamus]) CG=[BrainRegionNCP_NC_MPL_PSCG Posterior Cingulate Cortex,NCP.NC.MPL.PSCG] HC=Hippocampus,FMM.FT.HC (see [BrainCenterFMM_FT_HF Hippocampal Formation]) HT=[BrainCenterFD_HT Hypothalamus,FD.HT] unavailable * [http://www.frontiersin.org/files/Articles/1854/fncom-05-00001-HTML/image_m/fncom-05-00001-g006.jpg Gating of medial prefrontal activity by the entorhinal cortex] - see [http://journal.frontiersin.org/article/10.3389/fncom.2011.00001/full Reference] (CF.EC-MPFC) EC=Entorhinal Cortex,FMM.NC.PH.ET (see [BrainCenterNC_PHA_RH Rhinal Cortex]) HC=Hippocampus,FMM.FT.HC (see [BrainCenterFMM_FT_HF Hippocampal Formation]) MPFC=Medial Prefrontal Cortex,NC.AL.MPFC (see [BrainCenterNC_AL_OMPFC Orbitomedial Prefrontal Cortex]) unavailable * [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/am/hippocampo-amygdala-projections.png Detailed amygdalohippocampal projections] - see [https://books.google.ru/books?id=P3fSBwAAQBAJ Reference] (CF.AM-HC-DET) ABmg=[BrainRegionFAM_FT_AM_AB Accessory Basal Amygdaloid Nucleus,FAM.FT.AM.AB] Bmg=[BrainRegionFAM_FT_AM_BM Magnocellular Basal Amygdaloid Nucleus,FAM.FT.AM.BM] Bpc=[BrainRegionFAM_FT_AM_BP Parvicellular Basal Amygdaloid Nucleus,FAM.FT.AM.BP] CA1D=[BrainRegionFMM_FT_HC_CA1D Distal CA1 of Hippocampus,FMM.FT.HC.CA1D] CA1P=[BrainRegionFMM_FT_HC_CA1P Proximal CA1 of Hippocampus,FMM.FT.HC.CA1P] L=Lateral Amygdaloid Nucleus,FAM.FT.AM.LA (see [BrainCenterFAM_FT_AM Amygdala]) PaS=[BrainRegionFMM_NC_PH_PAS Parasubiculum,FMM.NC.PH.PAS] PrS=[BrainRegionFMM_NC_PH_PRS Presubiculum,FMM.NC.PH.PRS] unavailable = References = (generated) * http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F4.html * http://www.scholarpedia.org/article/Head_direction_cells * http://www.sciencedirect.com/science/article/pii/S0149763411001722 * http://learnmem.cshlp.org/content/14/11/714/F1.expansion * http://www.nature.com/nrn/journal/v3/n2/fig_tab/nrn726_F3.html * https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 * http://www.nature.com/nrn/journal/v5/n7 * http://journal.frontiersin.org/article/10.3389/fncom.2011.00001/full * https://books.google.ru/books?id=P3fSBwAAQBAJ