#summary Medial Mammillary Nucleus @@[Home] -> [BiologicalLifeResearch] -> [BrainAreaFMM] -> [BrainRegionFMM_FD_MB_MMB] ---- This page covers biological details of component Medial Mammillary Nucleus. Region is part of aHuman target integrated biological model. * *Top-down path to region*: Forebrain Diencephalon -> [BrainCenterFD_HT Hypothalamus] (FD.HT) -> Mammillary Body (FD.MB) -> [BrainRegionFMM_FD_MB_MMB Medial Mammillary Nucleus] (FMM.FD.MB.MMB) (see [OverallMindMaps Mind Maps]) * *Type*: nucleus * *Quality*: L0 * *Brain area*: [BrainAreaFMM Forebrain - Memory Management Area] (FMM) * *Area circuit*: Theta Waves Control (MMATHETA) * *Role*: processor.memory.space * *Function*: Relay for impulses coming from AM and HC * *Notes to function*: * Memory, recognition, spatial awareness, and interpreting the context of events (generated) = Components = (generated) *Component items*: * *Mediolateral Mammillary Nucleus* * *Medial Part of Medial Mammillary Nucleus* = Connectivity = (generated) http://ahuman.org/svn/ahwiki/images/dot/FMM.FD.MB.MMB.dot.png *Inbound Region Connections:* || *Source Area* || *Source Region* || *Source Name* || *Type* || *Role* || *Reference* || || [BrainAreaFAM FAM] || [BrainRegionFAM_FT_SEP_DBB FAM.FT.SEP.DBB] || Diagonal Band of Broca || inhibitory-gaba || uncertain ||[http://www.thebrainlabs.com Cingulate Gyrus (SEP -> HT, abstract)] || || || [BrainRegionFAM_FT_SEP_MED FAM.FT.SEP.MED] || Medial Septal Nucleus || inhibitory-gaba || uncertain ||[http://www.thebrainlabs.com Cingulate Gyrus (SEP -> HT, abstract)] || || [BrainAreaFMM FMM] || [BrainRegionFMM_FT_HC_CA1P FMM.FT.HC.CA1P] || Proximal CA1 of Hippocampus || excitatory-glu || uncertain ||[http://www.nature.com/nrn/journal/v5/n7 Feeling (HC -> HT, abstract)] || || || [BrainRegionFMM_FT_HF_SUBD FMM.FT.HF.SUBD] || Distal Subiculum || excitatory-glu || uncertain ||[http://highered.mcgraw-hill.com/sites/dl/free/0071402357/156721/figure350_1.html Principal Connections of Hippocampus (HC -> MB, abstract)] || || || [BrainRegionFMM_FT_HF_SUBP FMM.FT.HF.SUBP] || Proximal Subiculum || excitatory-glu || uncertain ||[http://highered.mcgraw-hill.com/sites/dl/free/0071402357/156721/figure350_1.html Principal Connections of Hippocampus (HC -> MB, abstract)] || || || [BrainRegionFMM_NC_PH_MEC FMM.NC.PH.MEC] || Medial Entorhinal Cortex || excitatory-glu || uncertain ||[http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F2.html Mammillary bodies: two memory systems in one (MedialEC -> MMB, abstract)] || || || [BrainRegionFMM_NC_PH_PRS FMM.NC.PH.PRS] || Presubiculum || excitatory-glu || uncertain ||[http://learnmem.cshlp.org/content/14/11/714/F1.expansion Attractor Network in Hippocampus (PRESUB -> MBIN)] || || [BrainAreaLAC LAC] || [BrainRegionLAC_FD_HT_TBM LAC.FD.HT.TBM] || Tuberomammillary Nucleus || excitatory-glu || uncertain ||[http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F2.html Mammillary bodies: two memory systems in one (TuberoMM -> MMB, abstract)] || || [BrainAreaLMC LMC] || [BrainRegionLMC_MM_RP_SUC LMC.MM.RP.SUC] || Superior Central Raphe Nucleus || modulatory-5ht || uncertain ||(unknown reference) || || || [BrainRegionLMC_MM_VTA LMC.MM.VTA] || Ventral Tegmental Area || modulatory-da || uncertain ||[http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F2.html Mammillary bodies: two memory systems in one (VTN -> MMB)] || *Outbound Region Connections:* || *Target Area* || *Target Region* || *Target Name* || *Type* || *Role* || *Reference* || || [BrainAreaFMM FMM] || [BrainRegionFMM_FD_TH_AV FMM.FD.TH.AV] || Anteroventral Nucleus || excitatory-glu || uncertain || [http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F2.html Mammillary bodies: two memory systems in one (MMB -> AVTH)] || || [BrainAreaLLC LLC] || [BrainRegionLLC_HT_PN_RSP LLC.HT.PN.RSP] || Rostral Pontine Nucleus || excitatory-glu || uncertain || [https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 Prefrontal Cortex (PFC) in emotional behavior (HT -> PN, abstract)] || || || [BrainRegionLLC_HT_PRF_RTMG LLC.HT.PRF.RTMG] || Pontine Reticulotegmental Nucleus || excitatory-glu || uncertain || [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/mb.jpg Mammillary Body (MMB -> RTG)] || || [BrainAreaNCP NCP] || [BrainRegionNCP_FD_TH_AM NCP.FD.TH.AM] || Anteromedial Nucleus || excitatory-glu || uncertain || [http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F2.html Mammillary bodies: two memory systems in one (MMB -> AMTH)] || = Thirdparty Circuits = (generated) * [http://www.nature.com/nrn/journal/v5/n1/images/nrn1299-f4.jpg Medial mammillary nucleus and theta rhythm] - see [http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F4.html Reference] (CT.MMB-THETA) AVTH=[BrainRegionFMM_FD_TH_AV Anteroventral Nucleus,FMM.FD.TH.AV] HF=[BrainCenterFMM_FT_HF Hippocampal Formation,FMM.FT.HF] MMB=[BrainRegionFMM_FD_MB_MMB Medial Mammillary Nucleus,FMM.FD.MB.MMB] RSP=[BrainRegionNCP_NC_MPL_RSC Retrosplenial Cortex,NCP.NC.MPL.RSC] SEP=[BrainCenterFAM_FT_SEP Septal Nuclei,FAM.FT.SEP] SupraMM=[BrainRegionLAC_FD_HT_SUM Supramammillary Nucleus,LAC.FD.HT.SUM] VTN=[BrainRegionLMC_MM_VTA Ventral Tegmental Area,LMC.MM.VTA] unavailable * [http://www.nature.com/nrn/journal/v5/n1/images/nrn1299-f2.jpg Mammillary bodies: two memory systems in one] - see [http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F2.html Reference] (CT.MB-MEMORY) ADTH=[BrainRegionFMM_FD_TH_AD Anterodorsal Nucleus,FMM.FD.TH.AD] AMTH=[BrainRegionNCP_FD_TH_AM Anteromedial Nucleus,NCP.FD.TH.AM] AVTH=[BrainRegionFMM_FD_TH_AV Anteroventral Nucleus,FMM.FD.TH.AV] DTN=[BrainRegionLMC_HT_TG_LDT Laterodorsal Tegmental Nucleus,LMC.HT.TG.LDT] LMB=[BrainRegionFMM_FD_MB_LMB Lateral Mammillary Nucleus,FMM.FD.MB.LMB] MMB=[BrainRegionFMM_FD_MB_MMB Medial Mammillary Nucleus,FMM.FD.MB.MMB] MedialEC=Entorhinal Cortex,FMM.NC.PH.ET (see [BrainCenterNC_PHA_RH Rhinal Cortex]) PAS=[BrainRegionFMM_NC_PH_PAS Parasubiculum,FMM.NC.PH.PAS] POS=[BrainRegionFMM_NC_PH_POS Postsubiculum,FMM.NC.PH.POS] PRS=[BrainRegionFMM_NC_PH_PRS Presubiculum,FMM.NC.PH.PRS] SEP=[BrainCenterFAM_FT_SEP Septal Nuclei,FAM.FT.SEP] SUB=Subiculum,FMM.FT.HF.SUB (see [BrainCenterFMM_FT_HF Hippocampal Formation]) SupraMM=[BrainRegionLAC_FD_HT_SUM Supramammillary Nucleus,LAC.FD.HT.SUM] TuberoMM=Lateral Tuberal Nuclei,LAC.FD.HT.LTUB (see [BrainCenterFD_HT Hypothalamus]) VTN=[BrainRegionLMC_MM_VTA Ventral Tegmental Area,LMC.MM.VTA] unavailable * [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/mb.jpg Mammillary Body] (unknown reference) (CT.LMB-MMB) LMB=[BrainRegionFMM_FD_MB_LMB Lateral Mammillary Nucleus,FMM.FD.MB.LMB] MMB=[BrainRegionFMM_FD_MB_MMB Medial Mammillary Nucleus,FMM.FD.MB.MMB] RTG=[BrainRegionLLC_HT_PRF_RTMG Pontine Reticulotegmental Nucleus,LLC.HT.PRF.RTMG] unavailable * [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/emotional_top.jpg Prefrontal Cortex (PFC) in emotional behavior] - see [https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 Reference] (CF.PFC-EMOTIONS) ACG=Anterior Cingulate Cortex,NC.AL.ACG (see [BrainCenterNC_ACG Anterior Cingulate Area]) AM=[BrainCenterFAM_FT_AM Amygdala,FAM.FT.AM] HCA=Hippocampus,FMM.FT.HC (see [BrainCenterFMM_FT_HF Hippocampal Formation]) HT=[BrainCenterFD_HT Hypothalamus,FD.HT] LPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see [BrainCenterNC_AL_LPFC Lateral Prefrontal Cortex]) OPFC=Orbitofrontal Cortex,NC.AL.OPFC (see [BrainCenterNC_AL_OMPFC Orbitomedial Prefrontal Cortex]) PCA=[BrainCenterNC_MPL Medial Parietal Lobule,NC.MPL] PN=Pontine Nuclear Complex,HT.PN (see [BrainCenterHT_SN Metencephalic Sensory Nuclei]) TH=Mediodorsal Nucleus of Thalamus,FD.TH.MD (see [BrainCenterFD_TH_CR Cognitive Thalamus]) unavailable * [http://learnmem.cshlp.org/content/18/6/384/F1.large.jpg Contributions of Diencephalon to Recognition Memory] - see [http://learnmem.cshlp.org/content/18/6/384/F1.expansion.html Reference] (CT.RECOGNITION-MEMORY) AD=[BrainRegionFMM_FD_TH_AD Anterodorsal Nucleus,FMM.FD.TH.AD] AM=[BrainRegionNCP_FD_TH_AM Anteromedial Nucleus,NCP.FD.TH.AM] AN=Anterior Nucleus of Thalamus,FD.TH.AN (see [BrainCenterFD_TH_CR Cognitive Thalamus]) AV=[BrainRegionFMM_FD_TH_AV Anteroventral Nucleus,FMM.FD.TH.AV] CM=[BrainRegionFEC_FD_TH_CM Centromedian Nucleus of Thalamus,FEC.FD.TH.CM] DLPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see [BrainCenterNC_AL_LPFC Lateral Prefrontal Cortex]) EC=Entorhinal Cortex,FMM.NC.PH.ET (see [BrainCenterNC_PHA_RH Rhinal Cortex]) HC=Hippocampus,FMM.FT.HC (see [BrainCenterFMM_FT_HF Hippocampal Formation]) LD=[BrainRegionFMM_FD_TH_LD Lateral Dorsal Nucleus of Thalamus,FMM.FD.TH.LD] MB=[BrainRegionFMM_FD_MB_MMB Medial Mammillary Nucleus,FMM.FD.MB.MMB] MDmc=Mediodorsal Nucleus of Thalamus,FD.TH.MD (see [BrainCenterFD_TH_CR Cognitive Thalamus]) MID=Midline Nuclear Group of Thalamus,FD.TH.MTH (see [BrainCenterFD_TH_CR Cognitive Thalamus]) MPFC=Orbitofrontal Cortex,NC.AL.OPFC (see [BrainCenterNC_AL_OMPFC Orbitomedial Prefrontal Cortex]) OFC=Orbitofrontal Cortex,NC.AL.OPFC (see [BrainCenterNC_AL_OMPFC Orbitomedial Prefrontal Cortex]) Parasub=[BrainRegionFMM_NC_PH_PAS Parasubiculum,FMM.NC.PH.PAS] Perirhinal=[BrainRegionFMM_NC_PH_PER Perirhinal Cortex,FMM.NC.PH.PER] PostCingulate=[BrainRegionNCP_NC_MPL_PSCG Posterior Cingulate Cortex,NCP.NC.MPL.PSCG] Presub=[BrainRegionFMM_NC_PH_PRS Presubiculum,FMM.NC.PH.PRS] Sub=Subiculum,FMM.FT.HF.SUB (see [BrainCenterFMM_FT_HF Hippocampal Formation]) SubPrePara=Subiculum,FMM.FT.HF.SUB (see [BrainCenterFMM_FT_HF Hippocampal Formation]) mPULV=[BrainRegionNPE_FD_TH_MPV Medial Pulvinar,NPE.FD.TH.MPV] unavailable * [http://neurondevelopment.org/userfiles/image/hippocampal-dev-page.gif Hippocampus and Septal Area] - see [http://neurondevelopment.org/hippocampal-development Reference] (CT.HC-AND-SEPTAL) CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (see [BrainCenterFMM_FT_HF Hippocampal Formation]) LateralSeptal=[BrainCenterFAM_FT_SEP Septal Nuclei,FAM.FT.SEP] MB=[BrainRegionFMM_FD_MB_MMB Medial Mammillary Nucleus,FMM.FD.MB.MMB] unavailable * [http://highered.mcgraw-hill.com/sites/dl/free/0071402357/156721/figure350_1.gif Principal Connections of Hippocampus] - see [http://highered.mcgraw-hill.com/sites/dl/free/0071402357/156721/figure350_1.html Reference] (CT.CINGULUM-CONNECTIONS) AM=[BrainCenterFAM_FT_AM Amygdala,FAM.FT.AM] AN=Anterior Nucleus of Thalamus,FD.TH.AN (see [BrainCenterFD_TH_CR Cognitive Thalamus]) DG=[BrainRegionFMM_FT_HC_DG Dentate Gyrus,FMM.FT.HC.DG] DorsalCingulate=[BrainRegionNDM_NC_AL_DACG Dorsal Anterior Cingulate Area,NDM.NC.AL.DACG] EC=Entorhinal Cortex,FMM.NC.PH.ET (see [BrainCenterNC_PHA_RH Rhinal Cortex]) HC=Subiculum,FMM.FT.HF.SUB (see [BrainCenterFMM_FT_HF Hippocampal Formation]) MB=[BrainRegionFMM_FD_MB_MMB Medial Mammillary Nucleus,FMM.FD.MB.MMB] PosteriorCingulate=[BrainRegionNCP_NC_MPL_PSCG Posterior Cingulate Cortex,NCP.NC.MPL.PSCG] SEP=[BrainCenterFAM_FT_SEP Septal Nuclei,FAM.FT.SEP] SUB=Subiculum,FMM.FT.HF.SUB (see [BrainCenterFMM_FT_HF Hippocampal Formation]) VentralCingulate=[BrainRegionNDM_NC_AL_VACG Ventral Anterior Cingulate Area,NDM.NC.AL.VACG] unavailable * [http://learnmem.cshlp.org/content/14/11/714/F1.large.jpg Attractor Network in Hippocampus] - see [http://learnmem.cshlp.org/content/14/11/714/F1.expansion Reference] (CT.ATTRACTOR-NETWORK) AN=Anterior Nucleus of Thalamus,FD.TH.AN (see [BrainCenterFD_TH_CR Cognitive Thalamus]) CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (see [BrainCenterFMM_FT_HF Hippocampal Formation]) CA3=Dorsomedial Cornu Ammonis of Hippocampus,FMM.FT.HC.CA3 (see [BrainCenterFMM_FT_HF Hippocampal Formation]) DG=[BrainRegionFMM_FT_HC_DG Dentate Gyrus,FMM.FT.HC.DG] EC=Entorhinal Cortex,FMM.NC.PH.ET (see [BrainCenterNC_PHA_RH Rhinal Cortex]) MBIN=[BrainRegionFMM_FD_MB_MMB Medial Mammillary Nucleus,FMM.FD.MB.MMB] MBOUT=[BrainRegionFMM_FD_MB_LMB Lateral Mammillary Nucleus,FMM.FD.MB.LMB] NACC=Accumbens Nucleus,FEC.FT.ACC (see [BrainCenterFEC_FT_BG Basal Ganglia]) PERI=[BrainRegionFMM_NC_PH_PER Perirhinal Cortex,FMM.NC.PH.PER] PRESUB=[BrainRegionFMM_NC_PH_PRS Presubiculum,FMM.NC.PH.PRS] SEP=[BrainCenterFAM_FT_SEP Septal Nuclei,FAM.FT.SEP] SUB=Subiculum,FMM.FT.HF.SUB (see [BrainCenterFMM_FT_HF Hippocampal Formation]) unavailable = References = (generated) * http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F4.html * http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F2.html * https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 * http://learnmem.cshlp.org/content/18/6/384/F1.expansion.html * http://neurondevelopment.org/hippocampal-development * http://highered.mcgraw-hill.com/sites/dl/free/0071402357/156721/figure350_1.html * http://learnmem.cshlp.org/content/14/11/714/F1.expansion